Akers JC, Tan M. Molecular mechanism of tryptophan-dependent transcriptional regulation in Chlamydia trachomatis. J. Bacteriol. 188: 4236-4243 (2006).

Akowski JP, Bauerle R. Steady-state kinetics and inhibitor binding of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (tryptophan sensitive) from Escherichia coli. Biochemistry 36: 15817-15822 (1997).

Ambikapathy J, Marshall JS, Hocart CH, Hardham AR. The role of proline in osmoregulation in Phytophthora nicotianae. Fungal Genet. Biol. 35: 287-299 (2002).

Anjaiah V, Koedam N, Nowak-Thompson B, Loper JE, Hofte M, Tambong JT, Cornelis P. Involvement of phenazines and anthranilate in the antagonism of Pseudomonas aeruginosa PNA1 and Tn5 derivatives toward Fusarium spp. and Pythium spp. Mol. Plant Microbe Interact. 11: 847-854 (1998).

Bahar I, Jernigan RL. Cooperative fluctuations and subunit communication in tryptophan synthase. Biochemistry 38: 3478-3490 (1999).

Bak S, Feyereisen R. The involvement of two P450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis. Plant Physiol. 127: 108-118 (2001).

Baker DH. Comparative nutrition and metabolism: explication of open questions with emphasis on protein and amino acids. Proc. Natl. Acad. Sci. U.S.A. 102: 17897-1902 (2005).

Balderas-Hernandez VE, Sabido-Ramos A, Silva P, Cabrera-Valladares N, Hernandez-Chavez G, Baez-Viveros JL, Martinez A, Bolívar F, Gosset G. Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli. Microb. Cell Fact. 8: 19 (2009).

Barczak AJ, Zhao J, Pruitt KD, Last RL. 5-Fluoroindole resistance identifies tryptophan synthase beta subunit mutants in Arabidopsis thaliana. Genetics 140: 303-313 (1995).

Barends TR, Dunn MF, Schlichting I. Tryptophan synthase, an allosteric molecular factory. Curr. Opin. Chem. Biol. 12: 593-600 (2008).

Bartel B. Auxin biosynthesis. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48: 51-66 (1997).

Bartling D, Seedorf M, Schmidt RC, Weiler EW. Molecular characterization of two cloned nitrilases from Arabidopsis thaliana: key enzymes in biosynthesis of the plant hormone indole-3-acetic acid. Proc. Natl. Acad. Sci. U.S.A. 91: 6021-6025 (1994).

Bernasconi P, Walters EW, Woodworth AR, Siehl DL, Stone TE, Subramanian MV. Functional expression of Arabidopsis thaliana anthranilate synthase subunit I in Escherichia coli. Plant Physiol. 106: 353-358 (1994).

Bohlmann J, Lins T, Martin W, Eilert U. Anthranilate synthase from Ruta graveolens. Duplicated AS alpha genes encode tryptophan-sensitive and tryptophan-insensitive isoenzymes specific to amino acid and alkaloid biosynthesis. Plant Physiol. 111: 507-514 (1996).

Brader G, Tas E, Palva ET. Jasmonate-dependent induction of indole glucosinolates in Arabidopsis by culture filtrates of the nonspecific pathogen Erwinia carotovora. Plant Physiol. 126: 849-860 (2001).

Brandl MT, Lindow SE. Cloning and characterization of a locus encoding an indolepyruvate decarboxylase involved in indole-3-acetic acid synthesis in Erwinia herbicola. Appl. Environ. Microbiol. 62: 4121-4128 (1996).

Braus GH. Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway. Microbiol. Rev. 55: 349-370 (1991).

Brzovic PS, Kayastha AM, Miles EW, Dunn MF. Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium. Biochemistry 31: 1180-1190 (1992).

Buvinger WE, Stone LC, Heath HE. Biochemical genetics of tryptophan synthesis in Pseudomonas acidovorans. J. Bacteriol. 147: 62-68 (1981).

Byrne KM, Smith SK, Ondeyka JG. Biosynthesis of nodulisporic acid A: Precursor studies. J. Am. Chem. Soc. 124: 7055-7060 (2002).

Campos-Tamayo F, Hernandez-Domínguez E, Vazquez-Flota F. Vindoline formation in shoot cultures of Catharanthus roseus is synchronously activated with morphogenesis through the last biosynthetic step. Ann. Bot. (Lond.) 102: 409-415 (2008).

Canel C, Lopes-Cardoso MI, Whitmer S, van der Fits L, Pasquali G, van der Heijden R, Hoge JH, Verpoorte R. Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus. Planta 205: 414-419 (1998).

Cash MT, Miles EW, Phillips RS. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole. Arch. Biochem. Biophys. 432: 233-243 (2004).

Casino P, Niks D, Ngo H, Pan P, Brzovic P, Blumenstein L, Barends TR, Schlichting I, Dunn MF. Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding. Biochemistry 46: 7728-7739 (2007).

Celenza JL. Metabolism of tyrosine and tryptophan - new genes for old pathways. Curr. Opin. Plant Biol. 4: 234-240 (2001).

Celenza JL, Quiel JA, Smolen GA, Merrikh H, Silvestro AR, Normanly J, Bender J. The Arabidopsis ATR1 Myb transcription factor controls indolic glucosinolate homeostasis. Plant Physiol. 137: 253-262 (2005).

Chen G, Yanofsky C. Tandem transcription and translation regulatory sensing of uncharged tryptophan tRNA. Science 301: 211-213 (2003).

Chen H, Xiong L. The short-rooted vitamin B6-deficient mutant pdx1 has impaired local auxin biosynthesis. Planta 229: 1303-1310 (2009).

Cho HJ, Brotherton JE, Song HS, Widholm JM. Increasing tryptophan synthesis in a forage legume Astragalus sinicus by expressing the tobacco feedback-insensitive anthranilate synthase (ASA2) gene. Plant Physiol. 123: 1069-1076 (2000).

Chong CK, Shin HJ, Chang SI, Choi JD. Role of tryptophanyl residues in tobacco acetolactate synthase. Biochem. Biophys. Res. Commun. 259: 136-140 (1999).

Chung IM, Hong SB, Peebles CA, Kim JA, San KY. Effect of the engineered indole pathway on accumulation of phenolic compounds in Catharanthus roseus hairy roots. Biotechnol. Prog. 23: 327-332 (2007).

