Abe I, Utsumi Y, Oguro S, Noguchi H. The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide. FEBS Lett. 562: 171-176 (2004).

Allen RH, Stabler SP, Savage DG, Lindenbaum J. Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency. FASEB J. 7: 1344-1353 (1993).

Azachi M, Sadka A, Fisher M, Goldshlag P, Gokhman I, Zamir A. Salt induction of fatty acid elongase and membrane lipid modifications in the extreme halotolerant alga Dunaliella salina. Plant Physiol. 129: 1320-1329 (2002).

Bao W, Sheldon PJ, Hutchinson CR. Purification and properties of the Streptomyces peucetius DpsC beta-ketoacyl:acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis. Biochemistry 38: 9752-9757 (1999).

Bao X, Pollard M, Ohlrogge J. The biosynthesis of erucic acid in developing embryos of Brassica rapa. Plant Physiol. 118: 183-190 (1998).

Baud S, Guyon V, Kronenberger J, Wuilleme S, Miquel M, Caboche M, Lepiniec L, Rochat C. Multifunctional acetyl-CoA carboxylase 1 is essential for very long chain fatty acid elongation and embryo development in Arabidopsis. Plant J. 33: 75-86 (2003).

Bederman IR, Kasumov T, Reszko AE, David F, Brunengraber H, Kelleher JK. In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver. J. Biol. Chem. 279: 43217-43226 (2004).

Beerhues L. Hyperforin. Phytochemistry 67: 2201-2207 (2006).

Chandler RJ, Aswani V, Tsai MS, Falk M, Wehrli N, Stabler S, Allen R, Sedensky M, Kazazian HH, Venditti CP. Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism. Mol. Genet. Metab. 89: 64-73 (2006).

Chohnan S, Furukawa H, Fujio T, Nishihara H, Takamura Y. Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. Appl. Environ. Microbiol. 63: 553-560 (1997).

Chohnan S, Izawa H, Nishihara H, Takamura Y. Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses. Biosci. Biotechnol. Biochem. 62: 1122-1128 (1998).

Dobson CM, Gradinger A, Longo N, Wu X, Leclerc D, Lerner-Ellis J, Lemieux M, Belair C, Watkins D, Rosenblatt DS, Gravel RA. Homozygous nonsense mutation in the MCEE gene and siRNA suppression of methylmalonyl-CoA epimerase expression: a novel cause of mild methylmalonic aciduria. Mol. Genet. Metab. 88: 327-333 (2006).

Eisenreich W, Strauss G, Werz U, Fuchs G, Bacher A. Retrobiosynthetic analysis of carbon fixation in the phototrophic eubacterium Chloroflexus aurantiacus. Eur. J. Biochem. 215: 619-632 (1993).

Falk KL, Guerra DJ. Coenzyme A biosynthesis in plants: partial purification and characterization of pantothenate kinase from spinach. Arch. Biochem. Biophys. 301: 424-430 (1993).

Fujiwara H, Tanaka Y, Fukui Y, Nakao M, Ashikari T, Kusumi T. Anthocyanin 5-aromatic acyltransferase from Gentiana triflora. Purification, characterization and its role in anthocyanin biosynthesis. Eur. J. Biochem. 249: 45-51 (1997).

Fukui T, Suzuki M, Tsuge T, Nakamura S. Microbial synthesis of poly((R)-3-hydroxybutyrate-co-3-hydroxypropionate) from unrelated carbon sources by engineered Cupriavidus necator. Biomacromolecules 10: 700-706 (2009).

Ghanevati M, Jaworski JG. Engineering and mechanistic studies of the Arabidopsis FAE1 beta-ketoacyl-CoA synthase, FAE1 KCS. Eur. J. Biochem. 269: 3531-3539 (2002).

Goese M, Kammhuber K, Bacher A, Zenk MH, Eisenreich W. Biosynthesis of bitter acids in hops. A 13C-NMR and 2H-NMR study on the building blocks of humulone. Eur. J. Biochem. 263: 447-454 (1999).

Grice K, Lu H, Zhou Y, Stuart-Williams H, Farquhar GD. Biosynthetic and environmental effects on the stable carbon isotopic compositions of anteiso-(3-methyl) and iso-(2-methyl) alkanes in tobacco leaves. Phytochemistry 69: 2807-2814 (2008).

Halvorsen O, Skrede S. Regulation of the biosynthesis of CoA at the level of pantothenate kinase. Eur. J. Biochem. 124: 211-215 (1982).

Hugler M, Krieger RS, Jahn M, Fuchs G. Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation. Eur. J. Biochem. 270: 736-744 (2003).

Jackowski S, Rock CO. Consequences of reduced intracellular coenzyme A content in Escherichia coli. J. Bacteriol. 166: 866-871 (1986).

