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N Use By Plants
Nitrate Assimilation
Ammonia Assimilation
Glu, Gln, Asn, Gly, Ser
Aminotransferases
Asp, Ala, GABA
Val, Leu, Ileu, Thr, Lys
Pro, Arg, Orn
Polyamines
Non-protein AAs
Alkaloids
Sulfate Assimilation
Cys, Met, AdoMet, ACC
His, Phe, Tyr, Tryp
Secondary Products
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References
HORT640 - Metabolic Plant Physiology

References, aspartate decarboxylase

Albert A, Dhanaraj V, Genschel U, Khan G, Ramjee MK, Pulido R, Sibanda BL, von Delft F, Witty M, Blundell TL, Smith AG, Abell C 1998 Crystal structure of aspartate decarboxylase at 2.2 A resolution provides evidence for an ester in protein self-processing. Nat. Struct. Biol. 5: 289-293.

Castillo RM, Mizuguchi K, Dhanaraj V, Albert A, Blundell TL, Murzin AG 1999 A six-stranded double-psi beta barrel is shared by several protein superfamilies. Structure Fold. Des. 7: 227-236.

Chopra S, Pai H, Ranganathan A 2002 Expression, purification, and biochemical characterization of Mycobacterium tuberculosis aspartate decarboxylase, PanD. Protein Expr. Purif. 25: 533-540.

Condon S, Collins JK, O'donovan GA 1976 Regulation of arginine and pyrimidine biosynthesis in Pseudomonas putida. J. Gen. Microbiol. 92: 375-383.

Cremer J, Treptow C, Eggeling L, Sahm H 1988 Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum. J. Gen. Microbiol. 134: 3221-3229.

Cronan JE Jr 1980 Beta-alanine synthesis in Escherichia coli. J. Bacteriol. 141: 1291-1297.

Cronan JE Jr, Littel KJ, Jackowski S 1982 Genetic and biochemical analyses of pantothenate biosynthesis in Escherichia coli and Salmonella typhimurium. J. Bacteriol. 149: 916-922.

Dusch N, P hler A, Kalinowski J 1999 Expression of the Corynebacterium glutamicum panD gene encoding L-aspartate-alpha-decarboxylase leads to pantothenate overproduction in Escherichia coli. Appl. Environ. Microbiol. 65: 1530-1539.

Fouad WM, Rathinasabapathi B 2006 Expression of bacterial L-aspartate-alpha-decarboxylase in tobacco increases beta-alanine and pantothenate levels and improves thermotolerance. Plant Mol. Biol. 60: 495-505.

Fouad WM, Rathinasabapathi B 2006 Expression of bacterial L-aspartate-alpha-decarboxylase in tobacco increases beta-alanine and pantothenate levels and improves thermotolerance. Plant Mol. Biol. 60: 495-505.

Gluck MR, Thomas RG, Davis KL, Haroutunian V 2002 Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. Am. J. Psychiat. 159: 1165-1173.

Graber R, Kasper P, Malashkevich VN, Sandmeier E, Berger P, Gehring H, Jansonius JN, Christen P 1995 Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme. Eur. J. Biochem. 232: 686-690.

Graber R, Kasper P, Malashkevich VN, Strop P, Gehring H, Jansonius JN, Christen P 1999 Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation. J. Biol. Chem. 274: 31203-31208.

Isupov MN, Antson AA, Dodson EJ, Dodson GG, Dementieva IS, Zakomirdina LN, Wilson KS, Dauter Z, Lebedev AA, Harutyunyan EH 1998 Crystal structure of tryptophanase. J. Mol. Biol. 276: 603-623.

Johannessen CU, Qu H, Sonnewald U, Hassel L, Fonnum F 2001 Estimation of aspartate synthesis in GABAergic neurons in mice by C-13 NMR spectroscopy. Neuroreport 12: 3729-3732.

Katahira R, Ashihara H 2002 Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers. Planta 215: 821-828.

Khristoforov RR, Sukhareva BS, Dixon HB, Sparkes MJ, Krasnov VP, Bukrina IM 1995 The interaction of glutamate decarboxylase from Escherichia coli with substrate analogues modified at C-3 and C-4. Biochem. Mol. Biol. Int. 36: 77-85.

Kochhar S, Mehta PK, Christen P 1989 Assay for aliphatic amino acid decarboxylases by high-performance liquid chromatography. Anal. Biochem. 179: 182-185.

Kwon AR, Lee BI, Han BW, Ahn HJ, Yang JK, Yoon HJ, Suh SW 2002 Crystallization and preliminary X-ray crystallographic analysis of aspartate 1-decarboxylase from Helicobacter pylori. Acta Crystallogr. D. Biol. Crystallogr. 58: 861-863.

Mehta PK, Christen P 1994 Homology of 1-aminocyclopropane-1-carboxylate synthase, 8-amino-7-oxononanoate synthase, 2-amino-6-caprolactam racemase, 2,2-dialkylglycine decarboxylase, glutamate-1-semialdehyde 2,1-aminomutase ... with aminotransferases. Biochem. Biophys. Res. Commun. 198: 138-143.

Mehta PK, Christen P 2000 The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes. Adv. Enzymol. Relat. Areas Mol. Biol. 74: 129-184.

Morgunov I, Srere PA 1998 Interaction between citrate synthase and malate dehydrogenase. Substrate channeling of oxaloacetate. J. Biol. Chem. 273: 29540-29544.

Novitskaya L, Trevanion SJ, Driscoll S, Foyer CH, Noctor G 2002 How does photorespiration modulate leaf amino acid contents? A dual approach through modelling and metabolite analysis. Plant Cell Environ. 25: 821-835.

Ottenhof HH, Ashurst JL, Whitney HM, Saldanha SA, Schmitzberger F, Gweon HS, Blundell TL, Abell C, Smith AG 2004 Organisation of the pantothenate (vitamin B5) biosynthesis pathway in higher plants. Plant J. 37: 61-72.

Pascarella S, Schirch V, Bossa F 1993 Similarity between serine hydroxymethyltransferase and other pyridoxal phosphate-dependent enzymes. FEBS Lett. 331: 145-149.

Qu K, Martin DL, Lawrence CE 1998 Motifs and structural fold of the cofactor binding site of human glutamate decarboxylase. Protein Sci. 7: 1092-1105.

Ramjee MK, Genschel U, Abell C, Smith AG 1997 Escherichia coli L-aspartate-alpha-decarboxylase: preprotein processing and observation of reaction intermediates by electrospray mass spectrometry. Biochem. J. 323: 661-669.

Scapin G, Blanchard JS 1998 Enzymology of bacterial lysine biosynthesis. Adv. Enzymol. Relat. Areas Mol. Biol. 72: 279-324.

Sherwin AL 1999 Neuroactive amino acids in focally epileptic human brain: a review. Neurochem. Res. 24: 1387-1395.

Takahashi N, Yamada T 2000 Pathways for amino acid metabolism by Prevotella intermedia and Prevotella nigrescens. Oral Microbiol. Immunol. 15: 96-102.

Tolbert WD, Zhang Y, Cottet SE, Bennett EM, Ekstrom JL, Pegg AE, Ealick SE 2003 Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant. Biochemistry 42: 2386-2395.

Vacca RA, Christen P, Malashkevich VN, Jansonius JN, Sandmeier E 1995 Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity. Eur. J. Biochem. 227: 481-487.

Williamson JM, Brown GM 1979 Purification and properties of L-aspartate-alpha-decarboxylase, an enzyme that catalyzes the formation of beta-alanine in Escherichia coli. J. Biol. Chem. 254: 8074-8082.

Number of references = 33

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