Babiak RM, Campello AP, Carnieri EG, Oliveira MB. Methotrexate: pentose cycle and oxidative stress. Cell Biochem. Funct. 16: 283-293 (1998).

Balderas-Hernandez VE, Sabido-Ramos A, Silva P, Cabrera-Valladares N, Hernandez-Chavez G, Baez-Viveros JL, Martinez A, Bolívar F, Gosset G. Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli. Microb. Cell Fact. 8: 19 (2009).

Bender DA. Optimum nutrition: thiamin, biotin and pantothenate. Proc. Nutr. Soc. 58: 427-433 (1999).

Bendt AK, Burkovski A, Schaffer S, Bott M, Farwick M, Hermann T. Towards a phosphoproteome map of Corynebacterium glutamicum. Proteomics 3: 1637-1646 (2003).

Bernacchia G, Schwall G, Lottspeich F, Salamini F, Bartels D. The transketolase gene family of the resurrection plant Craterostigma plantagineum: differential expression during the rehydration phase. EMBO J. 14: 610-618 (1995).

Boren J, Montoya AR, de Atauri P, Comin-Anduix B, Cortes A, Centelles JJ, Frederiks WM, Van Noorden CJ, Cascante M. Metabolic control analysis aimed at the ribose synthesis pathways of tumor cells: a new strategy for antitumor drug development. Mol. Biol. Rep. 29: 7-12 (2002).

Bouvier F, d'Harlingue A, Suire C, Backhaus RA, Camara B. Dedicated roles of plastid transketolases during the early onset of isoprenoid biogenesis in pepper fruits. Plant Physiol. 117: 1423-1431 (1998).

Chandran SS, Yi J, Draths KM, Von Daeniken R, Weber W, Frost JW. Phosphoenolpyruvate availability and the biosynthesis of shikimic acid. Biotechnol. Prog. 19: 808-814 (2003).

Chen L, Spiliotis ET, Roberts MF. Biosynthesis of di-myo-inositol-1,1'-phosphate, a novel osmolyte in hyperthermophilic archaea. J. Bacteriol. 180: 3785-3792 (1998).

de Graaf AA, Striegel K, Wittig RM, Laufer B, Schmitz G, Wiechert W, Sprenger GA, Sahm H. Metabolic state of Zymomonas mobilis in glucose-, fructose-, and xylose-fed continuous cultures as analysed by 13C- and 31P-NMR spectroscopy. Arch. Microbiol. 171: 371-385 (1999).

Edwards JS, Palsson BO. Robustness analysis of the Escherichia coli metabolic network. Biotechnol. Prog. 16: 927-939 (2000).

Eicks M, Maurino V, Knappe S, Flugge UI, Fischer K. The plastidic pentose phosphate translocator represents a link between the cytosolic and the plastidic pentose phosphate pathways in plants. Plant Physiol. 128: 512-522 (2002).

Esakova OA, Meshalkina LE, Golbik R, Hubner G, Kochetov GA. Donor substrate regulation of transketolase. Eur. J. Biochem. 271: 4189-4194 (2004).

Flores N, Xiao J, Berry A, Bolivar F, Valle F. Pathway engineering for the production of aromatic compounds in Escherichia coli. Nat. Biotechnol. 14: 620-623 (1996).

Follstad BD, Stephanopoulos G. Effect of reversible reactions on isotope label redistribution--analysis of the pentose phosphate pathway. Eur. J. Biochem. 252: 360-371 (1998).

Fridlyand LE, Backhausen JE, Scheibe R. Homeostatic regulation upon changes of enzyme activities in the Calvin cycle as an example for general mechanisms of flux control. What can we expect from transgenic plants? Photosynth. Res. 61: 227-239 (1999).

Fridlyand LE, Scheibe R. Regulation of the Calvin cycle for CO2 fixation as an example for general control mechanisms in metabolic cycles. Biosystems 51: 79-93 (1999).

Geiger M, Haake V, Ludewig F, Sonnewald U, Stitt M. The nitrate and ammonium nitrate supply have a major influence on the response of photosynthesis, carbon metabolism, nitrogen metabolism and growth to elevated carbon dioxide in tobacco. Plant Cell Environ. 22: 1177-1199 (1999).

Gerhardt S, Echt S, Busch M, Freigang J, Auerbach G, Bader G, Martin WF, Bacher A, Huber R, Fischer M. Structure and properties of an engineered transketolase from maize. Plant Physiol. 132: 1941-1949 (2003).

