Abdelmalek MF, Angulo P, Jorgensen RA, Sylvestre PB, Lindor KD. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am. J. Gastroenterol. 96: 2711-2717 (2001).

Abel S, Nguyen MD, Chow W, Theologis A. ACS4, a primary indoleacetic acid-responsive gene encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis thaliana. Structural characterization, expression in Escherichia coli, and expression characteristics in response to auxin. J. Biol. Chem. 270: 19093-19099 (1995).

Abraham DG, Cooper AJ. Cloning and expression of a rat kidney cytosolic glutamine transaminase K that has strong sequence homology to kynurenine pyruvate aminotransferase. Arch. Biochem. Biophys. 335: 311-320 (1996).

Ahmad I, Hellebust JA. A spectrophotometric procedure for measuring oxoglutarate and determining aminotransferase activities using nicotinamide adenine dinucleotide phosphate-linked glutamate dehydrogenase from algae. Anal. Biochem. 180: 99-104 (1989).

Ahmad S, Jensen RA. A simple spectrophotometric assay for arogenate dehydratase. Anal. Biochem. 163: 107-111 (1987).

Ajayi OB, Odutuga A. Effect of low-zinc status and essential fatty acids deficiency on the activities of aspartate aminotransferase and alanine aminotransferase in liver and serum of albino rats. Nahr. Food 48: 88-90 (2004).

Akama K, Akihiro T, Kitagawa M, Takaiwa F. Rice (Oryza sativa) contains a novel isoform of glutamate decarboxylase that lacks an authentic calmodulin-binding domain at the C-terminus. Biochim. Biophys. Acta 1522: 143-150 (2001).

Alawady AE, Grimm B. Tobacco Mg protoporphyrin IX methyltransferase is involved in inverse activation of Mg porphyrin and protoheme synthesis. Plant J. 41: 282-290 (2005).

Alexander FW, Sandmeier E, Mehta PK, Christen P. Evolutionary relationships among pyridoxal-5'-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families. Eur. J. Biochem. 219: 953-960 (1994).

Allison G, Gough K, Rogers L, Smith A. A suicide vector for allelic recombination involving the gene for glutamate 1-semialdehyde aminotransferase in the cyanobacterium Synechococcus PCC 7942. Mol. Gen. Genet. 255: 392-399 (1997).

Almo SC, Smith DL, Danishefsky AT, Ringe D. The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli. Protein Eng. 7: 405-412 (1994).

Andruszkiewicz R, Silverman RB. 4-Amino-3-alkylbutanoic acids as substrates for gamma-aminobutyric acid aminotransferase. J. Biol. Chem. 265: 22288-22291 (1990).

Arai R, Nishimoto M, Toyama M, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S. Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase. Biochim. Biophys. Acta. 1750: 40-47 (2005).

Armengaud P, Thiery L, Buhot N, Grenier-De March G, Savoure A. Transcriptional regulation of proline biosynthesis in Medicago truncatula reveals developmental and environmental specific features. Physiol. Plant. 120: 442-450 (2004).

Arruda P, Kemper EL, Papes F, Leite A. Regulation of lysine catabolism in higher plants. Trends Plant Sci. 5: 324-330 (2000).

Aubert S, Bligny R, Douce R, Gout E, Ratcliffe RG, Roberts JK. Contribution of glutamate dehydrogenase to mitochondrial glutamate metabolism studied by 13C and 31P nuclear magnetic resonance. J. Exp. Bot. 52: 37-45 (2001).

Azzariti A, Vacca RA, Giannattasio S, Merafina RS, Marra E, Doonan S. Kinetic properties and thermal stabilities of mutant forms of mitochondrial aspartate aminotransferase. Biochim. Biophys. Acta 1386: 29-38 (1998).

Bae HS, Im WT, Suwa Y, Lee JM, Lee ST, Chang YK. Characterization of diverse heterocyclic amine-degrading denitrifying bacteria from various environments. Arch. Microbiol. 191: 329-340 (2009).

Bago B, Pfeffer PE, Abubaker J, Jun J, Allen JW, Brouillette J, Douds DD, Lammers PJ, Shachar-Hill Y. Carbon export from arbuscular mycorrhizal roots involves the translocation of carbohydrate as well as lipid. Plant Physiol. 131: 1496-1507 (2003).

Bao J, Lee S, Chen C, Zhang X, Zhang Y, Liu S, Clark T, Wang J, Cao M, Yang H, Wang SM, Yu J. Serial analysis of gene expression study of a hybrid rice strain (LYP9) and its parental cultivars. Plant Physiol. 138: 1216-1231 (2005).

Barel I, MacDonald DW. Enzyme defects in glutamate-requiring strains of Schizosaccharomyces pombe. FEMS Microbiol. Lett. 113: 267-272 (1993).

Barjaktarovic Z, Schutz W, Madlung J, Fladerer C, Nordheim A, Hampp R. Changes in the effective gravitational field strength affect the state of phosphorylation of stress-related proteins in callus cultures of Arabidopsis thaliana. J. Exp. Bot. 60: 779-789 (2009).

Barthelmess IB. Regulation of amino acid synthetic enzymes in Neurospora crassa in the presence of high concentrations of amino acids. Mol. Gen. Genet. 203: 533-537 (1986).

Bartsch K, von Johnn-Marteville A, Schulz A. Molecular analysis of two genes of the Escherichia coli gab cluster: nucleotide sequence of the glutamate:succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD). J. Bacteriol. 172: 7035-7042 (1990).

Bascaran V, Hardisson C, Brana AF. Regulation of nitrogen catabolic enzymes in Streptomyces clavuligerus. J. Gen. Microbiol. 135: 2465-2474 (1989).

Basmaison O, Rolland MO, Cochat P, Bozon D. Identification of 5 novel mutations in the AGXT gene. Hum. Mutat. 15: 577 (2000).

Basurko MJ, Marche M, Darriet M, Cassaigne A. Phosphoserine aminotransferase, the second step-catalyzing enzyme for serine biosynthesis. IUBMB Life 48: 525-529 (1999).

Baumberg S, Harwood CR. Carbon and nitrogen repression of arginine catabolic enzymes in Bacillus subtilis. J. Bacteriol. 137: 189-196 (1979).

Bedell JP, Chalot M, Garnier A, Botton B. Effects of nitrogen source on growth and activity of nitrogen-assimilating enzymes in Douglas-fir seedlings. Tree Physiol. 19: 205-210 (1999).

Belhumeur P, Fortin N, Clark MW. A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase. Yeast 10: 385-389 (1994).

Bennett FI, Jackson AA. Glycine is not formed through the amino transferase reaction in human or rat placenta. Placenta 19: 329-331 (1998).

Berry A, Jensen RA, Hendry AT. Enzymic arrangement and allosteric regulation of the aromatic amino acid pathway in Neisseria gonorrhoeae. Arch. Microbiol. 149: 87-94 (1987).

Beudeker RF, Tabita FR. Control of photorespiratory glycolate metabolism in an oxygen-resistant mutant of Chlorella sorokiniana. J. Bacteriol. 155: 650-656 (1983).

Bibiano Melo JF, Lundstedt LM, Meton I, Baanante IV, Moraes G. Effects of dietary levels of protein on nitrogenous metabolism of Rhamdia quelen (Teleostei: Pimelodidae). Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 145: 181-187 (2006).

Birdsey GM, Danpure CJ. Evolution of alanine:glyoxylate aminotransferase intracellular targeting: structural and functional analysis of the guinea pig gene. Biochem. J. 331: 49-60 (1998).

Birolo L, Dal Piaz F, Pucci P, Marino G. Structural characterization of the M* partly folded intermediate of wild type and P138A aspartate aminotransferase from Escherichia coli. J. Biol. Chem. 277: 17428-17437 (2002).

Birolo L, Malashkevich VN, Capitani G, De Luca F, Moretta A, Jansonius JN, Marino G. Functional and structural analysis of cis-proline mutants of Escherichia coli aspartate aminotransferase. Biochemistry 38: 905-913 (1999).

Birolo L, Tutino ML, Fontanella B, Gerday C, Mainolfi K, Pascarella S, Sannia G, Vinci F, Marino G. Aspartate aminotransferase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC 125. Cloning, expression, properties, and molecular modelling. Eur. J. Biochem. 267: 2790-2802 (2000).

Bishop GR, Zhu Z, Whitehead TL, Hicks RP, Davidson VL. Identification of reaction products and intermediates of aromatic-amine dehydrogenase by 15N and 13C NMR. Biochem. J. 330: 1159-1163 (1998).

Bishop K, Gough K, Mahoney S, Smith A, Rogers L. Synechococcus mutants resistant to an enamine mechanism inhibitor of glutamate-1-semialdehyde aminotransferase. FEBS Lett. 450: 57-60 (1999).

Blessinger KJ, Tunnicliff G. Kinetics of inactivation of 4-aminobutyrate aminotransferase by 3-bromopyruvate. Biochem. Cell Biol. 70: 716-719 (1992).

Bonarius HP, Houtman JH, de Gooijer CD, Tramper J, Schmid G. Activity of glutamate dehydrogenase is increased in ammonia-stressed hybridoma cells. Biotechnol. Bioeng. 57: 447-453 (1998).

Bonner C, Jensen R. Prephenate aminotransferase. Methods Enzymol. 142: 479-487 (1987).

Bonner CA, Fischer RS, Ahmad S, Jensen RA. Remnants of an ancient pathway to L-phenylalanine and L-tyrosine in enteric bacteria: evolutionary implications and biotechnological impact. Appl. Environ. Microbiol. 56: 3741-3747 (1990).

Bonner CA, Jensen RA. Novel features of prephenate aminotransferase from cell cultures of Nicotiana silvestris. Arch. Biochem. Biophys. 238: 237-246 (1985).

Bono H, Ogata H, Goto S, Kanehisa M. Reconstruction of amino acid biosynthesis pathways from the complete genome sequence. Genome Res. 8: 203-210 (1998).

Boon L, Geerts WJ, Jonker A, Lamers WH, Van Noorden CJ. High protein diet induces pericentral glutamate dehydrogenase and ornithine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules. Histochem. Cell Biol. 111: 445-452 (1999).

Bossa F, Maras B, De Biase D, John RA, Barra D. Sequence studies on pyridoxal phosphate-dependent enzymes. Biotechnol. Appl. Biochem. 18: 143-148 (1993).

Bourgis F, Roje S, Nuccio ML, Fisher DB, Tarczynski MC, Li C, Herschbach C, Rennenberg H, Pimenta MJ, Shen TL, Gage DA, Hanson AD. S-Methylmethionine plays a major role in phloem sulfur transport and is synthesized by a novel type of methyltransferase. Plant Cell 11: 1485-1498 (1999).

