|
HORT640 - Metabolic Plant Physiology
References, mevalonate
Ahn CS, Pai HS. Physiological function of IspE, a plastid MEP pathway gene for isoprenoid biosynthesis, in organelle biogenesis and cell morphogenesis in Nicotiana benthamiana. Plant Mol. Biol. 66: 503-517 (2008).
Alex D, Bach TJ, Chye ML. Expression of Brassica juncea 3-hydroxy-3-methylglutaryl CoA synthase is developmentally regulated and stress-responsive. Plant J. 22: 415-426 (2000).
Anthony JR, Anthony LC, Nowroozi F, Kwon G, Newman JD, Keasling JD. Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene. Metab. Eng. 11: 13-19 (2009).
Arigoni D, Sagner S, Latzel C, Eisenreich W, Bacher A, Zenk MH. Terpenoid biosynthesis from 1-deoxy-D-xylulose in higher plants by intramolecular skeletal rearrangement. Proc. Natl. Acad. Sci. U.S.A. 94: 10600-10605 (1997).
Bajguz A, Asami T. Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris. Planta 218: 869-877 (2004).
Bartram S, Jux A, Gleixner G, Boland W. Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves. Phytochemistry 67: 1661-1672 (2006).
Bede JC, Musser RO, Felton GW, Korth KL. Caterpillar herbivory and salivary enzymes decrease transcript levels of Medicago truncatula genes encoding early enzymes in terpenoid biosynthesis. Plant Mol. Biol. 60: 519-531 (2006).
Bede JC, Teal PE, Goodman WG, Tobe SS. Biosynthetic pathway of insect juvenile hormone III in cell suspension cultures of the sedge Cyperus iria. Plant Physiol. 127: 584-593 (2001).
Begley M, Gahan CG, Kollas AK, Hintz M, Hill C, Jomaa H, Eberl M. The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes. FEBS Lett. 561: 99-104 (2004).
Bouvier F, d'Harlingue A, Suire C, Backhaus RA, Camara B. Dedicated roles of plastid transketolases during the early onset of isoprenoid biogenesis in pepper fruits. Plant Physiol. 117: 1423-1431 (1998).
Burlat V, Oudin A, Courtois M, Rideau M, St-Pierre B. Co-expression of three MEP pathway genes and geraniol 10-hydroxylase in internal phloem parenchyma of Catharanthus roseus implicates multicellular translocation of intermediates during the biosynthesis of monoterpene indole alkaloids… Plant J. 38: 131-141 (2004).
Campos N, Boronat A. Targeting and topology in the membrane of plant 3-hydroxy-3-methylglutaryl coenzyme A reductase. Plant Cell 7: 2163-2174 (1995).
Campos N, Rodriguez-Concepcion M, Sauret-Gueto S, Gallego F, Lois LM, Boronat A. Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. Biochem. J. 353: 59-67 (2001).
Carrie C, Murcha MW, Millar AH, Smith SM, Whelan J. Nine 3-ketoacyl-CoA thiolases (KATs) and acetoacetyl-CoA thiolases (ACATs) encoded by five genes in Arabidopsis thaliana are targeted either to peroxisomes or cytosol but not to mitochondria. Plant Mol. Biol. 63: 97-108 (2007).
Che P, Wurtele ES, Nikolau BJ. Metabolic and environmental regulation of 3-methylcrotonyl-coenzyme A carboxylase expression in Arabidopsis. Plant Physiol. 129: 625-637 (2002).
Cordier H, Karst F, Berges T. Heterologous expression in Saccharomyces cerevisiae of an Arabidopsis thaliana cDNA encoding mevalonate diphosphate decarboxylase. Plant Mol. Biol. 39: 953-967 (1999).
Cvejic JH, Rohmer M. CO2 as main carbon source for isoprenoid biosynthesis via the mevalonate-independent methylerythritol 4-phosphate route in the marine diatoms Phaeodactylum tricornutum and Nitzschia ovalis. Phytochemistry 53: 21-28 (2000).
de Kraker JW, Franssen MC, de Groot A, Konig WA, Bouwmeester HJ. (+)-Germacrene A biosynthesis. The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory. Plant Physiol. 117: 1381-1392 (1998).