Cohen JD, Slovin JP, Hendrickson AM. Two genetically discrete pathways convert tryptophan to auxin: more redundancy in auxin biosynthesis. Trends Plant Sci. 8: 197-199 (2003).

Cohn W, Crawford IP. Regulation of enzyme synthesis in the tryptophan pathway of Acinetobacter calcoaceticus. J. Bacteriol. 127: 367-379 (1976).

Connelly JA, Conn EE. Tyrosine biosynthesis in Sorghum bicolor: isolation and regulatory properties of arogenate dehydrogenase. Z. Naturforsch. [C] 41: 69-78 (1986).

Cooke TJ, Poli D, Sztein AE, Cohen JD. Evolutionary patterns in auxin action. Plant Mol. Biol. 49: 319-338 (2002).

Darimont B, Stehlin C, Szadkowski H, Kirschner K. Mutational analysis of the active site of indoleglycerol phosphate synthase from Escherichia coli. Protein Sci. 7: 1221-1232 (1998).

De Luca V. Chapter 9. Metabolic Engineering of Crops with the Tryptophan Decarboxylase of Catharanthus roseus. In "Metabolic Engineering of Plant Secondary Metabolism" (Verpoorte R, Alfermann AW, eds), Kluwer Academic Publishers, Dortrecht, The Netherlands, pp. 179-194 (2000).

De Luca V, Laflamme P. The expanding universe of alkaloid biosynthesis. Curr. Opin. Plant Biol. 4: 225-233 (2001).

Diksic M. Labelled alpha-methyl-L-tryptophan as a tracer for the study of the brain serotonergic system. J. Psychiatry Neurosci. 26: 293-303 (2001).

Diksic M, Young SN. Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan. J. Neurochem. 78: 1185-1200 (2001).

Ditengou FA, Lapeyrie F. Hypaphorine from the ectomycorrhizal fungus Pisolithus tinctorius counteracts activities of indole-3-acetic acid and ethylene but not synthetic auxins in eucalypt seedlings. Mol. Plant Microbe Interact. 13: 151-158 (2000).

Dosselaere F, Lambrecht M, Vanderleyden J. Isolation and sequence analysis of the trpBA gene cluster, encoding tryptophan synthase, from Azospirillum brasilense. DNA Seq. 11: 287-293 (2000).

Dunn MF, Aguilar V, Brzovic P, Drewe WF Jr, Houben KF, Leja CA, Roy M. The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel. Biochemistry 29: 8598-8607 (1990).

Dunn MF, Niks D, Ngo H, Barends TR, Schlichting I. Tryptophan synthase: the workings of a channeling nanomachine. Trends Biochem. Sci. 33: 254-264 (2008).

Dutcher SK, Galloway RE, Barclay WR, Poortinga G. Tryptophan analog resistance mutations in Chlamydomonas reinhardtii. Genetics 131: 593-607 (1992).

Eaves DJ, Palmer T, Boxer DH. The product of the molybdenum cofactor gene mobB of Escherichia coli is a GTP-binding protein. Eur. J. Biochem. 246: 690-697 (1997).

Eberhard J, Ehrler TT, Epple P, Felix G, Raesecke HR, Amrhein N, Schmid J. Cytosolic and plastidic chorismate mutase isozymes from Arabidopsis thaliana: molecular characterization and enzymatic properties. Plant J. 10: 815-821 (1996).

Ehlert B, Schottler MA, Tischendorf G, Ludwig-Muller J, Bock R. The paramutated SULFUREA locus of tomato is involved in auxin biosynthesis. J. Exp. Bot. 59: 3635-3647 (2008).

Essar DW, Eberly L, Hadero A, Crawford IP. Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications. J. Bacteriol. 172: 884-900 (1990).

Essar DW, Eberly L, Han CY, Crawford IP. DNA sequences and characterization of four early genes of the tryptophan pathway in Pseudomonas aeruginosa. J. Bacteriol. 172: 853-866 (1990).

Facchini PJ, DiCosmo F. Secondary metabolite biosynthesis in cultured cells of Catharanthus roseus (L.) G. Don immobilized by adhesion to glass fibres. Appl. Microbiol. Biotechnol. 35: 382-392 (1991).

Facchini PJ, Huber-Allanach KL, Tari LW. Plant aromatic L-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications. Phytochemistry 54: 121-138 (2000).

Fantes PA, Roberts LM, Huetter R. Free tryptophan pool and tryptophan biosynthetic enzymes in Saccharomyces cerevisiae. Arch. Microbiol. 107: 207-214 (1976).

Farrow JM 3rd, Pesci EC. Two distinct pathways supply anthranilate as a precursor of the Pseudomonas quinolone signal. J. Bacteriol. 189: 3425-3433 (2007).

Fiske MJ, Kane JF. Regulation of phenylalanine biosynthesis in Rhodotorula glutinis. J. Bacteriol. 160: 676-681 (1984).

Forlani G, Lejczak B, Kafarski P. The herbicidally active compound N-2-(5-chloro-pyridyl) aminomethylene bisphosphonic acid acts by inhibiting both glutamine and aromatic amino acid biosynthesis. Aust. J. Plant Physiol. 27: 677-683 (2000).

Forlani G, Lejczak B, Kafarski P. The herbicidally active compound N-2-(6-methyl-pyridyl)- aminomethylene bisphosphonic acid inhibits in vivo aromatic biosynthesis. J. Plant Growth Regul. 18: 73-79 (1999).

Frank W, Baar KM, Qudeimat E, Woriedh M, Alawady A, Ratnadewi D, Gremillon L, Grimm B, Reski R. A mitochondrial protein homologous to the mammalian peripheral-type benzodiazepine receptor is essential for stress adaptation in plants. Plant J. 51: 1004-1018 (2007).

Galili S, Guenoune D, Wininger S, Hana B, Schupper A, Ben-Dor B, Kapulnik Y. Enhanced levels of free and protein-bound threonine in transgenic alfalfa (Medicago sativa L.) expressing a bacterial feedback-insensitive aspartate kinase gene. Transgenic Res. 9: 137-144 (2000).