Bozzo GG, Colman B, Matsuda Y. Active transport of CO2 and bicarbonate is induced in response to external CO(2) concentration in the green alga Chlorella kessleri. J. Exp. Bot. 51: 1341-1348 (2000).

Bradbury MW, Berk PD. Mitochondrial aspartate aminotransferase: direction of a single protein with two distinct functions to two subcellular sites does not require alternative splicing of the mRNA. Biochem. J. 345: 423-427 (2000).

Bray JE, Todd AE, Pearl FM, Thornton JM, Orengo CA. The CATH Dictionary of Homologous Superfamilies (DHS): a consensus approach for identifying distant structural homologues. Protein Eng. 13: 153-165 (2000).

Breitkreuz KE, Shelp BJ. Subcellular compartmentation of the 4-aminobutyrate shunt in protoplasts from developing soybean cotyledons. Plant Physiol. 108: 99-103 (1995).

Buc PS, Rolfes RJ. ade9 is an allele of SER1 and plays an indirect role in purine biosynthesis. Yeast 15: 1347-1355 (1999).

Buentello JA, Gatlin DM. Plasma citrulline and arginine kinetics in juvenile channel catfish, Ictalurus punctatus, given oral gabaculine. Fish Physiol. Biochem. 24: 105-112 (2001).

Bughio N, Nakanishi H, Kiyomiya S, Matsuhashi S, Ishioka NS, Watanabe S, Uchida H, Tsuji A, Osa A, Kume T, Hashimoto S, Sekine T, Mori S. Real-time [11C]methionine translocation in barley in relation to mugineic acid phytosiderophore biosynthesis. Planta 213: 708-715 (2001).

Byng GS, Whitaker RJ, Shapiro CL, Jensen RA. The aromatic amino acid pathway branches at L-arogenate in Euglena gracilis. Mol. Cell Biol. 1: 426-438 (1981).

Canas RA, Villalobos DP, Diaz-Moreno SM, Canovas FM, Canton FR. Molecular and functional analyses support a role of ornithine-delta-aminotransferase in the provision of glutamate for glutamine biosynthesis during pine germination. Plant Physiol. 148: 77-88 (2008).

Capitani G, Hohenester E, Feng L, Storici P, Kirsch JF, Jansonius JN. Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene. J. Mol. Biol. 294: 745-756 (1999).

Carpe AI, Smith IK. Serine-glyoxylate aminotransferase from kidney bean (Phaseolus vulgaris). II. The reverse reactions. Biochim. Biophys. Acta 370: 96-101 (1974).

Chang YC, Lee TM. High temperature-induced free proline accumulation in Gracilaria tenuistipitata (Rhodophyta). Bot. Bul. Acad. Sin. 40: 289-294 (1999).

Chapple CCS, Glover JR, Ellis BE. Purification and characterization of methionine:glyoxylate aminotransferase from Brassica carinata and Brassica napus. Plant Physiol. 94: 1887-1896 (1990).

Chatziioannou A, Palaiologos G, Kolisis FN. Metabolic flux analysis as a tool for the elucidation of the metabolism of neurotransmitter glutamate. Metab. Eng. 5: 201-210 (2003).

Chen CT, Chen LM, Lin CC, Kao CH. Regulation of proline accumulation in detached rice leaves exposed to excess copper. Plant Sci. 160: 283-290 (2001).

Chen S, Hofius D, Sonnewald U, Bornke F. Temporal and spatial control of gene silencing in transgenic plants by inducible expression of double-stranded RNA. Plant J. 36: 731-740 (2003).

Chen W, Wright L, Li S, Cosloy SD, Russell CS. Expression of glutamyl-tRNA reductase in Escherichia coli. Biochim. Biophys. Acta 1309: 109-121 (1996).

Chen ZY, Burow MD, Mason CB, Moroney JV. A low-CO2-inducible gene encoding an alanine: alpha-ketoglutarate aminotransferase in Chlamydomonas reinhardtii. Plant Physiol. 112: 677-684 (1996).

Chia YC, Smith GW, Lees GJ. Differences in properties between aromatic amino acid: aromatic keto acid aminotransferases and aromatic amino acid: alpha-ketoglutarate aminotransferases. Life Sci. 34: 2443-2452 (1984).

Chico E, Olavarria JS, Nunez de Castro I. L-Alanine as an end product of glycolysis in Saccharomyces cerevisiae growing under different hypoxic conditions. Antonie Van Leeuwenhoek 44: 193-201 (1978).

Chistoserdova LV, Lidstrom ME. Genetics of the serine cycle in Methylobacterium extorquens AM1: identification of sgaA and mtdA and sequences of sgaA, hprA, and mtdA. J. Bacteriol. 176: 1957-1968 (1994).

Choi SY, Churchich JE. 4-Aminobutyrate aminotransferase. Conformational changes induced by reduction of pyridoxal 5-phosphate. Biochim. Biophys. Acta 830: 120-126 (1985).

Choi SY, Churchich JE. Biosynthesis of 4-aminobutyrate aminotransferase. Eur. J. Biochem. 161: 289-294 (1986).

Chopra J, Kaur N, Gupta AK. The role of ammonium assimilating enzymes in lentil roots and nodules. Biol. Plant. 47: 105-109 (2003).

Christie A, Butler M. The adaptation of bhk cells to a non-ammoniagenic glutamate-based culture medium. Biotechnol. Bioeng. 64: 298-309 (1999).

Chung YL, Rider LG, Bell JD, Summers RM, Zemel LS, Rennebohm RM, Passo MH, Hicks J, Miller FW, Scott DL; Juvenile Dermatomyositis Disease Activity Collaborative Study Group. Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies. Arthritis Rheum. 53: 565-570 (2005).

Churchich JE. 4-Aminobutyrate aminotransferase. Different susceptibility to inhibitors, microenvironment of the cofactor binding site and distance of the catalytic sites. Eur. J. Biochem. 126: 507-511 (1982).

Churchich JE, Moses U. 4-Aminobutyrate aminotransferase. The presence of nonequivalent binding sites. J. Biol. Chem. 256: 1101-1104 (1981).

Collins N, Merrett MJ. The localization of glycollate-pathway enzymes in Euglena. Biochem. J. 148: 321-328 (1975).

Connelly JA, Conn EE. Tyrosine biosynthesis in Sorghum bicolor: isolation and regulatory properties of arogenate dehydrogenase. Z. Naturforsch. [C] 41: 69-78 (1986).

Contador CA, Rizk ML, Asenjo JA, Liao JC. Ensemble modeling for strain development of L-lysine-producing Escherichia coli. Metab. Eng. 11: 221-233 (2009).

Contestabile R, John RA. The mechanism of high-yielding chiral syntheses catalysed by wild-type and mutant forms of aspartate aminotransferase. Eur. J. Biochem. 240: 150-155 (1996).

Contestabile R, Paiardini A, Pascarella S, di Salvo ML, D'Aguanno S, Bossa F. L-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subgroup of strictly related enzymes specialized for different functions. Eur. J. Biochem. 268: 6508-6525 (2001).

Cooper AJL. The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. Neurochem. Int. 44: 557-577 (2004).

Cox RJ, Schouten JA, Stentiford RA, Wareing KJ. Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. Bioorg. Med. Chem. Lett. 8: 945-950 (1998).

Cronin CN, Kirsch JF. Role of arginine-292 in the substrate specificity of aspartate aminotransferase as examined by site-directed mutagenesis. Biochemistry 27: 4572-4579 (1988).

Csonka LN, Ikeda TP, Fletcher SA, Kustu S. The accumulation of glutamate is necessary for optimal growth of Salmonella typhimurium in media of high osmolality but not induction of the proU operon. J. Bacteriol. 176: 6324-6333 (1994).

Cybis J, Davis RH. Organization and control in the arginine biosynthetic pathway of Neurospora. J. Bacteriol. 123: 196-202 (1975).

da Cunha A. Purification, characterization and induction of L-phenylalanine ammonia-lyase in Phaseolus vulgaris. Eur. J. Biochem. 178: 243-248 (1988).

Danishefsky AT, Onnufer JJ, Petsko GA, Ringe D. Activity and structure of the active-site mutants R386Y and R386F of Escherichia coli aspartate aminotransferase. Biochemistry 30: 1980-1985 (1991).

Danpure CJ. The molecular basis of alanine: glyoxylate aminotransferase mistargeting: the most common single cause of primary hyperoxaluria type 1. J. Nephrol. 11: 8-12 (1998).

Danpure CJ. Primary hyperoxaluria type 1 and peroxisome-to-mitochondrion mistargeting of alanine:glyoxylate aminotransferase. Biochimie 75: 309-315 (1993).

Danpure CJ, Purdue PE, Fryer P, Griffiths S, Allsop J, Lumb MJ, Guttridge KM, Jennings PR, Scheinman JI, Mauer SM, et al. Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation. Am. J. Hum. Genet. 53: 417-432 (1993).

Davis BG. Chemical modification of biocatalysts. Curr. Opin. Biotechnol. 14: 379-386 (2003).

Davoodi J, Drown PM, Bledsoe RK, Wallin R, Reinhart GD, Hutson SM. Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferases. J. Biol. Chem. 273: 4982-4989 (1998).

de la Torre F, De Santis L, Suarez MF, Crespillo R, Canovas FM. Identification and functional analysis of a prokaryotic-type aspartate aminotransferase: implications for plant amino acid metabolism. Plant J. 46: 414-425 (2006).

de la Torre F, Moya-Garcia AA, Suarez MF, Rodriguez-Caso C, Canas RA, Sanchez-Jimenez F, Canovas FM. Molecular modeling and site-directed mutagenesis reveal essential residues for catalysis in a prokaryote-type aspartate aminotransferase. Plant Physiol. 149: 1648-1660 (2009).

de la Torre F, Suarez MF, Santis L, Canovas FM. The aspartate aminotransferase family in conifers: biochemical analysis of a prokaryotic-type enzyme from maritime pine. Tree Physiol. 27: 1283-1291 (2007).

Deborde C, Rolin DB, Boyaval P. In vivo 13C NMR study of the bidirectional reactions of the Wood-Werkman cycle and around the pyruvate node in Propionibacterium freudenreichii subsp. shermanii and Propionibacterium acidipropionici. Metab. Eng. 1: 309-319 (1999).

Dekaney CM, Wu G, Jaeger LA. Ornithine aminotransferase messenger RNA expression and enzymatic activity in fetal porcine intestine. Pediatr. Res. 50: 104-109 (2001).

