Affek HP, Yakir D. Natural abundance carbon isotope composition of isoprene reflects incomplete coupling between isoprene synthesis and photosynthetic carbon flow. Plant Physiol. 131: 1727-1736 (2003).

Arigoni D, Eisenreich W, Latzel C, Sagner S, Radykewicz T, Zenk MH, Bacher A. Dimethylallyl pyrophosphate is not the committed precursor of isopentenyl pyrophosphate during terpenoid biosynthesis from 1-deoxyxylulose in higher plants. Proc. Natl. Acad. Sci. U.S.A. 96: 1309-1314 (1999).

Arigoni D, Sagner S, Latzel C, Eisenreich W, Bacher A, Zenk MH. Terpenoid biosynthesis from 1-deoxy-D-xylulose in higher plants by intramolecular skeletal rearrangement. Proc. Natl. Acad. Sci. U.S.A. 94: 10600-10605 (1997).

Botella-Pavia P, Besumbes O, Phillips MA, Carretero-Paulet L, Boronat A, Rodriguez-Concepcion M. Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. Plant J. 40: 188-199 (2004).

Brandle JE, Richman A, Swanson AK, Chapman BP. Leaf ESTs from Stevia rebaudiana: a resource for gene discovery in diterpene synthesis. Plant Mol. Biol. 50: 613-622 (2002).

Carretero-Paulet L, Cairo A, Botella-Pavia P, Besumbes O, Campos N, Boronat A, Rodriguez-Concepcion M. Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase. Plant Mol. Biol. 62: 683-695 (2006).

De-Eknamkul W, Potduang B. Biosynthesis of beta-sitosterol and stigmasterol in Croton sublyratus proceeds via a mixed origin of isoprene units. Phytochemistry 62: 389-398 (2003).

Eisenreich W, Rohdich F, Bacher A. Deoxyxylulose phosphate pathway to terpenoids. Trends Plant Sci. 6: 78-84 (2001).

Eisenreich W, Schwarz M, Cartayrade A, Arigoni D, Zenk MH, Bacher A. The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms. Chem. Biol. 5: R221-R233 (1998).

Estevez JM, Cantero A, Romero C, Kawaide H, Jimenez LF, Kuzuyama T, Seto H, Kamiya Y, Leon P. Analysis of the expression of CLA1, a gene that encodes the 1-deoxyxylulose 5-phosphate synthase of the 2-C-methyl-D-erythritol-4-phosphate pathway in Arabidopsis. Plant Physiol. 124: 95-104 (2000).

Fellermeier M, Eisenreich W, Bacher A, Zenk MH. Biosynthesis of cannabinoids. Incorporation experiments with 13C-labeled glucoses. Eur. J. Biochem. 268: 1596-1604 (2001).

Goese M, Kammhuber K, Bacher A, Zenk MH, Eisenreich W. Biosynthesis of bitter acids in hops. A 13C-NMR and 2H-NMR study on the building blocks of humulone. Eur. J. Biochem. 263: 447-454 (1999).

Hirschberg J. Carotenoid biosynthesis in flowering plants. Curr. Opin. Plant Biol. 4: 210-218 (2001).

Hoeffler JF, Tritsch D, Grosdemange-Billiard C, Rohmer M. Isoprenoid biosynthesis via the methylerythritol phosphate pathway. Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. Eur. J. Biochem. 269: 4446-4457 (2002).

Karl T, Fall R, Rosenstiel TN, Prazeller P, Larsen B, Seufert G, Lindinger W. On-line analysis of the 13CO2 labeling of leaf isoprene suggests multiple subcellular origins of isoprene precursors. Planta 215: 894-905 (2002).

Kutrzeba L, Dayan FE, Howell J, Feng J, Giner JL, Zjawiony JK. Biosynthesis of salvinorin A proceeds via the deoxyxylulose phosphate pathway. Phytochemistry 68: 1872-1881 (2007).