Gast DA, Jenal U, Wasserfallen A, Leisinger T. Regulation of tryptophan biosynthesis in Methanobacterium thermoautotrophicum Marburg. J. Bacteriol. 176: 4590-4596 (1994).

Gast DA, Wasserfallen A, Pfister P, Ragettli S, Leisinger T. Characterization of Methanobacterium thermoautotrophicum Marburg mutants defective in regulation of L-tryptophan biosynthesis. J. Bacteriol. 179: 3664-3669 (1997).

Ge SM, Xie BE, Chen SF. Characterization of two trpE genes encoding anthranilate synthase alpha-subunit in Azospirillum brasilense. Biochem. Biophys. Res. Commun. 341: 494-499 (2006).

Glawischnig E, Tomas A, Eisenreich W, Spiteller P, Bacher A, Gierl A. Auxin biosynthesis in maize kernels. Plant Physiol. 123: 1109-1120 (2000).

Goddijn OJ, de Kam RJ, Zanetti A, Schilperoort RA, Hoge JH. Auxin rapidly down-regulates transcription of the tryptophan decarboxylase gene from Catharanthus roseus. Plant Mol. Biol. 18: 1113-1120 (1992).

Goddijn OJ, Lohman FP, de Kam RJ, Schilperoort RA, Hoge JH. Nucleotide sequence of the tryptophan decarboxylase gene of Catharanthus roseus and expression of tdc-gusA gene fusions in Nicotiana tabacum. Mol. Gen. Genet. 242: 217-225 (1994).

Goddijn OJ, Pennings EJ, van der Helm P, Schilperoort RA, Verpoorte R, Hoge JH. Overexpression of a tryptophan decarboxylase cDNA in Catharanthus roseus crown gall calluses results in increased tryptamine levels but not in increased terpenoid indole alkaloid production. Transgenic Res. 4: 315-323 (1995).

Gorlach J, Raesecke HR, Rentsch D, Regenass M, Roy P, Zala M, Keel C, Boller T, Amrhein N, Schmid J. Temporally distinct accumulation of transcripts encoding enzymes of the prechorismate pathway in elicitor-treated, cultured tomato cells. Proc. Natl. Acad. Sci. U.S.A. 92: 3166-3170 (1995).

Graf R, Mehmann B, Braus GH. Analysis of feedback-resistant anthranilate synthases from Saccharomyces cerevisiae. J. Bacteriol. 175: 1061-1068 (1993).

Grenville-Briggs LJ, Avrova AO, Bruce CR, Williams A, Whisson SC, Birch PR, van West P. Elevated amino acid biosynthesis in Phytophthora infestans during appressorium formation and potato infection. Fungal Genet. Biol. 42: 244-256 (2005).

Guillet G, De Luca V. Wound-inducible biosynthesis of phytoalexin hydroxycinnamic acid amides of tyramine in tryptophan and tyrosine decarboxylase transgenic tobacco lines. Plant Physiol. 137: 692-699 (2005).

Guillet G, Poupart J, Basurco J, De Luca V. Expression of tryptophan decarboxylase and tyrosine decarboxylase genes in tobacco results in altered biochemical and physiological phenotypes. Plant Physiol. 122: 933-944 (2000).

Harrison AJ, Yu M, Gardenborg T, Middleditch M, Ramsay RJ, Baker EN, Lott JS. The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase. J. Bacteriol. 188: 6081-6091 (2006).

Hettwer S, Sterner R. A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima - Quaternary structure, steady-state kinetics, and putative physiological role. J. Biol. Chem. 277: 8194-8201 (2002).

Hong SB, Peebles CA, Shanks JV, San KY, Gibson SI. Expression of the Arabidopsis feedback-insensitive anthranilate synthase holoenzyme and tryptophan decarboxylase genes in Catharanthus roseus hairy roots. J. Biotechnol. 122: 28-38 (2006).

Hughes EH, Hong SB, Gibson SI, Shanks JV, San KY. Metabolic engineering of the indole pathway in Catharanthus roseus hairy roots and increased accumulation of tryptamine and serpentine. Metab. Eng. 6: 268-276 (2004).

Hutter R, Niederberger P, DeMoss JA. Tryptophan biosynthetic genes in eukaryotic microorganisms. Annu. Rev. Microbiol. 40: 55-77 (1986).

Hyde CC, Miles EW. The tryptophan synthase multienzyme complex: exploring structure-function relationships with X-ray crystallography and mutagenesis. Biotechnology (N.Y.) 8: 27-32 (1990).

Inaba Y, Brotherton JE, Ulanov A, Widholm JM. Expression of a feedback insensitive anthranilate synthase gene from tobacco increases free tryptophan in soybean plants. Plant Cell Rep. 26: 1763-1771 (2007).

Ishihara A, Asada Y, Takahashi Y, Yabe N, Komeda Y, Nishioka T, Miyagawa H, Wakasa K. Metabolic changes in Arabidopsis thaliana expressing the feedback-resistant anthranilate synthase alpha subunit gene OASA1D. Phytochemistry 67: 2349-2362 (2006).

Jacobs DI, Gaspari M, van der Greef J, van der Heijden R, Verpoorte R. Proteome analysis of the medicinal plant Catharanthus roseus. Planta 221: 690-704 (2005).

Jelesko JG, Lara JC, Leigh JA. Rhizobium meliloti mutants with decreased DAHP synthase activity are sensitive to exogenous tryptophan and phenylalanine and form ineffective nodules. Mol. Plant Microbe Interact. 6: 135-143 (1993).

Jensen PJ, Bandurski RS. Metabolism and synthesis of indole-3-acetic acid (IAA) in Zea mays. Levels of IAA during kernel development and the use of in vitro endosperm systems for studying IAA biosynthesis. Plant Physiol. 106: 343-351 (1994).

Jeong MS, Jang SB. Crystallization and X-ray crystallographic studies of wild-type and mutant tryptophan synthase alpha-subunits from Escherichia coli. Mol. Cells 19: 219-222 (2005).

Jeong MS, Jeong JK, Lim WK, Jang SB. Structures of wild-type and P28L/Y173F tryptophan synthase alpha-subunits from Escherichia coli. Biochem. Biophys. Res. Commun. 323: 1257-1264 (2004).