Henkes S, Sonnewald U, Badur R, Flachmann R, Stitt M. A small decrease of plastid transketolase activity in antisense tobacco transformants has dramatic effects on photosynthesis and phenylpropanoid metabolism. Plant Cell 13: 535-551 (2001).

Hohmann S, Meacock PA. Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim. Biophys. Acta 1385: 201-219 (1998).

Hurry V, Strand A, Furbank R, Stitt M. The role of inorganic phosphate in the development of freezing tolerance and the acclimatization of photosynthesis to low temperature is revealed by the pho mutants of Arabidopsis thaliana. Plant J. 24: 383-396 (2000).

Hutchings D, Rawsthorne S, Emes MJ. Fatty acid synthesis and the oxidative pentose phosphate pathway in developing embryos of oilseed rape (Brassica napus L.). J. Exp. Bot. 56: 577-585 (2005).

Joshi S, Singh AR, Kumar A, Misra PC, Siddiqi MI, Saxena JK. Molecular cloning and characterization of Plasmodium falciparum transketolase. Mol. Biochem. Parasitol. 160: 32-41 (2008).

Kleijn RJ, van Winden WA, van Gulik WM, Heijnen JJ. Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence. FEBS J. 272: 4970-4982 (2005).

Kromer JO, Sorgenfrei O, Klopprogge K, Heinzle E, Wittmann C. In-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome. J. Bacteriol. 186: 1769-1784 (2004).

Lange BM, Croteau R. Isoprenoid biosynthesis via a mevalonate-independent pathway in plants: cloning and heterologous expression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from peppermint. Arch. Biochem. Biophys. 365: 170-174 (1999).

Lange BM, Wildung MR, McCaskill D, Croteau R. A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. Proc. Natl. Acad. Sci. U.S.A. 95: 2100-2104 (1998).

Lois LM, Campos N, Putra SR, Danielsen K, Rohmer M, Boronat A. Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 95: 2105-2110 (1998).

Martin F, Ramstedt M, Soderhall K. Carbon and nitrogen metabolism in ectomycorrhizal fungi and ectomycorrhizas. Biochimie 69: 569-581 (1987).

Miccheli A, Tomassini A, Puccetti C, Valerio M, Peluso G, Tuccillo F, Calvani M, Manetti C, Conti F. Metabolic profiling by 13C-NMR spectroscopy: [1,2-13C2]glucose reveals a heterogeneous metabolism in human leukemia T cells. Biochimie 88: 437-448 (2006).

Miller B, Heuser T, Zimmer W. A Synechococcus leopoliensis SAUG 1402-1 operon harboring the 1-deoxyxylulose 5-phosphate synthase gene and two additional open reading frames is functionally involved in the dimethylallyl diphosphate synthesis. FEBS Lett. 460: 485-490 (1999).

Mueller C, Schwender J, Zeidler J, Lichtenthaler HK. Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis. Biochem. Soc. Trans. 28: 792-793 (2000).

Ndong C, Danyluk J, Huner NP, Sarhan F. Survey of gene expression in winter rye during changes in growth temperature, irradiance or excitation pressure. Plant Mol. Biol. 45: 691-703 (2001).

Paul MJ, Driscoll SP, Andralojc PJ, Knight JS, Gray JC, Lawlor DW. Decrease of phosphoribulokinase activity by antisense RNA in transgenic tobacco: definition of the light environment under which phosphoribulokinase is not in large excess. Planta 211: 112-119 (2000).

R Poulsen B, Nohr J, Douthwaite S, Hansen LV, Iversen JJ, Visser J, Ruijter GJ. Increased NADPH concentration obtained by metabolic engineering of the pentose phosphate pathway in Aspergillus niger. FEBS J. 272: 1313-1325 (2005).

Rapala-Kozik M, Kowalska E, Ostrowska K. Modulation of thiamine metabolism in Zea mays seedlings under conditions of abiotic stress. J. Exp. Bot. 59: 4133-4143 (2008).

Sauer U, Lasko DR, Fiaux J, Hochuli M, Glaser R, Szyperski T, Wuthrich K, Bailey JE. Metabolic flux ratio analysis of genetic and environmental modulations of Escherichia coli central carbon metabolism. J. Bacteriol. 181: 6679-6688 (1999).