Delauney AJ, Hu CA, Kishor PB, Verma DP. Cloning of ornithine delta-aminotransferase cDNA from Vigna aconitifolia by trans-complementation in Escherichia coli and regulation of proline biosynthesis. J. Biol. Chem. 268: 18673-18678 (1993).

Denessiouk KA, Denesyuk AI, Lehtonen JV, Korpela T, Johnson MS. Common structural elements in the architecture of the cofactor-binding domains in unrelated families of pyridoxal phosphate-dependent enzymes. Proteins 35: 250-261 (1999).

Der Garabedian PA, Lotti AM, Vermeersch JJ. 4-Aminobutyrate:2-oxoglutarate aminotransferase from Candida. Purification and properties. Eur. J. Biochem. 156: 589-596 (1986).

Dever LV, Blackwell RD, Fullwood NJ, Lacuesta M, Leegood RC, Onek LA, Pearson M, Lea PJ. The isolation and characterization of mutants of the C4 photosynthetic pathway. J. Exp. Bot. 46: 1363-1376 (1995).

Devi MT, Raghavendra AS. Partial reduction in activities of photorespiratory enzymes in C3-C4 intermediates of Alternanthera and Parthenium. J. Exp. Bot. 44: 779-784 (1993).

Dolzan M, Johansson K, Roig-Zamboni V, Campanacci V, Tegoni M, Schneider G, Cambillau C. Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function. FEBS Lett. 571: 141-146 (2004).

Drsata J. Tryptophan metabolism via transamination. In vitro aminotransferase assay using dinitrophenylhydrazine method. Adv. Exp. Med. Biol. 527: 511-517 (2003).

Dry IB, Dimitriadis E, Ward AD, Wiskich JT. The photorespiratory hydrogen shuttle. Synthesis of phthalonic acid and its use in the characterization of the malate/aspartate shuttle in pea (Pisum sativum) leaf mitochondria. Biochem. J. 245: 669-675 (1987).

Ducreux LJ, Morris WL, Prosser IM, Morris JA, Beale MH, Wright F, Shepherd T, Bryan GJ, Hedley PE, Taylor MA. Expression profiling of potato germplasm differentiated in quality traits leads to the identification of candidate flavour and texture genes. J. Exp. Bot. 59: 4219-4231 (2008).

Duncan K, Coggins JR. The serC-aro A operon of Escherichia coli. A mixed function operon encoding enzymes from two different amino acid biosynthetic pathways. Biochem. J. 234: 49-57 (1986).

Eads JC, Beeby M, Scapin G, Yu TW, Floss HG. Crystal structure of 3-amino-5-hydroxybenzoic acid (AHBA) synthase. Biochemistry 38: 9840-9849 (1999).

Eden A, Benvenisty N. Characterization of a branched-chain amino-acid aminotransferase from Schizosaccharomyces pombe. Yeast 14: 189-194 (1998).

Ehlting J, Mattheus N, Aeschliman DS, Li E, Hamberger B, Cullis IF, Zhuang J, Kaneda M, Mansfield SD, Samuels L, Ritland K, Ellis BE, Bohlmann J, Douglas CJ. Global transcript profiling of primary stems from Arabidopsis thaliana identifies candidate genes for missing links in lignin biosynthesis and transcriptional regulators of fiber differentiation. Plant J. 42: 618-640 (2005).

El Malki F, Frankard V, Jacobs M. Molecular cloning and expression of a cDNA sequence encoding histidinol phosphate aminotransferase from Nicotiana tabacum. Plant Mol. Biol. 37: 1013-1022 (1998).

El Malki F, Jacobs M. Molecular characterization and expression study of a histidine auxotrophic mutant (his1-) of Nicotiana plumbaginifolia. Plant Mol. Biol. 45: 191-199 (2001).

Endo S, Ishiguro S, Tamai M. Possible mechanism for the decrease of mitochondrial aspartate aminotransferase activity in ischemic and hypoxic rat retinas. Biochim. Biophys. Acta 1450: 385-396 (1999).

Erecinska M, Nelson D, Nissim I, Daikhin Y, Yudkoff M. Cerebral alanine transport and alanine aminotransferase reaction: alanine as a source of neuronal glutamate. J. Neurochem. 62: 1953-1964 (1994).

Famiani F, Walker RP, Tecsi L, Chen ZH, Proietti P, Leegood RC. An immunohistochemical study of the compartmentation of metabolism during the development of grape (Vitis vinifera L.) berries. J. Exp. Bot. 51: 675-683 (2000).

Faure M, Glomot F, Bledsoe R, Hutson S, Papet I. Purification and cloning of the mitochondrial branched-chain amino acid aminotransferase from sheep placenta. Eur. J. Biochem. 259: 104-111 (1999).

Feild MJ, Nguyen DC, Armstrong FB. Amino acid sequence of Salmonella typhimurium branched-chain amino acid aminotransferase. Biochemistry 28: 5306-5310 (1989).

Feng L, Geck MK, Eliot AC, Kirsch JF. Aminotransferase activity and bioinformatic analysis of 1-aminocyclopropane-1-carboxylate synthase. Biochemistry 39: 15242-15249 (2000).

Ferrario-Mery S, Hodges M, Hirel B, Foyer CH. Photorespiration-dependent increases in phosphoenolpyruvate carboxylase, isocitrate dehydrogenase and glutamate dehydrogenase in transformed tobacco plants deficient in ferredoxin-dependent glutamine-alpha-ketoglutarate aminotransferase. Planta 214: 974 (2002).

Ferrario-Mery S, Hodges M, Hirel B, Foyer CH. Photorespiration-dependent increases in phosphoenolpyruvate carboxylase, isocitrate dehydrogenase and glutamate dehydrogenase in transformed tobacco plants deficient in ferredoxin-dependent glutamine-alpha-ketoglutarate aminotransferase. Planta 214: 877-886 (2002).

Ferrario-Mery S, Masclaux C, Suzuki A, Valadier MH, Hirel B, Foyer CH. Glutamine and alpha-ketoglutarate are metabolite signals involved in nitrate reductase gene transcription in untransformed and transformed tobacco plants deficient in ferredoxin-glutamine-alpha-ketoglutarate aminotransferase. Planta 213: 265-271 (2001).

Fieuw S, Muller-Rober B, Galvez S, Willmitzer L. Cloning and expression analysis of the cytosolic NADP(+)-dependent isocitrate dehydrogenase from potato. Implications for nitrogen metabolism. Plant Physiol. 107: 905-913 (1995).

Fiske MJ, Kane JF. Regulation of phenylalanine biosynthesis in Rhodotorula glutinis. J. Bacteriol. 160: 676-681 (1984).

Fiske MJ, Whitaker RJ, Jensen RA. Hidden overflow pathway to L-phenylalanine in Pseudomonas aeruginosa. J. Bacteriol. 154: 623-631 (1983).

Fitzgerald C, Swearengin TA, Yeargans G, McWhorter D, Cucchetti B, Seidler NW. Non-enzymatic glycosylation (or glycation) and inhibition of the pig heart cytosolic aspartate aminotransferase by glyceraldehyde 3-phosphate. J. Enzyme Inhib. 15: 79-89 (2000).

Forde BG, Lea PJ. Glutamate in plants: metabolism, regulation, and signalling. J. Exp. Bot. 58: 2339-2358 (2007).

Fotheringham IG, Grinter N, Pantaleone DP, Senkpeil RF, Taylor PP. Engineering of a novel biochemical pathway for the biosynthesis of L-2-aminobutyric acid in Escherichia coli K12. Bioorg. Med. Chem. 7: 2209-2213 (1999).

Fowler LJ, John RA. The reaction of ethanolamine O-sulphate with 4-aminobutyrate aminotransferase. Biochem. J. 197: 149-154 (1981).

Friedrich B, Magasanik B. Enzymes of agmatine degradation and the control of their synthesis in Klebsiella aerogenes. J. Bacteriol. 137: 1127-1133 (1979).

Fu MM, Silverman RB. Isolation and characterization of the product of inactivation of gamma-aminobutyric acid aminotransferase by gabaculine. Biorg. & Med. Chem. 7: 1581-1590 (1999).

Fuchs TM, Schneider B, Krumbach K, Eggeling L, Gross R. Characterization of a Bordetella pertussis diaminopimelate (DAP) biosynthesis locus identifies dapC, a novel gene coding for an N-succinyl-L,L-DAP aminotransferase. J. Bacteriol. 182: 3626-3631 (2000).

Fujii T, Mukaihara M, Agematu H, Tsunekawa H. Biotransformation of L-lysine to L-pipecolic acid catalyzed by L-lysine 6-aminotransferase and pyrroline-5-carboxylate reductase. Biosci. Biotechnol. Biochem. 66: 622-627 (2002).

Fujii T, Narita T, Agematu H, Agata N, Isshiki K. Characterization of L-lysine 6-aminotransferase and its structural gene from Flavobacterium lutescens IFO3084. J. Biochem. (Tokyo) 128: 391-397 (2000).

Funai T, Ichiyama A. Fidelity of translation initiation of mRNA for the precursor of rat mitochondrial serine:pyruvate/alanine:glyoxylate aminotransferase. J. Biochem. (Tokyo) 117: 1008-1016 (1995).

Funck D, Stadelhofer B, Koch W. Ornithine-delta-aminotransferase is essential for arginine catabolism but not for proline biosynthesis. BMC Plant Biol. 8: 40 (2008).

Fushiya S, Kanazawa T, Nozoe S. A novel class of potent gamma-aminobutyric acid aminotransferase inhibitor, 3-(hydroxyamino)propylamine and analogues. Bioorg. Med. Chem. 5: 2089-2094 (1997).

Gajewska E, Sklodowska M. Nickel-induced changes in nitrogen metabolism in wheat shoots. J. Plant Physiol. 166: 1034-1044 (2009).

Galas E, Florianowicz T. L-Glutamate-glyoxylate aminotransferase in Lactobacillus plantarum. Acta Microbiol. Pol. [B] 7: 243-252 (1975).

Garrido-Franco M, Ehlert S, Messerschmidt A, Marinkovic S, Huber R, Laber B, Bourenkov GP, Clausen T. Structure and function of threonine synthase from yeast. J. Biol. Chem. 277: 12396-12405 (2002).

Gebhardt JS, Wadsworth GJ, Matthews BF. Characterization of a single soybean cDNA encoding cytosolic and glyoxysomal isozymes of aspartate aminotransferase. Plant Mol. Biol. 37: 99-108 (1998).