Jeong MS, Jeong JK, Park KS, Kim HT, Lee KM, Lim WK, Jang SB. Crystallization and preliminary X-ray analysis of tryptophan synthase alpha-subunits from Escherichia coli. Acta Crystallogr. D. Biol. Crystallogr. 60: 132-134 (2004).

Jing Y, Cui D, Bao F, Hu Z, Qin Z, Hu Y. Tryptophan deficiency affects the organ growth by retarding cell expansion in Arabidopsis. Plant J. 57: 511-521 (2009).

Jiroutova K, Horak A, Bowler C, Oborník M. Tryptophan biosynthesis in stramenopiles: eukaryotic winners in the diatom complex chloroplast. J. Mol. Evol. 65: 496-511 (2007).

Kawaguchi M, Syono K. The excessive production of indole-3-acetic acid and its significance in studies of the biosynthesis of this regulator of plant growth and development. Plant Cell Physiol. 37: 1043-1048 (1996).

Kawasaki H, Bauerle R, Zon G, Ahmed SA, Miles EW. Site-specific mutagenesis of the alpha subunit of tryptophan synthase from Salmonella typhimurium. Changing arginine 179 to leucine alters the reciprocal transmission of substrate-induced conformational changes between the alpha and beta 2 subunits. J. Biol. Chem. 262: 10678-10683 (1987).

Kim C, Xuong NH, Edwards S, Madhusudan, Yee MC, Spraggon G, Mills SE. The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum. FEBS Lett. 523: 239-246 (2002).

Kim DS, Lee IS, Jang CS, Kang SY, Seo YW. Characterization of the altered anthranilate synthase in 5-methyltryptophan-resistant rice mutants. Plant Cell Rep. 24: 357-365 (2005).

Kim SH, Kronstad JW, Ellis BE. Induction of phenylalanine ammonia-lyase activity by tryptophan in Ustilago maydis. Phytochemistry 58: 849-857 (2001).

Koga J, Syono K, Ichikawa T, Adachi T. Involvement of L-tryptophan aminotransferase in indole-3-acetic acid biosynthesis in Enterobacter cloacae. Biochim. Biophys. Acta 1209: 241-247 (1994).

Koll P, Bode R, Birnbaum D. Regulation of metabolic branch points of aromatic amino acid biosynthesis in Pichia guilliermondii. J. Basic Microbiol. 28: 619-627 (1988).

Krappmann S, Lipscomb WN, Braus GH. Coevolution of transcriptional and allosteric regulation at the chorismate metabolic branch point of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 97: 13585-13590 (2000).

Kriechbaumer V, Weigang L, Fiesselmann A, Letzel T, Frey M, Gierl A, Glawischnig E. Characterisation of the tryptophan synthase alpha subunit in maize. BMC Plant Biol. 8: 44 (2008).

Kuhn DM, Arthur R Jr. Dopamine inactivates tryptophan hydroxylase and forms a redox-cycling quinoprotein: possible endogenous toxin to serotonin neurons. J. Neurosci. 18: 7111-7117 (1998).

Kusnierczyk A, Winge P, Midelfart H, Armbruster WS, Rossiter JT, Bones AM. Transcriptional responses of Arabidopsis thaliana ecotypes with different glucosinolate profiles after attack by polyphagous Myzus persicae and oligophagous Brevicoryne brassicae. J. Exp. Bot. 58: 2537-2552 (2007).

Last RL, Bissinger PH, Mahoney DJ, Radwanski ER, Fink GR. Tryptophan mutants in Arabidopsis: the consequences of duplicated tryptophan synthase beta genes. Plant Cell 3: 345-358 (1991).

Laurichesse H, Tauveron I, Gourdon F, Cormerais L, Champredon C, Charrier S, Rochon C, Lamain S, Bayle G, Laveran H, Thieblot P, Beytout J, Grizard J. Threonine and methionine are limiting amino acids for protein synthesis in patients with AIDS. J. Nutr. 128: 1342-1348 (1998).

Li J, Last RL. The Arabidopsis thaliana trp5 mutant has a feedback-resistant anthranilate synthase and elevated soluble tryptophan. Plant Physiol. 110: 51-59 (1996).

Li SM. Evolution of aromatic prenyltransferases in the biosynthesis of indole derivatives. Phytochemistry Apr 25 [Epub ahead of print] (2009).

Lin C, Paradkar AS, Vining LC. Regulation of an anthranilate synthase gene in Streptomyces venezuelae by a trp attenuator. Microbiology 144: 1971-1980 (1998).

Liu YJ, Li PP, Zhao KX, Wang BJ, Jiang CY, Drake HL, Liu SJ. Corynebacterium glutamicum contains 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that display novel biochemical features. Appl. Environ. Microbiol. 74: 5497-5503 (2008).

Ljung K, Ostin A, Lioussanne L, Sandberg G. Developmental regulation of indole-3-acetic acid turnover in Scots pine seedlings. Plant Physiol. 125: 464-475 (2001).

Loeffler C, Berger S, Guy A, Durand T, Bringmann G, Dreyer M, von Rad U, Durner J, Mueller MJ. B1-phytoprostanes trigger plant defense and detoxification responses. Plant Physiol. 137: 328-340 (2005).

Loguercio LL, Zhang JQ, Wilkins TA. Differential regulation of six novel MYB-domain genes defines two distinct expression patterns in allotetraploid cotton (Gossypium hirsutum L.). Mol. Gen. Genet. 261: 660-671 (1999).

Lopez-Meyer M, Nessler CL. Tryptophan decarboxylase is encoded by two autonomously regulated genes in Camptotheca acuminata which are differentially expressed during development and stress. Plant J. 11: 1167-1175 (1997).

Lu H, Gorman E, McKnight TD. Molecular characterization of two anthranilate synthase alpha subunit genes in Camptotheca acuminata. Planta 221: 352-360 (2005).

Lu H, McKnight TD. Tissue-specific expression of the beta-subunit of tryptophan synthase in Camptotheca acuminata, an indole alkaloid-producing plant. Plant Physiol. 120: 43-52 (1999).

Mantle PG. The role of tryptophan as a biosynthetic precursor of indole-diterpenoid fungal metabolites: continuing a debate. Phytochemistry 70: 7-10 (2009).

Matsuda F, Wakasa K, Miyagawa H. Metabolic flux analysis in plants using dynamic labeling technique: application to tryptophan biosynthesis in cultured rice cells. Phytochemistry 68: 2290-2301 (2007).