Lange BM, Croteau R. Isoprenoid biosynthesis via a mevalonate-independent pathway in plants: cloning and heterologous expression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from peppermint. Arch. Biochem. Biophys. 365: 170-174 (1999).

Lois LM, Campos N, Putra SR, Danielsen K, Rohmer M, Boronat A. Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 95: 2105-2110 (1998).

Mahmoud SS, Croteau RB. Metabolic engineering of essential oil yield and composition in mint by altering expression of deoxyxylulose phosphate reductoisomerase and menthofuran synthase. Proc. Natl. Acad. Sci. U.S.A. 98: 8915-8920 (2001).

Matthews PD, Wurtzel ET. Metabolic engineering of carotenoid accumulation in Escherichia coli by modulation of the isoprenoid precursor pool with expression of deoxyxylulose phosphate synthase. Appl. Microbiol. Biotechnol. 53: 396-400 (2000).

McCaskill D, Croteau R. Isopentenyl diphosphate is the terminal product of the deoxyxylulose-5-phosphate pathway for terpenoid biosynthesis in plants. Tetrahedron Lett. 40: 653-656 (1999).

Miller B, Heuser T, Zimmer W. A Synechococcus leopoliensis SAUG 1402-1 operon harboring the 1-deoxyxylulose 5-phosphate synthase gene and two additional open reading frames is functionally involved in the dimethylallyl diphosphate synthesis. FEBS Lett. 460: 485-490 (1999).

Mueller C, Schwender J, Zeidler J, Lichtenthaler HK. Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis. Biochem. Soc. Trans. 28: 792-793 (2000).

Romer S, Lubeck J, Kauder F, Steiger S, Adomat C, Sandmann G. Genetic engineering of a zeaxanthin-rich potato by antisense inactivation and co-suppression of carotenoid epoxidation. Metab. Eng. 4: 263-272 (2002).

Schnitzler JP, Graus M, Kreuzwieser J, Heizmann U, Rennenberg H, Wisthaler A, Hansel A. Contribution of different carbon sources to isoprene biosynthesis in poplar leaves. Plant Physiol. 135: 152-160 (2004).

Schwender J, Gemunden C, Lichtenthaler HK. Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids. Planta 212: 416-423 (2001).

Sharkey TD, Chen X, Yeh S. Isoprene increases thermotolerance of fosmidomycin-fed leaves. Plant Physiol. 125: 2001-2006 (2001).

Sharkey TD, Yeh S. Isoprene emission from plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 52: 407-436 (2001).

Sprenger GA, Schorken U, Wiegert T, Grolle S, de Graaf AA, Taylor SV, Begley TP, Bringer-Meyer S, Sahm H. Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol. Proc. Natl. Acad. Sci. U.S.A. 94: 12857-12862 (1997).

Tambasco-Studart M, Tews I, Amrhein N, Fitzpatrick TB. Functional analysis of PDX2 from Arabidopsis, a glutaminase involved in vitamin B6 biosynthesis. Plant Physiol. 144: 915-925 (2007).

Tambasco-Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick TB. Vitamin B6 biosynthesis in higher plants. Proc. Natl. Acad. Sci. U.S.A. 102: 13687-13692 (2005).

Walter MH, Fester T, Strack D. Arbuscular mycorrhizal fungi induce the non-mevalonate methylerythritol phosphate pathway of isoprenoid biosynthesis correlated with accumulation of the 'yellow pigment' and other apocarotenoids. Plant J. 21: 571-578 (2000).

Wiberley AE, Donohue AR, Westphal MM, Sharkey TD. Regulation of isoprene emission from poplar leaves throughout a day. Plant Cell Environ. 32: 939-947 (2009).

Wolfertz M, Sharkey TD, Boland W, Kuhnemann F. Rapid regulation of the methylerythritol 4-phosphate pathway during isoprene synthesis. Plant Physiol. 135: 1939-1945 (2004).

Wolfertz M, Sharkey TD, Boland W, Kuhnemann F, Yeh S, Weise SE. Biochemical regulation of isoprene emission. Plant Cell Environ. 26: 1357-1364 (2003).

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