Geck MK, Kirsch JF. A novel, definitive test for substrate channeling illustrated with the aspartate aminotransferase/malate dehydrogenase system. Biochemistry 38: 8032-8037 (1999).

Gibala MJ, Peirce N, Constantin-Teodosiu D, Greenhaff L. Exercise with low muscle glycogen augments TCA cycle anaplerosis but impairs oxidative energy provision in humans. J. Physiol. (London) 540: 1079-1086 (2002).

Gluck MR, Thomas RG, Davis KL, Haroutunian V. Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. Am. J. Psychiat. 159: 1165-1173 (2002).

Gong J, Hunter GA, Ferreira GC. Aspartate-279 in aminolevulinate synthase affects enzyme catalysis through enhancing the function of the pyridoxal 5'-phosphate cofactor. Biochemistry 37: 3509-3517 (1998).

Gossell-Williams M, Benjamin J. Choline: are our university students eating enough? West Indian Med. J. 55: 197-199 (2006).

Gough KC, Hawes WS, Kilpatrick J, Whitelam GC. Cyanobacterial GR6 glutamate-1-semialdehyde aminotransferase: a novel enzyme-based selectable marker for plant transformation. Plant Cell Rep. 20: 296-300 (2001).

Graber R, Kasper P, Malashkevich VN, Sandmeier E, Berger P, Gehring H, Jansonius JN, Christen P. Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme. Eur. J. Biochem. 232: 686-690 (1995).

Graber R, Kasper P, Malashkevich VN, Strop P, Gehring H, Jansonius JN, Christen P. Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation. J. Biol. Chem. 274: 31203-31208 (1999).

Gregerson RG, Miller SS, Petrowski M, Gantt JS, Vance CP. Genomic structure, expression and evolution of the alfalfa aspartate aminotransferase genes. Plant Mol. Biol. 25: 387-399 (1994).

Gregerson RG, Petrowski M, Larson RL, Gantt JS, Vance CP. Molecular analysis of allelic polymorphism at the AAT2 locus of alfalfa. Mol. Gen. Genet. 241: 124-128 (1993).

Grimm B. Primary structure of a key enzyme in plant tetrapyrrole synthesis: glutamate 1-semialdehyde aminotransferase. Proc. Natl. Acad. Sci. U.S.A. 87: 4169-4173 (1990).

Grimm B, Bull A, Welinder KG, Gough SP, Kannangara CG. Purification and partial amino acid sequence of the glutamate 1-semialdehyde aminotransferase of barley and Synechococcus. Carlsberg Res. Commun. 54: 67-79 (1989).

Grimm B, Smith AJ, Kannangara CG, Smith M. Gabaculine-resistant glutamate 1-semialdehyde aminotransferase of Synechococcus. Deletion of a tripeptide close to the NH2 terminus and internal amino acid substitution. J. Biol. Chem. 266: 12495-12501 (1991).

Gu R, Fonseca S, Puskas LG, Hackler L Jr, Zvara A, Dudits D, Pais MS. Transcript identification and profiling during salt stress and recovery of Populus euphratica. Tree Physiol. 24: 265-276 (2004).

Gupta M, Greven R, Jansen EEW, Jakobs C, Hogema BM, Froestl W, Snead OC, Bartels H, Grompe M, Gibson KM. Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria). J. Pharmacol. Exp. Ther. 302: 180-187 (2002).

Gutierrez A, Yoshimura T, Fuchikami Y, Soda K, Esaki N. A mutant D-amino acid aminotransferase with broad substrate specificity: construction by replacement of the interdomain loop Pro119-Arg120-Pro121 by Gly-Gly-Gly. Protein Eng. 11: 53-58 (1998).

Hagishita T, Yoshida T, Izumi Y, Mitsunaga T. Cloning and expression of the gene for serine-glyoxylate aminotransferase from an obligate methylotroph Hyphomicrobium methylovorum GM2. Eur. J. Biochem. 241: 1-5 (1996).

Han Q, Hanyong LY. Comparative characterization of Aedes 3-hydroxykynurenine transaminase/alanine glyoxylate transaminase and Drosophila serine pyruvate aminotransferase. FEBS Lett. 527: 199-204 (2002).

Han Q, Li J. Cysteine and keto acids modulate mosquito kynurenine aminotransferase catalyzed kynurenic acid production. FEBS Lett. 577: 381-385 (2004).

Han Q, Li J, Li J. pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I. Eur. J. Biochem. 271: 4804-4814 (2004).

Han Q, Robinson H, Gao YG, Vogelaar N, Wilson SR, Rizzi M, Li J. Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. J. Biol. Chem. 281: 37175-37182 (2006).

Hansson M, Gough SP, Kannangara CG, von Wettstein D. Chromosomal locations of six barley genes encoding enzymes of chlorophyll and heme biosynthesis and the sequence of the ferrochelatase gene identify two regulatory genes. Plant Physiol. Biochem. 36: 545-554 (1998).

Hansson M, Gough SP, Kannangara CG, vonWettstein D. Analysis of RNA and enzymes of potential importance for regulation of 5-aminolevulinic acid synthesis in the protochlorophyllide accumulating barley mutant tigrina-d(12). Plant Physiol. Biochem. 35: 827-836 (1997).

Hart CE, Race V, Achouri Y, Wiame E, Sharrard M, Olpin SE, Watkinson J, Bonham JR, Jaeken J, Matthijs G, Van Schaftingen E. Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway. Am. J. Hum. Genet. 80: 931-937 (2007).

Hartung W, Ratcliffe RG. Utilization of glycine and serine as nitrogen sources in the roots of Zea mays and Chamaegigas intrepidus. J. Exp. Bot. 53: 2305-2314 (2002).

Hasegawa T, Mihara M, Nakamuro K, Sayato Y. Mechanisms of selenium methylation and toxicity in mice treated with selenocystine. Arch. Toxicol. 71: 31-38 (1996).

Hassel B, Boldingh KA, Narvesen C, Iversen EG, Skrede KK. Glutamate transport, glutamine synthetase and phosphate-activated glutaminase in rat CNS white matter. A quantitative study. J. Neurochem. 87: 230-237 (2003).

Hausler RE, Bailey KJ, Lea PJ, Leegood RC. Control of photosynthesis in barley mutants with reduced activities of glutamine synthetase and glutamate synthase. 3. Aspects of glyoxylate metabolism and effects of glyoxylate on the activation state of ribulose-1,5-bisphosphate carboxylase/oxygenase. Planta 200: 388-396 (1996).

Havir EA. Inactivation of serine:glyoxylate and glutamate:glyoxylate aminotransferases from tobacco leaves by glyoxylate in the presence of ammonium ion. Plant Physiol. 80: 473-478 (1986).

Hayashi S, Noguchi T. Response to light of a specific aminotransferase for delta-aminolevulinate formation in higher plants. J. Biol. Chem. 258: 13693-13696 (1983).

Hearl WG, Churchich JE. Interactions between 4-aminobutyrate aminotransferase and succinic semialdehyde dehydrogenase, two mitochondrial enzymes. J. Biol. Chem. 259: 11459-11463 (1984).

Hedtke B, Alawady A, Chen S, Bornke F, Grimm B. HEMA RNAi silencing reveals a control mechanism of ALA biosynthesis on Mg chelatase and Fe chelatase. Plant Mol. Biol. 64: 733-742 (2007).

Heilbronn J, Wilson J, Berger BJ. Tyrosine aminotransferase catalyzes the final step of methionine recycling in Klebsiella pneumoniae. J. Bacteriol. 181: 1739-1747 (1999).

Hennig M, Grimm B, Contestabile R, John RA, Jansonius JN. Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity. Proc. Natl. Acad. Sci. U.S.A. 94: 4866-4871 (1997).

Herman CA, Im CS, Beale SI. Light-regulated expression of the gsa gene encoding the chlorophyll biosynthetic enzyme glutamate 1-semialdehyde aminotransferase in carotenoid-deficient Chlamydomonas reinhardtii cells. Plant Mol. Biol. 39: 289-297 (1999).

Herzfeld A, Mezl VA, Knox WE. Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues. Biochem. J. 166: 95-103 (1977).

Hester G, Stark W, Moser M, Kallen J, Markovic-Housley Z, Jansonius JN. Crystal structure of phosphoserine aminotransferase from Escherichia coli at 2.3 A resolution: comparison of the unligated enzyme and a complex with alpha-methyl-L-glutamate. J. Mol. Biol. 286: 829-850 (1999).

Higuchi K, Watanabe S, Takahashi M, Kawasaki S, Nakanishi H, Nishizawa NK, Mori S. Nicotianamine synthase gene expression differs in barleyand rice under Fe-deficient conditions. Plant J. 25: 159-167 (2001).

Ho CL, Noji M, Saito M, Yamazaki M, Saito K. Molecular characterization of plastidic phosphoserine aminotransferase in serine biosynthesis from Arabidopsis. Plant J. 16: 443-452 (1998).

Ho CL, Saito K. Molecular biology of the plastidic phosphorylated serine biosynthetic pathway in Arabidopsis thaliana. Amino Acids 20: 243-259 (2001).

Hodges M. Enzyme redundancy and the importance of 2-oxoglutarate in plant ammonium assimilation. J. Exp. Bot. 53: 905-916 (2002).

Hoedemaeker FJ, Davidson AR, Rose DR. A model for the nucleotide-binding domains of ABC transporters based on the large domain of aspartate aminotransferase. Proteins 30: 275-286 (1998).

Holbrook JD, Birdsey GM, Yang Z, Bruford MW, Danpure CJ. Molecular adaptation of alanine:glyoxylate aminotransferase targeting in primates. Mol. Biol. Evol. 17: 387-400 (2000).

Hopkins MH, Bichler KA, Su T, Chamberlain CL, Silverman RB. Inactivation of gamma-aminobutyric acid aminotransferase by various amine buffers. J. Enzyme Inhib. 6: 195-199 (1992).

Houghton JD, Brown SB, Gough SP, Kannangara CG. Biosynthesis of delta-aminolevulinate in Cyanidium caldarium: characterization of transfer RNA-glu, ligase, dehydrogenase and glutamate 1-semialdehyde aminotransferase. Carlsberg Res. Commun. 54: 131-143 (1989).

Hu CA, Bart Williams D, Zhaorigetu S, Khalil S, Wan G, Valle D. Functional genomics and SNP analysis of human genes encoding proline metabolic enzymes. Amino Acids 35: 655-664 (2008).

Hu H, You J, Fang Y, Zhu X, Qi Z, Xiong L. Characterization of transcription factor gene SNAC2 conferring cold and salt tolerance in rice. Plant Mol. Biol. 67: 169-181 (2008).