Matsuda F, Yamada T, Miyazawa H, Miyagawa H, Wakasa K. Characterization of tryptophan-overproducing potato transgenic for a mutant rice anthranilate synthase alpha-subunit gene (OASA1D). Planta 222: 535-545 (2005).

Matsui K, Miwa K, Sano K. Two single-base-pair substitutions causing desensitization to tryptophan feedback inhibition of anthranilate synthase and enhanced expression of tryptophan genes of Brevibacterium lactofermentum. J. Bacteriol. 169: 5330-5332 (1987).

Matsukawa T, Ishihara A, Iwamura H. Induction of anthranilate synthase activity by elicitors in oats. Z. Naturforsch. [C] 57: 121-128 (2002).

Mayans O, Ivens A, Nissen LJ, Kirschner K, Wilmanns M. Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry. EMBO J. 21: 3245-3254 (2002).

Melanson D, Chilton MD, Masters-Moore D, Chilton WS. A deletion in an indole synthase gene is responsible for the DIMBOA-deficient phenotype of bxbx maize. Proc. Natl. Acad. Sci. U.S.A. 94: 13345-13350 (1997).

Menke FL, Parchmann S, Mueller MJ, Kijne JW, Memelink J. Involvement of the octadecanoid pathway and protein phosphorylation in fungal elicitor-induced expression of terpenoid indole alkaloid biosynthetic genes in Catharanthus roseus. Plant Physiol. 119: 1289-1296 (1999).

Merkl R. Modelling the evolution of the archeal tryptophan synthase. BMC Evol. Biol. 7: 59 (2007).

Michalczuk L, Ribnicky DM, Cooke TJ, Cohen JD. Regulation of indole-3-acetic acid biosynthetic pathways in carrot cell cultures. Plant Physiol. 100: 1346-1353 (1992).

Michel-Reydellet N, Calhoun K, Swartz J. Amino acid stabilization for cell-free protein synthesis by modification of the Escherichia coli genome. Metab. Eng. 6: 197-203 (2004).

Mikkelsen MD, Fuller VL, Hansen BG, Nafisi M, Olsen CE, Nielsen HB, Halkier BA. Controlled indole-3-acetaldoxime production through ethanol-induced expression of CYP79B2. Planta 229: 1209-1217 (2009).

Mikkelsen MD, Hansen CH, Wittstock U, Halkier BA. Cytochrome P450 CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to indole-3-acetaldoxime, a precursor of indole glucosinolates and indole-3-acetic acid. J. Biol. Chem. 275: 33712-33717 (2000).

Miozzari G, Niederberger P, Hutter R. Tryptophan biosynthesis in Saccharomyces cerevisiae: control of the flux through the pathway. J. Bacteriol. 134: 48-59 (1978).

Mobley EM, Kunkel BN, Keith B. Identification, characterization and comparative analysis of a novel chorismate mutase gene in Arabidopsis thaliana. Gene 240: 115-123 (1999).

Morino K, Matsuda F, Miyazawa H, Sukegawa A, Miyagawa H, Wakasa K. Metabolic profiling of tryptophan-overproducing rice calli that express a feedback-insensitive alpha subunit of anthranilate synthase. Plant Cell Physiol. 46: 514-521 (2005).

Mosteller RD. Improved method for measuring the catalytic activity of tryptophan synthase alpha subunit in cell extracts. Biochimie 72: 881-884 (1990).

Muller A, Hillebrand H, Weiler EW. Indole-3-acetic acid is synthesized from L-tryptophan in roots of Arabidopsis thaliana. Planta 206: 362-369 (1998).

Muller A, Weiler EW. IAA-synthase, an enzyme complex from Arabidopsis thaliana catalyzing the formation of indole-3-acetic acid from (S)-tryptophan. Biol. Chem. 381: 679-686 (2000).

Murata J, Luca VD. Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus. Plant J. 44: 581-594 (2005).

Nibeilliu ME, Malthouse JP. The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids. Biochem. J. 381: 847-852 (2004).

Niederberger P, Prasad R, Miozzari G, Kacser H. A strategy for increasing an in vivo flux by genetic manipulations. The tryptophan system of yeast. Biochem. J. 287: 473-479 (1992).

Nishimura T, Mori Y, Furukawa T, Kadota A, Koshiba T. Red light causes a reduction in IAA levels at the apical tip by inhibiting de novo biosynthesis from tryptophan in maize coleoptiles. Planta 224: 1427-1435 (2006).

Niyogi KK, Fink GR. Two anthranilate synthase genes in Arabidopsis: defense-related regulation of the tryptophan pathway. Plant Cell 4: 721-733 (1992).

Niyogi KK, Last RL, Fink GR, Keith B. Suppressors of trp1 fluorescence identify a new Arabidopsis gene, TRP4, encoding the anthranilate synthase beta subunit. Plant Cell 5: 1011-1027 (1993).

Ostin A, Ilic N, Cohen JD. An in vitro system from maize seedlings for tryptophan-independent indole-3-acetic acid biosynthesis. Plant Physiol. 119: 173-178 (1999).

Ouwerkerk PB, Hallard D, Verpoorte R, Memelink J. Identification of UV-B light-responsive regions in the promoter of the tryptophan decarboxylase gene from Catharanthus roseus. Plant Mol. Biol. 41: 491-503 (1999).

Ouwerkerk PB, Memelink J. Elicitor-responsive promoter regions in the tryptophan decarboxylase gene from Catharanthus roseus. Plant Mol. Biol. 39: 129-136 (1999).

Ouyang J, Shao X, Li J. Indole-3-glycerol phosphate, a branchpoint of indole-3-acetic acid biosynthesis from the tryptophan biosynthetic pathway in Arabidopsis thaliana. Plant J. 24: 327-334 (2000).

Pan P, Woehl E, Dunn MF. Protein architecture, dynamics and allostery in tryptophan synthase channeling. Trends Biochem. Sci. 22: 22-27 (1997).

Park WJ, Kriechbaumer V, Muller A, Piotrowski M, Meeley RB, Gierl A, Glawischnig E. The nitrilase ZmNIT2 converts indole-3-acetonitrile to indole-3-acetic acid. Plant Physiol. 133: 794-802 (2003).