De-Eknamkul W, Potduang B. Biosynthesis of beta-sitosterol and stigmasterol in Croton sublyratus proceeds via a mixed origin of isoprene units. Phytochemistry 62: 389-398 (2003).
Disch A, Hemmerlin A, Bach TJ, Rohmer M. Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. Biochem. J. 331: 615-621 (1998).
Dudareva N, Andersson S, Orlova I, Gatto N, Reichelt M, Rhodes D, Boland W, Gershenzon J. The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. Proc. Natl. Acad. Sci. U.S.A. 102: 933-938 (2005).
Dykema PE, Sipes PR, Marie A, Biermann BJ, Crowell DN, Randall SK. A new class of proteins capable of binding transition metals. Plant Mol. Biol. 41: 139-150 (1999).
Eisenreich W, Menhard B, Hylands PJ, Zenk MH, Bacher A. Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin. Proc. Natl. Acad. Sci. U.S.A. 93: 6431-6436 (1996).
Eisenreich W, Rohdich F, Bacher A. Deoxyxylulose phosphate pathway to terpenoids. Trends Plant Sci. 6: 78-84 (2001).
Eisenreich W, Schwarz M, Cartayrade A, Arigoni D, Zenk MH, Bacher A. The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms. Chem. Biol. 5: R221-R233 (1998).
Engprasert S, Taura F, Shoyama Y. Molecular cloning, expression and characterization of recombinant 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Coleus forskohlii Briq. Plant Sci. 169: 287-294 (2005).
Enjuto M, Lumbreras V, Marin C, Boronat A. Expression of the Arabidopsis HMG2 gene, encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase, is restricted to meristematic and floral tissues. Plant Cell 7: 517-527 (1995).
Fellermeier M, Raschke M, Sagner S, Wungsintaweekul J, Schuhr CA, Hecht S, Kis K, Radykewicz T, Adam P, Rohdich F, Eisenreich W, Bacher A, Arigoni D, Zenk MH. Studies on the nonmevalonate pathway of terpene biosynthesis. The role of 2C-methyl-D-erythritol 2,4-cyclodiphosphate in plants. Eur. J. Biochem. 268: 6302-6310 (2001).
Gerber E, Hemmerlin A, Hartmann M, Heintz D, Hartmann MA, Mutterer J, Rodríguez-Concepcion M, Boronat A, Van Dorsselaer A, Rohmer M, Crowell DN, Bach TJ. The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells. Plant Cell 21: 285-300 (2009).
Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W. Retrobiosynthetic nuclear magnetic resonance analysis of amino acid biosynthesis and intermediary metabolism. metabolic flux in developing maize kernels. Plant Physiol. 125: 1178-1186 (2001).
Hahn FM, Hurlburt AP, Poulter CD. Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase. J. Bacteriol. 181: 4499-4504 (1999).
Harada H, Yu F, Okamoto S, Kuzuyama T, Utsumi R, Misawa N. Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli. Appl. Microbiol. Biotechnol. 81: 915-925 (2009).
Hartig K, Beck E. Assessment of lovastatin application as tool in probing cytokinin-mediated cell cycle regulation. Physiol. Plant. 125: 260-267 (2005).
Hong SB, Hughes EH, Shanks JV, San KY, Gibson SI. Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots. Biotechnol. Prog. 19: 1105-1108 (2003).
Hsieh MH, Chang CY, Hsu SJ, Chen JJ. Chloroplast localization of methylerythritol 4-phosphate pathway enzymes and regulation of mitochondrial genes in ispD and ispE albino mutants in Arabidopsis. Plant Mol. Biol. 66: 663-673 (2008).
Hsieh MH, Goodman HM. Functional evidence for the involvement of Arabidopsis IspF homolog in the nonmevalonate pathway of plastid isoprenoid biosynthesis. Planta 223: 779-784 (2006).
Hsieh MH, Goodman HM. The Arabidopsis IspH homolog is involved in the plastid nonmevalonate pathway of isoprenoid biosynthesis. Plant Physiol. 138: 641-653 (2005).
Jain AK, Vincent RM, Nessler CL. Molecular characterization of a hydroxymethylglutaryl-CoA reductase gene from mulberry (Morus alba L.). Plant Mol. Biol. 42: 559-569 (2000).
Jin YS, Stephanopoulos G. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab. Eng. 9: 337-347 (2007).
