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N Use By Plants
Nitrate Assimilation
Ammonia Assimilation
Glu, Gln, Asn, Gly, Ser
Aminotransferases
Asp, Ala, GABA
Val, Leu, Ileu, Thr, Lys
Pro, Arg, Orn
Polyamines
Non-protein AAs
Alkaloids
Sulfate Assimilation
Cys, Met, AdoMet, ACC
His, Phe, Tyr, Tryp
Secondary Products
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References
HORT640 - Metabolic Plant Physiology

References, threonine dehydratase

Alexander FW, Sandmeier E, Mehta PK, Christen P. Evolutionary relationships among pyridoxal-5'-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families. Eur. J. Biochem. 219: 953-960 (1994).

Arst HN Jr. Some genetical aspects of ornithine metabolism in Aspergillus nidulans. Mol. Gen. Genet. 151: 105-110 (1977).

Bascaran V, Hardisson C, Brana AF. Regulation of nitrogen catabolic enzymes in Streptomyces clavuligerus. J. Gen. Microbiol. 135: 2465-2474 (1989).

Bork P, Rohde K. Sequence similarities between tryptophan synthase beta subunit and other pyridoxal-phosphate-dependent enzymes. Biochem. Biophys. Res. Commun. 171: 1319-1325 (1990).

Burman JD, Harris RL, Hauton KA, Lawson DM, Sawers RG. The iron-sulfur cluster in the L-serine dehydratase TdcG from Escherichia coli is required for enzyme activity. FEBS Lett. 576: 442-444 (2004).

Colon GE, Nguyen TT, Jetten MS, Sinskey AJ, Stephanopoulos G. Production of isoleucine by overexpression of ilvA in a Corynebacterium lactofermentum threonine producer. Appl. Microbiol. Biotechnol. 43: 482-488 (1995).

Cordes C, Mockel B, Eggeling L, Sahm H. Cloning, organization and functional analysis of ilvA, ilvB and ilvC genes from Corynebacterium glutamicum. Gene 112: 113-116 (1992).

Eikmanns BJ, Eggeling L, Sahm H. Molecular aspects of lysine, threonine, and isoleucine biosynthesis in Corynebacterium glutamicum. Antonie Van Leeuwenhoek 64: 145-163 (1993).

Garcia EL, Mourad GS. A site-directed mutagenesis interrogation of the carboxy-terminal end of Arabidopsis thaliana threonine dehydratase/deaminase reveals a synergistic interaction between two effector-binding sites and contributes to the development of a novel selectable … Plant Mol. Biol. 55: 121-134 (2004).

Guillouet S, Rodal AA, An G, Lessard PA, Sinskey AJ. Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl. Environ. Microbiol. 65: 3100-3107 (1999).

Hammer VA, Rogers QR, Freedland RA. Threonine is catabolized by L-threonine 3-dehydrogenase and threonine dehydratase in hepatocytes from domestic cats (Felis domestica). J. Nutr. 126: 2218-2226 (1996).

Hashiguchi K, Takesada H, Suzuki E, Matsui H. Construction of an L-isoleucine overproducing strain of Escherichia coli K-12. Biosci. Biotechnol. Biochem. 63: 672-679 (1999).

Hermann T, Wersch G, Uhlemann EM, Schmid R, Burkovski A. Mapping and identification of Corynebacterium glutamicum proteins by two-dimensional gel electrophoresis and microsequencing. Electrophoresis 19: 3217-3221 (1998).

Hesslinger C, Fairhurst SA, Sawers G. Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate. Mol. Microbiol. 27: 477-492 (1998).

Leoncini R, Vannoni D, Di Pietro MC, Guerranti R, Rosi F, Pagani R, Marinello E. Restoration of rat liver L-threonine dehydratase activity by pyridoxamine 5'-phosphate: the half-transaminating activity of L-threonine dehydratase and its regulatory role. Biochim. Biophys. Acta 1425: 411-418 (1998).

Malumbres M, Mateos LM, Guerrero C, Martin JF. Molecular cloning of the hom-thrC-thrB cluster from Bacillus sp. ULM1: expression of the thrC gene in Escherichia coli and corynebacteria, and evolutionary relationships of the threonine genes. Folia Microbiol. (Praha) 40: 595-606 (1995).

Parsot C. Evolution of biosynthetic pathways: a common ancestor for threonine synthase, threonine dehydratase and D-serine dehydratase. EMBO J. 5: 3013-3019 (1986).

Sahm H, Eggeling L, Eikmanns B, Kramer R. Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum. Ann. N.Y. Acad. Sci. 782: 25-39 (1996).

Sahm H, Eggeling L, Morbach S, Eikmanns B. Construction of L-isoleucine overproducing strains of Corynebacterium glutamicum. Naturwissenschaften 86: 33-38 (1999).

Szamosi I, Shaner DL, Singh BK. Identification and characterization of a biodegradative form of threonine dehydratase in senescing tomato (Lycopersicon esculentum) leaf. Plant Physiol. 101: 999-1004 (1993).

Szamosi IT, Shaner DL, Singh BK. Inhibition of threonine dehydratase is herbicidal. Plant Physiol. 106: 1257-1260 (1994).

Zhao GS, Xia TH, Fischer RS, Jensen RA. Cyclohexadienyl dehydratase from Pseudomonas aeruginosa. Molecular cloning of the gene and characterization of the gene product. J. Biol. Chem. 267: 2487-2493 (1992).

Number of references = 22

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Last Update: 10/01/09