Schaaff-Gerstenschlager I, Zimmermann FK. Pentose-phosphate pathway in Saccharomyces cerevisiae: analysis of deletion mutants for transketolase, transaldolase, and glucose 6-phosphate dehydrogenase. Curr. Genet. 24: 373-376 (1993).

Schaferjohann J, Yoo JG, Kusian B, Bowien B. The cbb operons of the facultative chemoautotroph Alcaligenes eutrophus encode phosphoglycolate phosphatase. J. Bacteriol. 175: 7329-7340 (1993).

Schrader MC, Eskey CJ, Simplaceanu V, Ho C. A carbon-13 nuclear magnetic resonance investigation of the metabolic fluxes associated with glucose metabolism in human erythrocytes. Biochim. Biophys. Acta 1182: 162-178 (1993).

Schuster S, Zevedei-Oancea I. Treatment of multifunctional enzymes in metabolic pathway analysis. Biophys. Chem. 99: 63 (2002).

Schwender J, Ohlrogge JB, Shachar-Hill Y. A flux model of glycolysis and the oxidative pentosephosphate pathway in developing Brassica napus embryos. J. Biol. Chem. 278: 29442-29453 (2003).

Selivanov VA, Meshalkina LE, Solovjeva ON, Kuchel PW, Ramos-Montoya A, Kochetov GA, Lee PW, Cascante M. Rapid simulation and analysis of isotopomer distributions using constraints based on enzyme mechanisms: an example from HT29 cancer cells. Bioinformatics 21: 3558-3564 (2005).

Sprenger GA. Genetics of pentose-phosphate pathway enzymes of Escherichia coli K-12. Arch. Microbiol. 164: 324-330 (1995).

Sprenger GA, Schorken U, Wiegert T, Grolle S, de Graaf AA, Taylor SV, Begley TP, Bringer-Meyer S, Sahm H. Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol. Proc. Natl. Acad. Sci. U.S.A. 94: 12857-12862 (1997).

Sriram G, Fulton DB, Iyer VV, Peterson JM, Zhou R, Westgate ME, Spalding MH, Shanks JV. Quantification of compartmented metabolic fluxes in developing soybean embryos by employing biosynthetically directed fractional 13C labeling, two-dimensional [13C, 1H] nuclear magnetic resonance, and comprehensive isotopomer balancing. Plant Physiol. 136: 3043-3057 (2004).

Tatarko M, Romeo T. Disruption of a global regulatory gene to enhance central carbon flux into phenylalanine biosynthesis in Escherichia coli. Curr. Microbiol. 43: 26-32 (2001).

Van Winden WA, Van Gulik WM, Schipper D, Verheijen PJ, Krabben P, Vinke JL, Heijnen JJ. Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation. Biotechnol. Bioeng. 83: 75-92 (2003).

Wang R, Guegler K, LaBrie ST, Crawford NM. Genomic analysis of a nutrient response in Arabidopsis reveals diverse expression patterns and novel metabolic and potential regulatory genes induced by nitrate. Plant Cell 12: 1491-1510 (2000).

Wang YH, Garvin DF, Kochian LV. Nitrate-induced genes in tomato roots. Array analysis reveals novel genes that may play a role in nitrogen nutrition. Plant Physiol. 127: 345-359 (2001).

Willige BC, Kutzer M, Tebartz F, Bartels D. Subcellular localization and enzymatic properties of differentially expressed transketolase genes isolated from the desiccation tolerant resurrection plant Craterostigma plantagineum. Planta 229: 659-666 (2009).

Wittmann C, Heinzle E. Mass spectrometry for metabolic flux analysis. Biotechnol. Bioeng. 62: 739-750 (1999).

Wittmann C, Heinzle E. Modeling and experimental design for metabolic flux analysis of lysine-producing Corynebacteria by mass spectrometry. Metab. Eng. 3: 173-191 (2001).

Xiang S, Usunow G, Lange G, Busch M, Tong L. Crystal structure of 1-deoxy-D-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis. J. Biol. Chem. 282: 2676-2882 (2007).

Yang X, Liang Z, Wen X, Lu C. Genetic engineering of the biosynthesis of glycinebetaine leads to increased tolerance of photosynthesis to salt stress in transgenic tobacco plants. Plant Mol. Biol. 66: 73-86 (2008).

Number of references = 56