Huang H, Yu Y, Yi X, Zhang Y. Nitrogen metabolism of asparagine and glutamate in Vero cells studied by (1)H/ (15)N NMR spectroscopy. Appl. Microbiol. Biotechnol. 77: 427-436 (2007).

Hudson AO, Singh BK, Leustek T, Gilvarg C. An L,L-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants. Plant Physiol. 140: 292-301 (2006).

Huhn R, Stoermer H, Klingele B, Bausch E, Fois A, Farnetani M, Di Rocco M, Boue J, Kirk JM, Coleman R, Scherer G. Novel and recurrent tyrosine aminotransferase gene mutations in tyrosinemia type II. Hum. Genet. 102: 305-313 (1998).

Hukkanen A, Kokko H, Buchala A, Hayrinen J, Karenlampi S. Benzothiadiazole affects the leaf proteome in arctic bramble (Rubus arcticus). Mol. Plant Pathol. 9: 799-808 (2008).

Hutson SM, Berkich D, Drown P, Xu B, Aschner M, LaNoue KF. Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism. J. Neurochem. 71: 863-874 (1998).

Hutson SM, Bledsoe RK, Hall TR, Dawson PA. Cloning and expression of the mammalian cytosolic branched chain aminotransferase isoenzyme. J. Biol. Chem. 270: 30344-30352 (1995).

Igarashi D, Miwa T, Seki M, Kobayashi M, Kato T, Tabata S, Shinozaki K, Ohsumi C. Identification of photorespiratory glutamate:glyoxylate aminotransferase (GGAT) gene in Arabidopsis. Plant J. 33: 975-987 (2003).

Igarashi D, Tsuchida H, Miyao M, Ohsumi C. Glutamate:glyoxylate aminotransferase (GGAT) modulates amino acid contents during photorespiration. Plant Physiol. 142: 901-910 (2006).

Ikai H, Yamamoto S. Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii. J. Bacteriol. 179: 5118-5125 (1997).

Ikai H, Yamamoto S. Two genes involved in the 1,3-diaminopropane production pathway in Haemophilus influenzae. Biol. Pharm. Bull. 21: 170-173 (1998).

Im CS, Beale SI. Identification of possible signal transduction components mediating light induction of the Gsa gene for an early chlorophyll biosynthetic step in Chlamydomonas reinhardtii. Planta 210: 999-1005 (2000).

Im CS, Eberhard S, Huang K, Beck CF, Grossman AR. Phototropin involvement in the expression of genes encoding chlorophyll and carotenoid biosynthesis enzymes and LHC apoproteins in Chlamydomonas reinhardtii. Plant J. 48: 1-16 (2006).

Im CS, Matters GL, Beale SI. Calcium and calmodulin are involved in blue light induction of the gsa gene for an early chlorophyll biosynthetic step in Chlamydomonas. Plant Cell 8: 2245-2253 (1996).

Inokuchi R, Kuma KI, Miyata T, Okada M. Nitrogen-assimilating enzymes in land plants and algae: phylogenic and physiological perspectives. Physiol. Plant. 116: 1 (2002).

Inoue H, Takahashi M, Kobayashi T, Suzuki M, Nakanishi H, Mori S, Nishizawa NK. Identification and localisation of the rice nicotianamine aminotransferase gene OsNAAT1 expression suggests the site of phytosiderophore synthesis in rice. Plant Mol. Biol. 66: 193-203 (2008).

Inoue K, Kuramitsu S, Aki K, Watanabe Y, Takagi T, Nishigai M, Ikai A, Kagamiyama H. Branched-chain amino acid aminotransferase of Escherichia coli: overproduction and properties. J. Biochem. (Tokyo) 104: 777-784 (1988).

Inoue K, Kuramitsu S, Okamoto A, Hirotsu K, Higuchi T, Morino Y, Kagamiyama H. Tyr225 in aspartate aminotransferase: contribution of the hydrogen bond between Tyr225 and coenzyme to the catalytic reaction. J. Biochem. (Tokyo) 109: 570-576 (1991).

Iraqui I, Vissers S, Andre B, Urrestarazu A. Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae. Mol. Cell Biol. 19: 3360-3371 (1999).

Iraqui I, Vissers S, Cartiaux M, Urrestarazu A. Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily. Mol. Gen. Genet. 257: 238-248 (1998).

Ireland RJ, Joy KW. Purification and properties of an asparagine aminotransferase from Pisum sativum leaves. Arch. Biochem. Biophys. 223: 291-296 (1983).

Ishijima J, Nakai T, Kawaguchi S, Hirotsu K, Kuramitsu S. Free energy requirement for domain movement of an enzyme. J. Biol. Chem. 275: 18939-18945 (2000).

Ishikawa K, Kaneko E, Ichiyama A. Pyridoxal 5'-phosphate binding of a recombinant rat serine: pyruvate/alanine:glyoxylate aminotransferase. J. Biochem. (Tokyo) 119: 970-978 (1996).

Isupov MN, Antson AA, Dodson EJ, Dodson GG, Dementieva IS, Zakomirdina LN, Wilson KS, Dauter Z, Lebedev AA, Harutyunyan EH. Crystal structure of tryptophanase. J. Mol. Biol. 276: 603-623 (1998).

Ivic-Kardum M, Aurer A, Haban V, Aurer-Kozelj J, Szirovicza L. Aspartate aminotransferase--a marker of periodontal disease activity. Coll. Antropol. 23: 111-116 (1999).

Izumi Y, Yoshida T, Yamada H. Purification and characterization of serine-glyoxylate aminotransferase from a serine-producing methylotroph, Hyphomicrobium methylovorum GM2. Eur. J. Biochem. 190: 285-290 (1990).

Jacob C, Anwar A, Burkholz T. Perspective on recent developments on sulfur-containing agents and hydrogen sulfide signaling. Planta Med. 74: 1580-1592 (2008).

Jadaho SB, Yang RZ, Lin Q, Hu H, Anania FA, Shuldiner AR, Gong DW. Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver. Hepatology 39: 1297-1302 (2004).

Jeffery CJ, Barry T, Doonan S, Petsko GA, Ringe D. Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase. Protein Sci. 7: 1380-1387 (1998).

Jeffery CJ, M Gloss L, A Petsko G, Ringe D. The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase. Protein Eng. 13: 105-112 (2000).

Jhee KH, Yang LH, Ahmed SA, McPhie P, Rowlett R, Miles EW. Mutation of an active site residue of tryptophan synthase (beta-serine 377) alters cofactor chemistry. J. Biol. Chem. 273: 11417-11422 (1998).

Jhee KH, Yoshimura T, Miles EW, Takeda S, Miyahara I, Hirotsu K, Soda K, Kawata Y, Esaki N. Stereochemistry of the transamination reaction catalyzed by aminodeoxychorismate lyase from Escherichia coli: close relationship between fold type and stereochemistry. J. Biochem. (Tokyo) 128: 679-686 (2000).

John RA, Charteris A, Fowler LJ. The reaction of amino-oxyacetate with pyridoxal phosphate-dependent enzymes. Biochem. J. 171: 771-779 (1978).

Jones JM, Morrell JC, Gould SJ. Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases. J. Biol. Chem. 275: 12590-12597 (2000).

Jung MJ, Seiler N. Enzyme-activated irreversible inhibitors of L-ornithine:2-oxoacid aminotransferase. J. Biol. Chem. 253: 7431-7439 (1978).

Kafala B, Sasarman A. Isolation of the Staphylococcus aureus hemCDBL gene cluster coding for early steps in heme biosynthesis. Gene 199: 231-239 (1997).

Kanamori K, Ross BD, Kondrat RW. Rate of glutamate synthesis from leucine in rat brain measured in vivo by 15N NMR. J. Neurochem. 70: 1304-1315 (1998).

Kannangara CG, Gough SP. Biosynthesis of delta-aminolevulinate in greening barley leaves: glutamate 1-semialdehyde aminotransferase. Carlsberg Res. Commun. 43: 185-194 (1978).

Katagiri M, Nakamura M. Reappraisal of the 20th-century version of amino acid metabolism. Biochem. Biophys. Res. Commun. 312: 205-208 (2003).

Kato N, Dasgupta R, Smartt CT, Christensen BM. Glucosamine:fructose-6-phosphate aminotransferase: gene characterization, chitin biosynthesis and peritrophic matrix formation in Aedes aegypti. Insect Mol. Biol. 11: 207-216 (2002).

Kendziorek M, Paszkowski A. Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves. Acta Biochim. Biophys. Sin. (Shanghai) 40: 102-110 (2008).

Kenklies J, Ziehn R, Fritsche K, Pich A, Andreesen JR. Proline biosynthesis from L-ornithine in Clostridium sticklandii: purification of delta1-pyrroline-5-carboxylate reductase, and sequence and expression of the encoding gene, proC. Microbiology 145: 819-826 (1999).

Keys AJ. The re-assimilation of ammonia produced by photorespiration and the nitrogen economy of C(3) higher plants. Photosynth. Res. 87: 165-175 (2006).

Kikuchi H, Hirose S, Toki S, Akama K, Takaiwa F. Molecular characterization of a gene for alanine aminotransferase from rice (Oryza sativa). Plant Mol. Biol. 39: 149-159 (1999).

Kim DS, Churchich JE. Active site modification of 4-aminobutyrate aminotransferase with ATP analogs. Biochim. Biophys. Acta 916: 265-270 (1987).

Kim DS, Churchich JE. The reversible oxidation of vicinal SH groups in 4-aminobutyrate aminotransferase. Probes of conformational changes. J. Biol. Chem. 262: 14250-14254 (1987).

Kim DS, Moses U, Churchich JE. Gabaculine and m-carboxyphenyl-pyridoxamine 5-phosphate as probes of the catalytic binding sites of 4-aminobutyrate aminotransferase. Eur. J. Biochem. 118: 303-308 (1981).

Kim HR, Rho HW, Park JW, Park BH, Kim JS, Lee MW. Assay of ornithine aminotransferase with ninhydrin. Anal. Biochem. 223: 205-207 (1994).

Kim KJ, Park CJ, An JM, Ham BK, Lee BJ, Paek KH. CaAlaAT1 catalyzes the alanine: 2-oxoglutarate aminotransferase reaction during the resistance response against tobacco mosaic virus in hot pepper. Planta 221: 857-867 (2005).

Kim SJ, Jung YS, Kwon do Y, Kim YC. Alleviation of acute ethanol-induced liver injury and impaired metabolomics of S-containing substances by betaine supplementation. Biochem. Biophys. Res. Commun. 368: 893-898 (2008).