Jomaa H, Wiesner J, Sanderbrand S, Altincicek B, Weidemeyer C, Hintz M, Turbachova I, Eberl M, Zeidler J, Lichtenthaler HK, Soldati D, Beck E. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science 285: 1573-1576 (1999).
Jones KL, Kim SW, Keasling JD. Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. Metab. Eng. 2: 328-338 (2000).
Kesselmeier J, Staudt M. Biogenic volatile organic compounds (VOC): An overview on emission, physiology and ecology. J. Atmos. Chem. 33: 23-88 (1999).
Khemvong S, Suvachittanont W. Molecular cloning and expression of a cDNA encoding 1-deoxy-D-xylulose-5-phosphate synthase from oil palm Elaeis guineensis Jacq.. Plant Sci. 169: 571-578 (2005).
Kim SW, Keasling JD. Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway in Escherichia coli enhances lycopene production. Biotechnol. Bioeng. 72: 408-415 (2001).
Kizer L, Pitera DJ, Pfleger BF, Keasling JD. Application of functional genomics to pathway optimization for increased isoprenoid production. Appl. Environ. Microbiol. 74: 3229-3241 (2008).
Ko JH, Chow KS, Han KH. Transcriptome analysis reveals novel features of the molecular events occurring in the laticifers of Hevea brasiliensis (para rubber tree). Plant Mol. Biol. 53: 479-492 (2003).
Kreuzwieser J, Schnitzler JP, Steinbrecher R. Biosynthesis of organic compounds emitted by plants. Plant Biol. 1: 149-159 (1999).
Kuzuyama T. Mevalonate and nonmevalonate pathways for the biosynthesis of isoprene units. Biosci. Biotechnol. Biochem. 66: 1619-1627 (2002).
Kuzuyama T, Takahashi S, Seto H. Construction and characterization of Escherichia coli disruptants defective in the yaeM gene. Biosci. Biotechnol. Biochem. 63: 776-778 (1999).
Lange BM, Croteau R. Isoprenoid biosynthesis via a mevalonate-independent pathway in plants: cloning and heterologous expression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from peppermint. Arch. Biochem. Biophys. 365: 170-174 (1999).
Lange BM, Ketchum RE, Croteau RB. Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. Plant Physiol. 127: 305-314 (2001).
Lange BM, Severin K, Bechthold A, Heide L. Regulatory role of microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase for shikonin biosynthesis in Lithospermum erythrorhizon cell suspension cultures. Planta 204: 234-241 (1998).
Lange BM, Wildung MR, McCaskill D, Croteau R. A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. Proc. Natl. Acad. Sci. U.S.A. 95: 2100-2104 (1998).
Learned RM. Light suppresses 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in Arabidopsis thaliana. Plant Physiol. 110: 645-655 (1996).
Leivar P, Gonzalez VM, Castel S, Trelease RN, Lopez-Iglesias C, Arro M, Boronat A, Campos N, Ferrer A, Fernandez-Busquets X. Subcellular localization of Arabidopsis 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Plant Physiol. 137: 57-69 (2005).
Lichtenthaler HK. The 1-deoxy-D-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 50: 47-65 (1999).
Lichtenthaler HK. Non-mevalonate isoprenoid biosynthesis: enzymes, genes and inhibitors. Biochem. Soc. Trans. 28: 785-789 (2000).
Lluch MA, Masferrer A, Arro M, Boronat A, Ferrer A. Molecular cloning and expression analysis of the mevalonate kinase gene from Arabidopsis thaliana. Plant Mol. Biol. 42: 365-376 (2000).
Lois LM, Campos N, Putra SR, Danielsen K, Rohmer M, Boronat A. Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 95: 2105-2110 (1998).
Lois LM, Rodriguez-Concepcion M, Gallego F, Campos N, Boronat A. Carotenoid biosynthesis during tomato fruit development: regulatory role of 1-deoxy-D-xylulose 5-phosphate synthase. Plant J. 22: 503-513 (2000).
Mahmoud SS, Croteau RB. Metabolic engineering of essential oil yield and composition in mint by altering expression of deoxyxylulose phosphate reductoisomerase and menthofuran synthase. Proc. Natl. Acad. Sci. U.S.A. 98: 8915-8920 (2001).