Jindaprasert A, Springob K, Schmidt J, De-Eknamkul W, Kutchan TM. Pyrone polyketides synthesized by a type III polyketide synthase from Drosophyllum lusitanicum. Phytochemistry 69: 3043-3053 (2008).

Junghanns KT, Kneusel RE, Groger D, Matern U. Differential regulation and distribution of acridone synthase in Ruta graveolens. Phytochemistry 49: 403-411 (1998).

Khosla C, Gokhale RS, Jacobsen JR, Cane DE. Tolerance and specificity of polyketide synthases. Annu. Rev. Biochem. 68: 219-253 (1999).

Klaus D, Ohlrogge JB, Neuhaus HE, Dormann P. Increased fatty acid production in potato by engineering of acetyl-CoA carboxylase. Planta 219: 389-396 (2004).

Kuate SP, Padua RM, Eisenbeiss WF, Kreis W. Purification and characterization of malonyl-coenzyme A: 21-hydroxypregnane 21-O-malonyltransferase (Dp21MaT) from leaves of Digitalis purpurea L. Phytochemistry 69: 619-626 (2008).

Lau J, Fu H, Cane DE, Khosla C. Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units. Biochemistry 38: 1643-1651 (1999).

Lessire R, Chevalier S, Lucet-Levannier K, Lellouche JP, Mioskowski C, Cassagne C. Study of the 3-hydroxy eicosanoyl-coenzyme A dehydratase and (E)-2,3 enoyl-coenzyme A reductase involved in acyl-coenzyme A elongation in etiolated leek seedlings. Plant Physiol. 119: 1009-1016 (1999).

Liu B, Beuerle T, Klundt T, Beerhues L. Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia. Planta 218: 492-496 (2004).

Liu B, Falkenstein-Paul H, Schmidt W, Beerhues L. Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: cDNA cloning, functional expression, and site-directed mutagenesis of two polyketide synthases. Plant J. 34: 847-855 (2003).

Liu B, Raeth T, Beuerle T, Beerhues L. Biphenyl synthase, a novel type III polyketide synthase. Planta 225: 1495-1503 (2007).

Ma LQ, Guo YW, Gao DY, Ma DM, Wang YN, Li GF, Liu BY, Wang H, Ye HC. Identification of a Polygonum cuspidatum three-intron gene encoding a type III polyketide synthase producing both naringenin and p-hydroxybenzalacetone. Planta 229: 1077-1086 (2009).

Martens JH, Barg H, Warren MJ, Jahn D. Microbial production of vitamin B12. Appl. Microbiol. Biotechnol. 58: 275-285 (2002).

Menendez C, Bauer Z, Huber H, Gad'on N, Stetter KO, Fuchs G. Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation. J. Bacteriol. 181: 1088-1098 (1999).

Metz JG, Kuner J, Rosenzweig B, Lippmeier JC, Roessler P, Zirkle R. Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids. Plant Physiol. Biochem. 47: 472-478 (2009).

Morita H, Noguchi H, Schroder J, Abe I. Novel polyketides synthesized with a higher plant stilbene synthase. Eur. J. Biochem. 268: 3759-3766 (2001).

Nishimaki T, Yamanaka H, Mizugaki M. Acetyl-CoA-dependent chain elongation of fatty acids in Escherichia coli K-12. J. Biochem. (Tokyo) 99: 365-374 (1986).

Ozeki Y, Sakano K, Komamine A, Tanaka Y, Noguchi H, Sankawa U, Suzuki T. Purification and some properties of chalcone synthase from a carrot suspension culture induced for anthocyanin synthesis and preparation of its specific antiserum. J. Biochem. (Tokyo) 98: 9-17 (1985).

Paizs C, Diemer T, Retey J. The putative coenzyme B(12)-dependent methylmalonyl-CoA mutase from potatoes is a phosphatase. Bioorg. Chem. 36: 261-264 (2008).

Paolacci AR, D'Ovidio R, Marabottini R, Nali C, Lorenzini G, Abenavoli MR, Badiani M. Ozone induces a differential accumulation of phenyalanine ammonia-lyase, chalcone synthase and chalcone isomerase RNA transcripts in sensitive and resistant bean cultivars. Aust. J. Plant Physiol. 28: 425-428 (2001).

Preisig-Muller R, Schwekendiek A, Brehm I, Reif HJ, Kindl H. Characterization of a pine multigene family containing elicitor-responsive stilbene synthase genes. Plant Mol. Biol. 39: 221-229 (1999).

Qin YM, Pujol FM, Hu CY, Feng JX, Kastaniotis AJ, Hiltunen JK, Zhu YX. Genetic and biochemical studies in yeast reveal that the cotton fibre-specific GhCER6 gene functions in fatty acid elongation. J. Exp. Bot. 58: 473-481 (2007).

Rajgarhia VB, Priestley ND, Strohl WR. The product of dpsC confers starter unit fidelity upon the daunorubicin polyketide synthase of Streptomyces sp. strain C5. Metab. Eng. 3: 49-63 (2001).