Kim YC, Jung YS, Kim SK. Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate. Food Chem. Toxicol. 43: 663-670 (2005).

Kim YT, Churchich JE. 4-Aminobutyrate aminotransferase: identification of lysine residues connected with catalytic activity. Biochim. Biophys. Acta 1077: 187-191 (1991).

Kim YT, Churchich JE. Sequence of the cysteinyl-containing peptides of 4-aminobutyrate aminotransferase. Identification of sulfhydryl residues involved in intersubunit linkage. Eur. J. Biochem. 181: 397-401 (1989).

Kim YT, Song YH, Churchich JE. Recombinant brain 4-aminobutyrate aminotransferases overexpression, purification, and identification of Lys-330 at the active site. Biochim. Biophys. Acta 1337: 248-256 (1997).

Kirk CA, Mett V, Reynolds PH. The aspartate aminotransferase-P1 gene from Lupinus angustifolius. Plant Physiol. 105: 763-764 (1994).

Ko TP, Wu SP, Yang WZ, Tsai H, Yuan HS. Crystallization and preliminary crystallographic analysis of the Escherichia coli tyrosine aminotransferase. Acta Crystallogr. D. Biol. Crystallogr. 55: 1474-1477 (1999).

Kobayashi K, Miyazawa S, Endo A. Isolation and inhibitory activity of gabaculine, a new potent inhibitor of gamma-aminobutyrate aminotransferase produced by a Streptomyces. FEBS Lett. 76: 207-210 (1977).

Kobayashi T, Nakayama Y, Itai RN, Nakanishi H, Yoshihara T, Mori S, Nishizawa NK. Identification of novel cis-acting elements, IDE1 and IDE2, of the barley IDS2 gene promoter conferring iron-deficiency-inducible, root-specific expression in heterogeneous tobacco plants. Plant J. 36: 780-793 (2003).

Koga J, Syono K, Ichikawa T, Adachi T. Involvement of L-tryptophan aminotransferase in indole-3-acetic acid biosynthesis in Enterobacter cloacae. Biochim. Biophys. Acta 1209: 241-247 (1994).

Kohler ES, Sankaranarayanan S, van Ginneken CJ, van Dijk P, Vermeulen JL, Ruijter JM, Lamers WH, Bruder E. The human neonatal small intestine has the potential for arginine synthesis; developmental changes in the expression of arginine-synthesizing and -catabolizing enzymes. BMC Dev. Biol. 8: 107 (2008).

Kondo K, Wakabayashi S, Kagamiyama H. Structural studies on aspartate aminotransferase from Escherichia coli. Covalent structure. J. Biol. Chem. 262: 8648-8657 (1987).

Kondo K, Wakabayashi S, Yagi T, Kagamiyama H. The complete amino acid sequence of aspartate aminotransferase from Escherichia coli: sequence comparison with pig isoenzymes. Biochem. Biophys. Res. Commun. 122: 62-67 (1984).

Kontani Y, Kawasaki S, Kaneko M, Matsuda K, Sakata SF, Tamaki N. Inhibitory effect of ethanol administration on beta-alanine-2-oxoglutarate aminotransferase (GABA aminotransferase) in disulfiram-pretreated rats. J. Nutr. Sci. Vitaminol. (Tokyo) 44: 165-176 (1998).

Kontani Y, Sakata SF, Matsuda K, Ohyama T, Sano K, Tamaki N. The mature size of rat 4-aminobutyrate aminotransferase is different in liver and brain. Eur. J. Biochem. 264: 218-222 (1999).

Koo YK, Nandi D, Silverman RB. The multiple active enzyme species of gamma-aminobutyric acid aminotransferase are not isozymes. Arch. Biochem. Biophys. 374: 248-254 (2000).

Kruse E, Grimm B, Beator J, Kloppstech K. Developmental and circadian control of the capacity for delta- aminolevulinic acid synthesis in green barley. Planta 202: 235-241 (1997).

Kugler P. Enzymes involved in glutamatergic and GABAergic neurotransmission. Int. Rev. Cytol. 147: 285-336 (1993).

Kumar N, Kumar S, Vats SK, Ahuja PS. Effect of altitude on the primary products of photosynthesis and the associated enzymes in barley and wheat. Photosynth. Res. 88: 63-71 (2006).

Kuramitsu S, Inoue K, Ogawa T, Ogawa H, Kagamiyama H. Aromatic amino acid aminotransferase of Escherichia coli: nucleotide sequence of the tyrB gene. Biochem. Biophys. Res. Commun. 133: 134-139 (1985).

Kuramitsu S, Ogawa T, Ogawa H, Kagamiyama H. Branched-chain amino acid aminotransferase of Escherichia coli: nucleotide sequence of the ilvE gene and the deduced amino acid sequence. J. Biochem. (Tokyo) 97: 993-999 (1985).

Kuramitsu S, Okuno S, Ogawa T, Ogawa H, Kagamiyama H. Aspartate aminotransferase of Escherichia coli: nucleotide sequence of the aspC gene. J. Biochem. (Tokyo) 97: 1259-1262 (1985).

Kwok EY, Hanson MR. GFP-labelled Rubisco and aspartate aminotransferase are present in plastid stromules and traffic between plastids. J. Exp. Bot. 55: 595-604 (2004).

Lain B, Yanez A, Iriarte A, Martinez-Carrion M. Aminotransferase variants as probes for the role of the N-terminal region of a mature protein in mitochondrial precursor import and processing. J. Biol. Chem. 273: 4406-4415 (1998).

Lain-Guelbenzu B, Cardenas J, Munoz-Blanco J. Purification and properties of L-alanine aminotransferase from Chlamydomonas reinhardtii. Eur. J. Biochem. 202: 881-887 (1991).

Lam HM, Coschigano KT, Oliveira IC, Melo-Oliveira R, Coruzzi GM. The molecular-genetics of nitrogen assimilation into amino acids in higher plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 47: 569-593 (1996).

Lancien M, Martin M, Hsieh MH, Leustek T, Goodman H, Coruzzi GM. Arabidopsis glt1-T mutant defines a role for NADH-GOGAT in the non-photorespiratory ammonium assimilatory pathway. Plant J. 29: 347-358 (2002).

Large PJ. Enzymes and pathways of polyamine breakdown in microorganisms. FEMS Microbiol. Rev. 88: 249-262 (1992).

Lawton JM, Doonan S. Thermal inactivation and chaperonin-mediated renaturation of mitochondrial aspartate aminotransferase. Biochem. J. 334: 219-224 (1998).

Le Roux MR, Khan S, Valentine AJ. Organic acid accumulation may inhibit N2 fixation in phosphorus-stressed lupin nodules. New Phytol. 177: 956-964 (2008).

Ledwidge R, Blanchard JS. The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis. Biochemistry 38: 3019-3024 (1999).

Lee IS, Muragaki Y, Ideguchi T, Hase T, Tsuji M, Ooshima A, Okuno E, Kido R. Molecular cloning and sequencing of a cDNA encoding alanine-glyoxylate aminotransferase 2 from rat kidney. J. Biochem. (Tokyo) 117: 856-862 (1995).

Lee IS, Takio K, Kido R, Titani K. Purification and amino- and carboxyl-terminal amino acid sequences of alanine-glyoxylate transaminase 1 from human liver. J. Biochem. (Tokyo) 116: 12-17 (1994).

Lee J, Sperandio V, Frantz DE, Longgood J, Camilli A, Phillips MA, Michael AJ. An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae. J. Biol. Chem. 284: 9899-9907 (2009).

Lee SG, Choi TJ, Kim YT. High level expression and purification of recombinant 4-aminobutyrate aminotransferases in Escherichia coli. J. Microbiol. Biotechnol. 6: 162-166 (1996).

Leegood RC, Lea PJ, Adcock MD, Hausler RE. The regulation and control of photorespiration. J. Exp. Bot. 46: 1397-1414 (1995).

Levillain O, Hus-Citharel A, Garvi S, Peyrol S, Reymond I, Mutin M, Morel F. Ornithine metabolism in male and female rat kidney: mitochondrial expression of ornithine aminotransferase and arginase II. Am. J. Physiol. Renal Physiol. 286: F727-F738 (2004).

Liang X, Abel S, Keller JA, Shen NF, Theologis A. The 1-aminocyclopropane-1-carboxylate synthase gene family of Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A. 89: 11046-11050 (1992).

Liang Z, Yu C, Huang AH. Conversion of glycerate to serine in intact spinach leaf peroxisomes. Arch. Biochem. Biophys. 233: 393-401 (1984).

Lieber CS. New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments. Curr. Gastroenterol. Rep. 6: 60-65 (2004).

Liepman AH, Olsen LI. Genomic analysis of aminotransferases in Arabidopsis thaliana. Crit. Rev. Plant Sci. 23: 73-89 (2004).

Liepman AH, Olsen LJ. Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis. Plant Physiol. 131: 215-227 (2003).

Liepman AH, Olsen LJ. Peroxisomal alanine:glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana. Plant J. 25: 487-498 (2001).

Limami AM, Glevarec G, Ricoult C, Cliquet JB, Planchet E. Concerted modulation of alanine and glutamate metabolism in young Medicago truncatula seedlings under hypoxic stress. J. Exp. Bot. 59: 2325-2335 (2008).

Lin CC, Kao CH. Regulation of ammonium-induced proline accumulation in detached rice leaves. Plant Growth Regul. 35: 69-74 (2001).

Ling M, Allen SW, Wood JM. Sequence analysis identifies the proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase domains of the multifunctional Escherichia coli PutA protein. J. Mol. Biol. 243: 950-956 (1994).

Lodato RF, Smith RJ, Valle D, Phang JM, Aoki TT. Regulation of proline biosynthesis: the inhibition of pyrroline-5-carboxylate synthase activity by ornithine. Metabolism 30: 908-913 (1981).

Lopukhina A, Dettenberg M, Weiler EW, Hollander-Czytko H. Cloning and characterization of a coronatine-regulated tyrosine aminotransferase from Arabidopsis. Plant Physiol. 126: 1678-1687 (2001).

Lorente S, Montoro MA. Cholestasis of pregnancy. Gastroenterol. Hepatol. 30: 541-547 (2007).

Loscher W. Effect of inhibitors of GABA aminotransferase on the metabolism of GABA in brain tissue and synaptosomal fractions. J. Neurochem. 36: 1521-1527 (1981).