Maldonado-Mendoza IE, Vincent RM, Nessler CL. Molecular characterization of three differentially expressed members of the Camptotheca acuminata 3-hydroxy-3-methylglutaryl CoA reductase (HMGR) gene family. Plant Mol. Biol. 34: 781-790 (1997).
Masse G, Belt ST, Rowland SJ. Biosynthesis of unusual monocyclic alkenes by the diatom Rhizosolenia setigera (Brightwell). Phytochemistry 65: 1101-1106 (2004).
Matthews PD, Wurtzel ET. Metabolic engineering of carotenoid accumulation in Escherichia coli by modulation of the isoprenoid precursor pool with expression of deoxyxylulose phosphate synthase. Appl. Microbiol. Biotechnol. 53: 396-400 (2000).
Meganathan R. Ubiquinone biosynthesis in microorganisms. FEMS Microbiol. Lett. 203: 131-139 (2001).
Milborrow BV. The pathway of biosynthesis of abscisic acid in vascular plants: a review of the present state of knowledge of ABA biosynthesis. J. Exp. Bot. 52: 1145-1164 (2001).
Miller B, Heuser T, Zimmer W. A Synechococcus leopoliensis SAUG 1402-1 operon harboring the 1-deoxyxylulose 5-phosphate synthase gene and two additional open reading frames is functionally involved in the dimethylallyl diphosphate synthesis. FEBS Lett. 460: 485-490 (1999).
Moore KB, Oishi KK. Characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity during maize seed development, germination, and seedling emergence. Plant Physiol. 101: 485-491 (1993).
Mueller C, Schwender J, Zeidler J, Lichtenthaler HK. Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis. Biochem. Soc. Trans. 28: 792-793 (2000).
Munoz-Bertomeu J, Arrillaga I, Ros R, Segura J. Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. Plant Physiol. 142: 890-900 (2006).
Nagata N, Suzuki M, Yoshida S, Muranaka T. Mevalonic acid partially restores chloroplast and etioplast development in Arabidopsis lacking the non-mevalonate pathway. Planta 216: 345-350 (2002).
Nagegowda DA, Ramalingam S, Hemmerlin A, Bach TJ, Chye ML. Brassica juncea HMG-CoA synthase: localization of mRNA and protein. Planta 221: 844-856 (2005).
Nieto B, Fores O, Arro M, Ferrer A. Arabidopsis 3-hydroxy-3-methylglutaryl-CoA reductase is regulated at the post-translational level in response to alterations of the sphingolipid and the sterol biosynthetic pathways. Phytochemistry 70: 53-59 (2009).
Okada K, Kasahara H, Yamaguchi S, Kawaide H, Kamiya Y, Nojiri H, Yamane H. Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. Plant Cell Physiol. 49: 604-616 (2008).
Okada K, Kawaide H, Kuzuyama T, Seto H, Curtis IS, Kamiya Y. Antisense and chemical suppression of the nonmevalonate pathway affects ent-kaurene biosynthesis in Arabidopsis. Planta 215: 339-344 (2002).
Page JE, Hause G, Raschke M, Gao W, Schmidt J, Zenk MH, Kutchan TM. Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing. Plant Physiol. 134: 1401-1413 (2004).
Paseshnichenko VA. A new alternative non-mevalonate pathway for isoprenoid biosynthesis in eubacteria and plants. Biochemistry (Mosc.) 63: 139-148 (1998).
Pfleger BF, Pitera DJ, Newman JD, Martin VJ, Keasling JD. Microbial sensors for small molecules: development of a mevalonate biosensor. Metab. Eng. 9: 30-38 (2007).
Pitera DJ, Paddon CJ, Newman JD, Keasling JD. Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli. Metab. Eng. 9: 193-207 (2007).
Proteau PJ. Biosynthesis of phytol in the cyanobacterium Synechocystis sp. UTEX 2470: utilization of the non-mevalonate pathway. J. Nat. Prod. 61: 841-843 (1998).
Puan KJ, Wang H, Dairi T, Kuzuyama T, Morita CT. fldA is an essential gene required in the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. FEBS Lett. 579: 3802-3806 (2005).
Rangasamy D, Ratledge C. Compartmentation of ATP:citrate lyase in plants. Plant Physiol. 122: 1225-1230 (2000).