Reeves AR, Cernota WH, Brikun IA, Wesley RK, Mark Weber J. Engineering precursor flow for increased erythromycin production in Aeromicrobium erythreum. Metab. Eng. 6: 300-312 (2004).

Riedel B, Fiskerstrand T, Refsum H, Ueland PM. Co-ordinate variations in methylmalonyl-CoA mutase and methionine synthase, and the cobalamin cofactors in human glioma cells during nitrous oxide exposure and the subsequent recovery phase. Biochem. J. 341: 133-138 (1999).

Rock CO, Karim MA, Zhang YM, Jackowski S. The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes. Gene 291: 35-43 (2002).

Samappito S, Page J, Schmidt J, De-Eknamkul W, Kutchan TM. Molecular characterization of root-specific chalcone synthases from Cassia alata. Planta 216: 64-71 (2002).

Sasaki Y, Nagano Y. Plant acetyl-CoA carboxylase: structure, biosynthesis, regulation, and gene manipulation for plant breeding. Biosci. Biotechnol. Biochem. 68: 1175-1184 (2004).

Savvi S, Warner DF, Kana BD, McKinney JD, Mizrahi V, Dawes SS. Functional characterization of a vitamin B12-dependent methylmalonyl pathway in Mycobacterium tuberculosis: implications for propionate metabolism during growth on fatty acids. J. Bacteriol. 190: 3886-3895 (2008).

Schujman GE, Guerin M, Buschiazzo A, Schaeffer F, Llarrull LI, Reh G, Vila AJ, Alzari PM, de Mendoza D. Structural basis of lipid biosynthesis regulation in Gram-positive bacteria. EMBO J. 25: 4074-4083 (2006).

Subrahmanyam S, Cronan JE Jr. Overproduction of a functional fatty acid biosynthetic enzyme blocks fatty acid synthesis in Escherichia coli. J. Bacteriol. 180: 4596-4602 (1998).

Suormala T, Baumgartner MR, Coelho D, Zavadakova P, Koich V, Koch HG, Berghauser M, Wraith JE, Burlina A, Sewell A, Herwig J, Fowler B. The cblD defect causes either isolated or combined deficiency of methylcobalamin and adenosylcobalamin synthesis. J. Biol. Chem. 279: 42742-42749 (2004).

Suzuki H, Sawada S, Watanabe K, Nagae S, Yamaguchi MA, Nakayama T, Nishino T. Identification and characterization of a novel anthocyanin malonyltransferase from scarlet sage (Salvia splendens) flowers: an enzyme that is phylogenetically separated from other anthocyanin acyltransferases. Plant J. 38: 994-1003 (2004).

Takamura Y, Nomura G. Changes in the intracellular concentration of acetyl-CoA and malonyl-CoA in relation to the carbon and energy metabolism of Escherichia coli K12. J. Gen. Microbiol. 134: 2249-2253 (1988).

Traufeller K, Gellerich FN, Zierz S. Different sensitivities of CPT I and CPT II for inhibition by L-aminocarnitine in human skeletal muscle. Biochim. Biophys. Acta 1608: 149-154 (2004).

Vrijbloed JW, Zerbe-Burkhardt K, Ratnatilleke A, Grubelnik-Leiser A, Robinson JA. Insertional inactivation of methylmalonyl coenzyme A (CoA) mutase and isobutyryl-CoA mutase genes in Streptomyces cinnamonensis: influence on polyketide antibiotic biosynthesis. J. Bacteriol. 181: 5600-5605 (1999).

Wattanachaisaereekul S, Lantz AE, Nielsen ML, Nielsen J. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. Metab. Eng. 10: 246-254 (2008).

Witkowski A, Joshi AK, Lindqvist Y, Smith S. Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine. Biochemistry 38: 11643-1150 (1999).

Yanai Y, Kawasaki T, Shimada H, Wurtele ES, Nikolau BJ, Ichikawa N. Genomic organization of 251 kDa acetyl-CoA carboxylase genes in Arabidopsis: tandem gene duplication has made two differentially expressed isozymes. Plant Cell Physiol. 36: 779-787 (1995).

Yao X, Soden C Jr, Summers MF, Beckett D. Comparison of the backbone dynamics of the apo- and holo-carboxy-terminal domain of the biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase. Protein Sci. 8: 307-317 (1999).

Yu XH, Chen MH, Liu CJ. Nucleocytoplasmic-localized acyltransferases catalyze the malonylation of 7-O-glycosidic (iso)flavones in Medicago truncatula. Plant J. 55: 382-396 (2008).

Zhang W, Jiang W, Zhao G, Yang Y, Chiao J. Sequence analysis and expression of the aspartokinase and aspartate semialdehyde dehydrogenase operon from rifamycin SV-producing Amycolatopsis mediterranei. Gene 237: 413-419 (1999).

Number of references = 63