Loscher W, Honack D, Gramer M. Use of inhibitors of gamma-aminobutyric acid (GABA) transaminase for the estimation of GABA turnover in various brain regions of rats: a reevaluation of aminooxyacetic acid. J. Neurochem. 53: 1737-1750 (1989).

Lumb MJ, Drake AF, Danpure CJ. Effect of N-terminal alpha-helix formation on the dimerization and intracellular targeting of alanine:glyoxylate aminotransferase. J. Biol. Chem. 274: 20587-20596 (1999).

Lumb MJ, Purdue PE, Danpure CJ. Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular targeting. Analysis of the feline gene. Eur. J. Biochem. 221: 53-62 (1994).

Luong TN, Kirsch JF. A continuous coupled spectrophotometric assay for tyrosine aminotransferase activity with aromatic and other nonpolar amino acids. Anal. Biochem. 253: 46-49 (1997).

Maaheimo H, Fiaux J, Cakar ZP, Bailey JE, Sauer U, Szyperski T. Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional C-13 labeling of common amino acids. Eur. J. Biochem. 268: 2464-2479 (2001).

Mahon MM, Graber R, Christen P, Malthouse JP. The aspartate aminotransferase-catalysed exchange of the alpha-protons of aspartate and glutamate: the effects of the R386A and R292V mutations on this exchange reaction. Biochim. Biophys. Acta 1434: 191-201 (1999).

Malashkevich VN, Jager J, Ziak M, Sauder U, Gehring H, Christen P, Jansonius JN. Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry 34: 405-414 (1995).

Malatrasi M, Corradi M, Svensson JT, Close TJ, Gulli M, Marmiroli N. A branched-chain amino acid aminotransferase gene isolated from Hordeum vulgare is differentially regulated by drought stress. Theor. Appl. Genet. 113: 965-976 (2006).

Malthankar-Phatak GH, de Lanerolle N, Eid T, Spencer DD, Behar KL, Spencer SS, Kim JH, Lai JC. Differential glutamate dehydrogenase (GDH) activity profile in patients with temporal lobe epilepsy. Epilepsia 47: 1292-1299 (2006).

Manoharan K, Chae HS, Cha JM, Cho SH, Shin SH, Cho BH, Lee WS. Synthesis of phosphatidylserine in carrot cells cultured under carbon-source starvation. Plant Cell Physiol. 41: 1143-1148 (2000).

Marchenko GN, Marchenko ND, Tsygankov YD, Chistoserdov AY. Organization of threonine biosynthesis genes from the obligate methylotroph Methylobacillus flagellatus. Microbiology 145: 3273-3282 (1999).

Markova M, Peneff C, Hewlins MJ, Schirmer T, John RA. Determinants of substrate specificity in omega-aminotransferases. J. Biol. Chem. 280: 36409-36416 (2005).

Martin M, de la Banda IG, Sabater B. L-Alanine: 2-ketoglutarate aminotransferase from maize embryo with complex kinetic properties for L-alanine. Rev. Esp. Fisiol. 32: 131-136 (1976).

Martínez-Chantar ML, Vazquez-Chantada M, Ariz U, Martínez N, Varela M, Luka Z, Capdevila A, Rodríguez J, Aransay AM, Matthiesen R, Yang H, Calvisi DF, Esteller M, Fraga M, Lu SC, Wagner C, Mato JM. Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice. Hepatology 47: 1191-1199 (2008).

Matsuzawa T. Disease of the ornithine-proline pathway: delta 1-pyrroline-5-carboxylate reductase deficiency in the retina of retinal degeneration mice. Metab. Pediatr. Syst. Ophthalmol. 6: 123-128 (1982).

Matsuzawa T, Ishiguro I. Delta 1-pyrroline-5-carboxylate reductase from baker's yeast: further purification by affinity chromatography with 5' AMP-Sepharose 4B. Biochim. Biophys. Acta 616: 381-383 (1980).

Maul DM, Schuster SM. A comparison of the cytosolic and mitochondrial forms of asparagine/glyoxylate aminotransferase. Arch. Biochem. Biophys. 251: 577-584 (1986).

Mayer SM, Gawlita E, Avissar YJ, Anderson VE, Beale SI. Intermolecular nitrogen transfer in the enzymic conversion of glutamate to d-aminolevulinic acid by extracts of Chlorella vulgaris. Plant Physiol. 101: 1029-1038 (1993).

McCoy AJ, Adams NE, Hudson AO, Gilvarg C, Leustek T, Maurelli AT. L,L-Diaminopimelate aminotransferase, a trans-kingdom enzyme shared by Chlamydia and plants for synthesis of diaminopimelate/lysine. Proc. Natl. Acad. Sci. U.S.A. 103: 17909-17914 (2006).

Medina-Kauwe LK, Tobin AJ, Meirleir LD, Jaeken J, Jakobs C, Nyhan WL, Gibson KM. 4-Aminobutyrate aminotransferase (GABA-transaminase) deficiency. J. Inherit. Metab. Dis. 22: 414-427 (1999).

Mehta PK, Christen P. Homology of 1-aminocyclopropane-1-carboxylate synthase, 8-amino-7-oxononanoate synthase, 2-amino-6-caprolactam racemase, 2,2-dialkylglycine decarboxylase, glutamate-1-semialdehyde 2,1-aminomutase ... with aminotransferases. Biochem. Biophys. Res. Commun. 198: 138-143 (1994).

Mehta PK, Christen P. The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes. Adv. Enzymol. Relat. Areas Mol. Biol. 74: 129-184 (2000).

Mehta PK, Hale TI, Christen P. Aminotransferases: demonstration of homology and division into evolutionary subgroups. Eur. J. Biochem. 214: 549-561 (1993).

Mehta PK, Hale TI, Christen P. Evolutionary relationships among aminotransferases. Tyrosine aminotransferase, histidinol-phosphate aminotransferase, and aspartate aminotransferase are homologous proteins. Eur. J. Biochem. 186: 249-253 (1989).

Meister M, Agostino A, Hatch MD. The roles of malate and aspartate in C4 photosynthetic metabolism of Flaveria bidentis (L). Planta 199: 262-269 (1996).

Melcher K, Rose M, Kunzler M, Braus GH, Entian KD. Molecular analysis of the yeast SER1 gene encoding 3-phosphoserine aminotransferase: regulation by general control and serine repression. Curr. Genet. 27: 501-508 (1995).

Metcalf WW, Zhang JK, Shi X, Wolfe RS. Molecular, genetic, and biochemical characterization of the serC gene of Methanosarcina barkeri Fusaro. J. Bacteriol. 178: 5797-5802 (1996).

Meton I, Egea M, Fernandez F, Eraso MC, Baanante IV. The N-terminal sequence directs import of mitochondrial alanine aminotransferase into mitochondria. FEBS Lett. 566: 251-254 (2004).

Mett V, Mett VL, Reynolds PH. The aspartate aminotransferase-P2 gene from Lupinus angustifolius. Plant Physiol. 106: 1683-1684 (1994).

Miesak BH, Coruzzi GM. Molecular and physiological analysis of Arabidopsis mutants defective in cytosolic or chloroplastic aspartate aminotransferase. Plant Physiol. 129: 650-660 (2002).

Miflin BJ, Lea PJ. The pathway of nitrogen assimilation in plants. Phytochemistry 15: 873-885 (1976).

Mikosch CA, Denger K, Schafer EM, Cook AM. Anaerobic oxidations of cysteate: degradation via L-cysteate:2-oxoglutarate aminotransferase in Paracoccus pantotrophus. Microbiology 145: 1153-1160 (1999).

Minatogawa Y, Tone S, Allsop J, Purdue PE, Takada Y, Danpur CJ, Kido R. A serine-to-phenylalanine substitution leads to loss of alanine:glyoxylate aminotransferase catalytic activity and immunoreactivity in a patient with primary hyperoxaluria type 1. Hum. Mol. Genet. 1: 643-644 (1992).

Miyashita Y, Dolferus R, Ismond KP, Good AG. Alanine aminotransferase catalyses the breakdown of alanine after hypoxia in Arabidopsis thaliana. Plant J. 49: 1108-1121 (2007).

Mo X, Zhu Q, Li X, Li J, Zeng Q, Rong H, Zhang H, Wu P. The hpa1 mutant of Arabidopsis reveals a crucial role of histidine homeostasis in root meristem maintenance. Plant Physiol. 141: 1425-1435 (2006).

Mohamed SA, Mohamed TM, Fahmy AS, El-Badry MO, Abdel-Gany SS. Fasciola gigantica: enzymes of the ornithine-proline-glutamate pathway - characterization of delta1-pyrroline-5-carboxylate dehydrogenase. Exp. Parasitol. 118: 47-53 (2008).

Mohanty S, Grimm B, Tripathy BC. Light and dark modulation of chlorophyll biosynthetic genes in response to temperature. Planta 224: 692-699 (2006).

Monschau N, Stahmann KP, Sahm H, McNeil JB, Bognar AL. Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis. FEMS Microbiol. Lett. 150: 55-60 (1997).

Moran J, Alavez S, Rivera-Gaxiola M, Valencia A, Hurtado S. Effect of NMDA antagonists on the activity of glutaminase and aspartate aminotransferase in the developing rat cerebellum. Int. J. Dev. Neurosci. 17: 57-65 (1999).

Morgunov I, Srere PA. Interaction between citrate synthase and malate dehydrogenase. Substrate channeling of oxaloacetate. J. Biol. Chem. 273: 29540-29544 (1998).

Mori S. Iron acquisition by plants. Curr. Opin. Plant Biol. 2: 250-253 (1999).

Moses U, Churchich JE. Reactivity of one thiol group in the dimeric protein, 4-aminobutyrate aminotransferase. Biochim. Biophys. Acta 613: 392-400 (1980).

Motley A, Lumb MJ, Oatey PB, Jennings PR, De Zoysa PA, Wanders RJ, Tabak HF, Danpure CJ. Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. J. Cell Biol. 131: 95-109 (1995).

Mouratou B, Kasper P, Gehring H, Christen P. Conversion of tyrosine phenol-lyase to dicarboxylic amino acid beta-lyase, an enzyme not found in nature. J. Biol. Chem. 274: 1320-1325 (1999).

Muench DG, Archibold OW, Good AG. Hypoxic metabolism in wild rice (Zizania-palustris): enzyme-induction and metabolite production. Physiol. Plant. 89: 165-171 (1993).

Muench DG, Good AG. Hypoxically inducible barley alanine aminotransferase: cDNA cloning and expression analysis. Plant Mol. Biol. 24: 417-427 (1994).

Mukorah F, Razunguzwa B, Masola B. Stabilization of rat liver mitochondrial alanine aminotransferase with ethanol and trehalose. Cryobiology 37: 300-308 (1998).