Schwender J, Gemunden C, Lichtenthaler HK. Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids. Planta 212: 416-423 (2001).
Schwender J, Muller C, Zeidler J, Lichtenthaler HK. Cloning and heterologous expression of a cDNA encoding 1-deoxy-D-xylulose-5-phosphate reductoisomerase of Arabidopsis thaliana. FEBS Lett. 455: 140-144 (1999).
Schwender J, Seemann M, Lichtenthaler HK, Rohmer M. Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus. Biochem. J. 316: 73-80 (1996).
Schwender J, Zeidler J, Groner R, Muller C, Focke M, Braun S, Lichtenthaler FW, Lichtenthaler HK. Incorporation of 1-deoxy-D-xylulose into isoprene and phytol by higher plants and algae. FEBS Lett. 414: 129-134 (1997).
Suzuki M, Nakagawa S, Kamide Y, Kobayashi K, Ohyama K, Hashinokuchi H, Kiuchi R, Saito K, Muranaka T, Nagata N. Complete blockage of the mevalonate pathway results in male gametophyte lethality. J. Exp. Bot. 60: 2055-2064 (2009).
Takahashi S, Kuzuyama T, Watanabe H, Seto H. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 95: 9879-9884 (1998).
Tambasco-Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick TB. Vitamin B6 biosynthesis in higher plants. Proc. Natl. Acad. Sci. U.S.A. 102: 13687-13692 (2005).
Uchida H, Sugiyama R, Nakayachi O, Takemura M, Ohyama K. Expression of the gene for sterol-biosynthesis enzyme squalene epoxidase in parenchyma cells of the oil plant, Euphorbia tirucalli. Planta 226: 1109-1115 (2007).
Vaupotic T, Plemenitas A. Osmoadaptation-dependent activity of microsomal HMG-CoA reductase in the extremely halotolerant black yeast Hortaea werneckii is regulated by ubiquitination. FEBS Lett. 581: 3391-3395 (2007).
Wagner WP, Helmig D, Fall R. Isoprene biosynthesis in Bacillus subtilis via the methylerythritol phosphate pathway. J. Nat. Prod. 63: 37-40 (2000).
Walter MH, Fester T, Strack D. Arbuscular mycorrhizal fungi induce the non-mevalonate methylerythritol phosphate pathway of isoprenoid biosynthesis correlated with accumulation of the 'yellow pigment' and other apocarotenoids. Plant J. 21: 571-578 (2000).
Wang YD, Wu JC, Yuan YJ. Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. Cell Biol. Int. 31: 1179-1183 (2007).
Wentzinger LF, Bach TJ, Hartmann MA. Inhibition of squalene synthase and squalene epoxidase in tobacco cells triggers an up-regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Plant Physiol. 130: 334-346 (2002).
Wolff M, Seemann M, Bui BTS, Frapart Y, Tritsch D, Estrabot AG, Rodriguez-Concepcion M, Boronat A, Marquet A, Rohmer M. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. FEBS Lett. 541: 115-120 (2003).
Xiang S, Usunow G, Lange G, Busch M, Tong L. Crystal structure of 1-deoxy-D-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis. J. Biol. Chem. 282: 2676-2882 (2007).
Xie Z, Kapteyn J, Gang DR. A systems biology investigation of the MEP/terpenoid and shikimate/phenylpropanoid pathways points to multiple levels of metabolic control in sweet basil glandular trichomes. Plant J. 54: 349-361 (2008).
Yamazaki Y, Kitajima M, Arita M, Takayama H, Sudo H, Yamazaki M, Aimi N, Saito K. Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-13C]glucose. Plant Physiol. 134: 161-170 (2004).
Zahiri HS, Yoon SH, Keasling JD, Lee SH, Won Kim S, Yoon SC, Shin YC. Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. Metab. Eng. 8: 406-416 (2006).
Zeidler J, Lichtenthaler HK. Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation. Planta 213: 323-326 (2001).
Zhong JJ, Yue CJ. Plant cells: secondary metabolite heterogeneity and its manipulation. Adv. Biochem. Eng. Biotechnol. 100: 53-88 (2005).
Number of references = 102
| PubMed Search | Entrez Protein Search | ISI Web of Knowledge Search | Scirus Search |
|