Parsons JF, Jensen PY, Pachikara AS, Howard AJ, Eisenstein E, Ladner JE. Structure of Escherichia coli aminodeoxychorismate synthase: Architectural conservation and diversity in chorismate-utilizing enzymes. Biochemistry 41: 2198-2208 (2002).

Pasquali G, Goddijn OJ, de Waal A, Verpoorte R, Schilperoort RA, Hoge JH, Memelink J. Coordinated regulation of two indole alkaloid biosynthetic genes from Catharanthus roseus by auxin and elicitors. Plant Mol. Biol. 18: 1121-1131 (1992).

Pauw B, van Duijn B, Kijne JW, Memelink J. Activation of the oxidative burst by yeast elicitor in Catharanthus roseus cells occurs independently of the activation of genes involved in alkaloid biosynthesis. Plant Mol. Biol. 55: 797-805 (2004).

Payne RJ, Bulloch EM, Abell AD, Abell C. Design and synthesis of aromatic inhibitors of anthranilate synthase. Org. Biomol. Chem. 3: 3629-3635 (2005).

Payne T, Calderone R. Characterization of the phosphoribosylpyrophosphate synthetase gene from Candida albicans. J. Med. Vet. Mycol. 35: 305-312 (1997).

Phillips RS, Dua RK. Indole protects tryptophan indole-lyase, but not tryptophan synthase, from inactivation by trifluoroalanine. Arch. Biochem. Biophys. 296: 489-496 (1992).

Phillips RS, McPhie P, Miles EW, Marchal S, Lange R. Quantitative effects of allosteric ligands and mutations on conformational equilibria in Salmonella typhimurium tryptophan synthase. Arch. Biochem. Biophys. 470: 8-19 (2008).

Pollmann S, Düchting P, Weiler EW. Tryptophan-dependent indole-3-acetic acid biosynthesis by 'IAA-synthase' proceeds via indole-3-acetamide. Phytochemistry 70: 523-531 (2009).

Portmann C, Prestinari C, Myers T, Scharte J, Gademann K. Directed biosynthesis of phytotoxic alkaloids in the cyanobacterium Nostoc 78-12A. Chembiochem. 10: 889-895 (2009).

Prokudina EI, Valeev RYu, Tchuraev RN. A new method for the analysis of the dynamics of the molecular genetic control systems. II. Application of the method of generalized threshold models in the investigation of concrete genetic systems. J. Theor. Biol. 151: 89-110 (1991).

Raboni S, Mozzarelli A, Cook PF. Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium. Biochemistry 46: 13223-13234 (2007).

Radwanski ER, Last RL. Tryptophan biosynthesis and metabolism: biochemical and molecular genetics. Plant Cell 7: 921-934 (1995).

Radwanski ER, Zhao J, Last RL. Arabidopsis thaliana tryptophan synthase alpha: gene cloning, expression, and subunit interaction. Mol. Gen. Genet. 248: 657-667 (1995).

Ramos I, Vivas EI, Downs DM. Mutations in the tryptophan operon allow PurF-independent thiamine synthesis by altering flux in vivo. J. Bacteriol. 190: 815-822 (2008).

Rapparini F, Tam YY, Cohen JD, Slovin JP. Indole-3-acetic acid metabolism in Lemna gibba undergoes dynamic changes in response to growth temperature. Plant Physiol. 128: 1410-1416 (2002).

Rauhut T, Luberacki B, Seitz HU, Glawischnig E. Inducible expression of a Nep1-like protein serves as a model trigger system of camalexin biosynthesis. Phytochemistry 70: 185-189 (2009).

Rekoslavskaya NI, Kuznetsova EV, Vysotskaya EF, Salyaev RK. Tryptophan synthase from Agrobacterium tumefaciens 8628: isolation and properties. Biochemistry (Mosc.) 62: 433-439 (1997).

Renault P, Godon JJ, Goupil N, Delorme C, Corthier G, Ehrlich SD. Metabolic operons in Lactococci. Dev. Biol. Stand. 85: 431-441 (1995).

Rhodes D, Peel GJ, Dudareva N. Metabolism, secondary: engineering pathways of. In (RM Goodman, ed) Encyclopedia of Plant and Crop Science, Marcell Dekker, N.Y., pp. 720-723 (2004).

Ribnicky DM, Cohen JD, Hu WS, Cooke TJ. An auxin surge following fertilization in carrots: a mechanism for regulating plant totipotency. Planta 214: 505-509 (2002).

Rigbers O, Li SM. Ergot alkaloid biosynthesis in Aspergillus fumigatus: overproduction and biochemical characterisation of a 4-dimethylallyltryptophan N-methyltransferase. J. Biol. Chem. 283: 26859-26868 (2008).

Rose AB. The effect of intron location on intron-mediated enhancement of gene expression in Arabidopsis. Plant J. 40: 744-751 (2004).

Rutherford R, Gallois P, Masson PH. Mutations in Arabidopsis thaliana genes involved in the tryptophan biosynthesis pathway affect root waving on tilted agar surfaces. Plant J. 16: 145-154 (1998).

Salvini M, Boccardi TM, Sani E, Bernardi R, Tozzi S, Pugliesi C, Durante M. Alpha-tryptophan synthase of Isatis tinctoria: gene cloning and expression. Plant Physiol. Biochem. 46: 715-723 (2008).

Schardl CL, Panaccione DG, Tudzynski P. Ergot alkaloids - biology and molecular biology. Alkaloids Chem. Biol. 63: 45-86 (2006).

Schlichting I, Yang XJ, Miles EW, Kim AY, Anderson KS. Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase. J. Biol. Chem. 269: 26591-26593 (1994).

Schmid JW, Mauch K, Reuss M, Gilles ED, Kremling A. Metabolic design based on a coupled gene expression-metabolic network model of tryptophan production in Escherichia coli. Metab. Eng. 6: 364-377 (2004).

Schmidt H, Bode R, Birnbaum D. Regulation of the lysine biosynthesis in Pichia guilliermondii. Antonie Van Leeuwenhoek 56: 337-347 (1989).

Schneider B, Knochel T, Darimont B, Hennig M, Dietrich S, Babinger K, Kirschner K, Sterner R. Role of the N-terminal extension of the (betaalpha)8-barrel enzyme indole-3-glycerol phosphate synthase for its fold, stability, and catalytic activity. Biochemistry 44: 16405-16412 (2005).

Schroder P, Abele C, Gohr P, Stuhlfauth-Roisch U, Grosse W. Latest on enzymology of serotonin biosynthesis in walnut seeds. Adv. Exp. Med. Biol. 467: 637-644 (1999).

Schuster S, Dandekar T, Fell DA. Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering. Trends Biotechnol. 17: 53-60 (1999).

Serina L, Blondin C, Krin E, Sismeiro O, Danchin A, Sakamoto H, Gilles AM, Barzu O. Escherichia coli UMP-kinase, a member of the aspartokinase family, is a hexamer regulated by guanine nucleotides and UTP. Biochemistry 34: 5066-5074 (1995).

Shiio I, Sugimoto S. Altered prephenate dehydratase in phenylalanine-excreting mutants of Brevibacterium flavum. J. Biochem. (Tokyo) 79: 173-183 (1976).

Shin M, Mori Y, Kimura A, Fujita Y, Yoshida K, Sano K, Umezawa C. NAD+ biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet. Biochem. Pharmacol. 52: 247-252 (1996).

Shin M, Shinguu T, Sano K, Umezawa C. Metabolic fates of L-tryptophan in Saccharomyces uvarum (Saccharomyces carlsbergensis). Chem. Pharm. Bull. (Tokyo) 39: 1792-1795 (1991).

Siberil Y, Benhamron S, Memelink J, Giglioli-Guivarc'h N, Thiersault M, Boisson B, Doireau P, Gantet P. Catharanthus roseus G-box binding factors 1 and 2 act as repressors of strictosidine synthase gene expression in cell cultures. Plant Mol. Biol. 45: 477-488 (2001).

Singh M, Widholm JM. Study of a corn (Zea mays L.) mutant (blue fluorescent-1) which accumulates anthranilic acid and its beta-glucoside. Biochem. Genet. 13: 357-367 (1975).

Sitbon F, Astot C, Edlund A, Crozier A, Sandberg G. The relative importance of tryptophan-dependent and tryptophan-independent biosynthesis of indole-3-acetic acid in tobacco during vegetative growth. Planta 211: 715-721 (2000).

Skirycz A, Reichelt M, Burow M, Birkemeyer C, Rolcik J, Kopka J, Zanor MI, Gershenzon J, Strnad M, Szopa J, Mueller-Roeber B, Witt I. DOF transcription factor AtDof1.1 (OBP2) is part of a regulatory network controlling glucosinolate biosynthesis in Arabidopsis. Plant J. 47: 10-24 (2006).

Skogman GS, Sjostrom JE. Factors affecting the biosynthesis of L-tryptophan by genetically modified strains of Escherichia coli. J. Gen. Microbiol. 130: 3091-3100 (1984).

Smolen GA, Pawlowski L, Wilensky SE, Bender J. Dominant alleles of the basic helix-loop-helix transcription factor ATR2 activate stress-responsive genes in Arabidopsis. Genetics 161: 1235-1246 (2002).

Speth AR, Hund HK, Lingens F. Terminal phenylalanine and tyrosine biosynthesis of Microtetraspora glauca. Biol. Chem. Hoppe Seyler 370: 591-599 (1989).

Spiteller P, Steglich W. Biosynthesis of 2-aminobenzaldehyde in flowers of Robinia pseudoacacia and Philadelphus coronarius. Phytochemistry 57: 361-363 (2001).

St-Pierre B, Vazquez-Flota FA, De Luca V. Multicellular compartmentation of Catharanthus roseus alkaloid biosynthesis predicts intercellular translocation of a pathway intermediate. Plant Cell 11: 887-900 (1999).

Steenhoudt O, Vanderleyden J. Azospirillum, a free-living nitrogen-fixing bacterium closely associated with grasses: genetic, biochemical and ecological aspects. FEMS Microbiol. Rev. 24: 487-506 (2000).

Tam le T, Eymann C, Antelmann H, Albrecht D, Hecker M. Global gene expression profiling of Bacillus subtilis in response to ammonium and tryptophan starvation as revealed by transcriptome and proteome analysis. J. Mol. Microbiol. Biotechnol. 12: 121-130 (2007).

Tang X, Ezaki S, Fujiwara S, Takagi M, Atomi H, Imanaka T. The tryptophan biosynthesis gene cluster trpCDEGFBA from Pyrococcus kodakaraensis KOD1 is regulated at the transcriptional level and expressed as a single mRNA. Mol. Gen. Genet. 262: 815-821 (1999).

Tang XF, Ezaki S, Atomi H, Imanaka T. Biochemical analysis of a thermostable tryptophan synthase from a hyperthermophilic archaeon. Eur. J. Biochem. 267: 6369-6377 (2000).

Tilby MJ. Tryptophan biosynthesis in Coprinus lagopus: a genetic analysis of mutants. J. Gen. Microbiol. 93: 126-132 (1976).

Tozawa Y, Hasegawa H, Terakawa T, Wakasa K. Characterization of rice anthranilate synthase alpha-subunit genes OASA1 and OASA2. Tryptophan accumulation in transgenic rice expressing a feedback-insensitive mutant of OASA1. Plant Physiol. 126: 1493-1506 (2001).

Tribe DE, Pittard J. Hyperproduction of tryptophan by Escherichia coli: genetic manipulation of the pathways leading to tryptophan formation. Appl. Environ. Microbiol. 38: 181-190 (1979).

Tudzynski P, Holter K, Correia T, Arntz C, Grammel N, Keller U. Evidence for an ergot alkaloid gene cluster in Claviceps purpurea. Mol. Gen. Genet. 261: 133-141 (1999).

Van Ham RCHJ, Gonzalez-Candelas F, Silva FJ, Sabater B, Moya A, Latorre A. Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola. Proc. Natl. Acad. Sci. U.S.A. 97: 10855-10860 (2000).

Venkatesh KV, Bhartiya S, Ruhela A. Multiple feedback loops are key to a robust dynamic performance of tryptophan regulation in Escherichia coli. FEBS Lett. 563: 234-240 (2004).

Vorwerk S, Biernacki S, Hillebrand H, Janzik I, Muller A, Weiler EW, Piotrowski M. Enzymatic characterization of the recombinant Arabidopsis thaliana nitrilase subfamily encoded by the NIT2/NIT1/NIT3-gene cluster. Planta 212: 508-516 (2001).

Wang J, Chen N, Zhang B, Tan Q, Zhang K. Metabolic flux analysis of L-tryptophan biosynthesis. Wei Sheng Wu Xue Bao 43: 473-480 (2003).

Watkins EB, Phillips RS. Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine. Biochemistry 40: 14862-14868 (2001).

Weigent DA, Nester EW. Regulation of histidinol phosphate aminotransferase synthesis by tryptophan in Bacillus subtilis. J. Bacteriol. 128: 202-211 (1976).

Weijers D, Sauer M, Meurette O, Friml J, Ljung K, Sandberg G, Hooykaas P, Offringa R. Maintenance of embryonic auxin distribution for apical-basal patterning by PIN-FORMED-dependent auxin transport in Arabidopsis. Plant Cell 17: 2517-2526 (2005).

Wernegreen JJ, Moran NA. Decay of mutualistic potential in aphid endosymbionts through silencing of biosynthetic loci: Buchnera of Diuraphis. Proc. Roy. Soc. Lond. B. Biol. Sci. 267: 1423-1431 (2000).

Wernegreen JJ, Richardson AO, Moran NA. Parallel acceleration of evolutionary rates in symbiont genes underlying host nutrition. Mol. Phylogenet. Evol. 19: 479-485 (2001).

Weyand M, Schlichting I, Marabotti A, Mozzarelli A. Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase. J. Biol. Chem. 277: 10647-10652 (2002).

Whitmer S, Canel C, Hallard D, Goncalves C, Verpoorte R. Influence of precursor availability on alkaloid accumulation by transgenic cell line of Catharanthus roseus. Plant Physiol. 116: 853-857 (1998).

Wilmanns M, Hyde CC, Davies DR, Kirschner K, Jansonius JN. Structural conservation in parallel beta/alpha-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis. Biochemistry 30: 9161-9169 (1991).

Winn M, Roy AD, Gruschow S, Parameswaran RS, Goss RJ. A convenient one-step synthesis of L-aminotryptophans and improved synthesis of 5-fluorotryptophan. Bioorg. Med. Chem. Lett. 18: 4508-4510 (2008).

Wittstock U, Halkier BA. Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. catalyzes the conversion of L-phenylalanine to phenylacetaldoxime in the biosynthesis of benzylglucosinolate. J. Biol. Chem. 275: 14659-14666 (2000).

Woo YM, Park HJ, Su'udi M, Yang JI, Park JJ, Back K, Park YM, An G. Constitutively wilted 1, a member of the rice YUCCA gene family, is required for maintaining water homeostasis and an appropriate root to shoot ratio. Plant Mol. Biol. 65: 125-136 (2007).

Wood H, Fehlner-Gardner C, Berry J, Fischer E, Graham B, Hackstadt T, Roshick C, McClarty G. Regulation of tryptophan synthase gene expression in Chlamydia trachomatis. Mol. Microbiol. 49: 1347-1359 (2003).

Wright AD, Moehlenkamp CA, Perrot GH, Neuffer MG, Cone KC. The maize auxotrophic mutant orange pericarp is defective in duplicate genes for tryptophan synthase beta. Plant Cell 4: 711-719 (1992).

Xie G, Bonner CA, Jensen RA. A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling. J. Mol. Evol. 49: 108-121 (1999).

Xie G, Brettin TS, Bonner CA, Jensen RA. Mixed-function supraoperons that exhibit overall conservation, albeit shuffled gene organization, across wide intergenomic distances within eubacteria. Microb. Comp. Genomics 4: 5-28 (1999).

Yang XJ, Miles EW. A novel intersubunit repair mechanism in the tryptophan synthase alpha 2 beta 2 complex. Critical role of the beta subunit lysine 167 in intersubunit communication. J. Biol. Chem. 268: 22269-22272 (1993).

Yang XL, Schimmel P, Ewalt KL. Relationship of two human tRNA synthetases used in cell signaling. Trends Biochem. Sci. 29: 250-256 (2004).

Yao K, De Luca V, Brisson N. Creation of a metabolic sink for tryptophan alters the phenylpropanoid pathway and the susceptibility of potato to Phytophthora infestans. Plant Cell 7: 1787-1799 (1995).

Yutani K, Ogasahara K, Tsujita T, Kanemoto K, Matsumoto M, Tanaka S, Miyashita T, Matsushiro A, Sugino Y, Miles EW. Tryptophan synthase alpha subunit glutamic acid 49 is essential for activity. Studies with 19 mutants at position 49. J. Biol. Chem. 262: 13429-13433 (1987).

Zamir LO, Jung E, Jensen RA. Co-accumulation of prephenate, L-arogenate, and spiro-arogenate in a mutant of Neurospora. J. Biol. Chem. 258: 6492-6496 (1983).

Zhang XH, Brotherton JE, Widholm JM, Portis AR Jr. Targeting a nuclear anthranilate synthase alpha-subunit gene to the tobacco plastid genome results in enhanced tryptophan biosynthesis. Return of a gene to its pre-endosymbiotic origin. Plant Physiol. 127: 131-141 (2001).

Zhao J, Last RL. Coordinate regulation of the tryptophan biosynthetic pathway and indolic phytoalexin accumulation in Arabidopsis. Plant Cell 8: 2235-2244 (1996).

Zhao J, Williams CC, Last RL. Induction of Arabidopsis tryptophan pathway enzymes and camalexin by amino acid starvation, oxidative stress, and an abiotic elicitor. Plant Cell 10: 359-370 (1998).

Zhao Y, Hull AK, Gupta NR, Goss KA, Alonso J, Ecker JR, Normanly J, Chory J, Celenza JL. Trp-dependent auxin biosynthesis in Arabidopsis: involvement of cytochrome P450s CYP79B2 and CYP79B3. Genes Dev. 16: 3100-3112 (2002).

Zhou KM, Kohlhaw GB. Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans. J. Biol. Chem. 265: 17409-17412 (1990).

Zook M. Biosynthesis of camalexin from tryptophan pathway intermediates in cell-suspension cultures of Arabidopsis. Plant Physiol. 118: 1389-1393 (1998).

Number of references = 223