Muller U, van Assema F, Gunsior M, Orf S, Kremer S, Schipper D, Wagemans A, Townsend CA, Sonke T, Bovenberg R, Wubbolts M. Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg). Metab. Eng. 8: 196-208 (2006).

Muscolo A, Panuccio MR, Sidari M, Sessi E, Nardi S. Alteration of amino acid metabolism by humic substances during germination of Pinus laricio seeds. Seed Sci. Technol. 30: 205-210 (2002).

Nair SP, Harwood JL, John RA. Direct identification and quantification of the cofactor in glutamate semialdehyde aminotransferase from pea leaves. FEBS Lett. 283: 4-6 (1991).

Nakabachi A, Ishikawa H. Differential display of mRNAs related to amino acid metabolism in the endosymbiotic system of aphids. Insect Biochem. Mol. Biol. 27: 1057-1062 (1997).

Nakai T, Okada K, Akutsu S, Miyahara I, Kawaguchi S, Kato R, Kuramitsu S, Hirotsu K. Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate. Biochemistry 38: 2413-2424 (1999).

Nakai T, Okada K, Kawaguchi Si, Kato R, Kuramitsu S, Hirotsu K. Crystallization and preliminary X-ray characterization of aspartate aminotransferase from an extreme thermophile, Thermus thermophilus HB8. Acta Crystallogr. D. Biol. Crystallogr. 54: 1032-1034 (1998).

Nakamura Y, Tolbert NE. Serine: glyoxylate, alanine:glyoxylate, and glutamate:glyoxylate aminotransferase reactions in peroxisomes from spinach leaves. J. Biol. Chem. 258: 7631-7638 (1983).

Nanda K. Non-alcoholic steatohepatitis in children. Pediatr. Transplant. 8: 613-618 (2004).

Neuffer B, Hurka H. Colonization history and introduction dynamics of Capsella bursa-pastoris (Brassicaceae) in North America: isozymes and quantitative traits. Mol. Ecol. 8: 1667-1681 (1999).

Newsholme P, Brennan L, Bender K. Amino acid metabolism, {beta}-cell function, and diabetes. Diabetes 55 Suppl. 2: S39-S47 (2006).

Nierop Groot MN, de Bont JAM. Conversion of phenylalanine to benzaldehyde initiated by an aminotransferase in Lactobacillus plantarum. Appl. Environ. Microbiol. 64: 3009-3013 (1998).

Niessen M, Thiruveedhi K, Rosenkranz R, Kebeish R, Hirsch HJ, Kreuzaler F, Peterhansel C. Mitochondrial glycolate oxidation contributes to photorespiration in higher plants. J. Exp. Bot. 58: 2709-2715 (2007).

Nishiyama K, Berstein G, Oda T, Ichiyama A. Cloning and nucleotide sequence of cDNA encoding human liver serine-pyruvate aminotransferase. Eur. J. Biochem. 194: 9-18 (1990).

Nishiyama K, Funai T, Katafuchi R, Hattori F, Onoyama K, Ichiyama A. Primary hyperoxaluria type I due to a point mutation of T to C in the coding region of the serine:pyruvate aminotransferase gene. Biochem. Biophys. Res. Commun. 176: 1093-1099 (1991).

Nogaj LA, Srivastava A, van Lis R, Beale SI. Cellular levels of glutamyl-tRNA reductase and glutamate-1-semialdehyde aminotransferase do not control chlorophyll synthesis in Chlamydomonas reinhardtii. Plant Physiol. 139: 389-396 (2005).

Noguchi T, Fujiwara S. Development of glutamate:glyoxylate aminotransferase in the cotyledons of cucumber (Cucumis sativus) seedlings. Biochem. J. 201: 209-214 (1982).

Noguchi T, Fujiwara S. Identification of mammalian aminotransferases utilizing glyoxylate or pyruvate as amino acceptor. Peroxisomal and mitochondrial asparagine aminotransferase. J. Biol. Chem. 263: 182-186 (1988).

Noguchi T, Hayashi S. Plant leaf alanine: 2-oxoglutarate aminotransferase. Peroxisomal localization and identity with glutamate:glyoxylate aminotransferase. Biochem. J. 195: 235-239 (1981).

Noguchi T, Hayashi S. Peroxisomal localization and properties of tryptophan aminotransferase in plant leaves. J. Biol. Chem. 255: 2267-2269 (1980).

Nomura M, Mai HT, Fujii M, Hata S, Izui K, Tajima S. Phosphoenolpyruvate carboxylase plays a crucial role in limiting nitrogen fixation in Lotus japonicus nodules. Plant Cell Physiol. 47: 613-621 (2006).

O'Gaora P, Maskel D, Coleman D, Cafferkey M, Dougan G. Cloning and characterisation of the serC and aroA genes of Yersinia enterocolitica, and construction of an aroA mutant. Gene 84: 23-30 (1989).

O'Quinn PR, Knabe DA, Wu G. Arginine catabolism in lactating porcine mammary tissue. J. Anim. Sci. 80: 467-474 (2002).

Obungu VH, Kiaira JK, Njogu RM, Olembo NK. Catabolism of proline by procyclic culture forms of Trypanosoma congolense. Comp. Biochem. Physiol. [B] 123: 59-65 (1999).

Oda T, Funai T, Ichiyama A. Generation from a single gene of two mRNAs that encode the mitochondrial and peroxisomal serine:pyruvate aminotransferase of rat liver. J. Biol. Chem. 265: 7513-7519 (1990).

Oda T, Kitamura N, Nakanishi S, Ichiyama A. Cloning and expression in Escherichia coli of cDNA for serine:pyruvate aminotransferase of rat liver. Eur. J. Biochem. 150: 415-421 (1985).

Oda T, Miyajima H, Suzuki Y, Ichiyama A. Nucleotide sequence of the cDNA encoding the precursor for mitochondrial serine:pyruvate aminotransferase of rat liver. Eur. J. Biochem. 168: 537-542 (1987).

Oda T, Nishiyama K, Ichiyama A. Characterization and sequence analysis of rat serine:pyruvate/alanine:glyoxylate aminotransferase gene. Genomics 17: 59-65 (1993).

Oda T, Uchida C, Miura S. Mitochondrial targeting signal-induced conformational change and repression of the peroxisomal targeting signal of the precursor for rat liver serine:pyruvate/alanine:glyoxylate aminotransferase. J. Biochem. (Tokyo) 127: 665-671 (2000).

Ogawa T, Fukuda M, Sasaoka K. Occurrence of D-amino acid aminotransferase in pea seedlings. Biochem. Biophys. Res. Commun. 52: 998-1002 (1973).

Ohyama T, Matsuda K, Tachibana H, Fujimoto Sakata S, Mori M, Horiuchi M, Tamaki N. Purification and expression of a processing protease on beta-alanine-oxoglutarate aminotransferase from rat liver mitochondria. FEBS Lett. 572: 251-255 (2004).

Okamoto A, Ishii S, Hirotsu K, Kagamiyama H. The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity. Biochemistry 38: 1176-1184 (1999).

Okamoto A, Nakai Y, Hayashi H, Hirotsu K, Kagamiyama H. Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network. J. Mol. Biol. 280: 443-461 (1998).

Okamoto T, Maruyama A, Imura S, Takeyama H, Naganuma T. Comparative phylogenetic analyses of Halomonas variabilis and related organisms based on 16S rRNA, gyrB and ectBC gene sequences. Syst. Appl. Microbiol. 27: 323-333 (2004).

Okuno E, Minatogawa Y, Nakamura M, Kamoda N, Nakanishi J, Makino M, Kido R. Crystallization and characterization of human liver kynurenine:glyoxylate aminotransferase. Identity with alanine:glyoxylate aminotransferase and serine:pyruvate aminotransferase. Biochem. J. 189: 581-590 (1980).

Ono H, Sawada K, Khunajakr N, Tao T, Yamamoto M, Hiramoto M, Shinmyo A, Takano M, Murooka Y. Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata. J. Bacteriol. 181: 91-99 (1999).

Orzechowski S, Socha-Hanc J, Paszkowski A. Alanine aminotransferase and glycine aminotransferase from maize (Zea mays L.) leaves. Acta Biochim. Pol. 46: 447-457 (1999).

Osei YD, Churchich JE. Screening and sequence determination of a cDNA encoding the human brain 4-aminobutyrate aminotransferase. Gene 155: 185-187 (1995).

Oue S, Okamoto A, Yano T, Kagamiyama H. Cocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: structural comparison with the enzyme-C4-dicarboxylic analog complex. J. Biochem. (Tokyo) 127: 337-343 (2000).

Ovadi J, Srere PA. Macromolecular compartmentation and channeling. Int. Rev. Cytol. 192: 255-280 (2000).

Palmieri G, Di Palo M, Scaloni A, Orru S, Marino G, Sannia G. Glutamate-1-semialdehyde aminotransferase from Sulfolobus solfataricus. Biochem. J. 320: 541-545 (1996).

Pandey R, Agarwal RM, Jeevaratnam K, Sharma GL. Osmotic stress-induced alterations in rice (Oryza sativa L.) and recovery on stress release. Plant Growth Regul. 42: 79-87 (2004).

Park J, Osei YD, Churchich JE. Isolation and characterization of recombinant mitochondrial 4-aminobutyrate aminotransferase. J. Biol. Chem. 268: 7636-7699 (1993).

Park LC, Gibson GE, Bunik V, Cooper AJ. Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine. Biochem. Pharmacol. 58: 1557-1565 (1999).

Pascarella S, Schirch V, Bossa F. Similarity between serine hydroxymethyltransferase and other pyridoxal phosphate-dependent enzymes. FEBS Lett. 331: 145-149 (1993).

Pascarella S, Schirch V, Bossa F. Similarity between serine hydroxymethyltransferase and other pyridoxal phosphate-dependent enzymes. FEBS Lett. 331: 145-149 (1993).

Paszkowski A. Some properties of serine: glyoxylate aminotransferase from rye seedlings (Secale cereale L.). Acta Biochim. Pol. 38: 437-448 (1991).

Paszkowski A, Niedzielska A. Serine:glyoxylate aminotransferase from the seedlings of rye (Secale cereale L.). Acta Biochim. Pol. 37: 277-282 (1990).

Paszkowski A, Niedzielska A. Glutamate:glyoxylate aminotransferase from the seedlings of rye (Secale cereale L.). Acta Biochim. Pol. 36: 17-29 (1989).

Pawlowski K, Gough SP, Kannangara CG, Debruijn FJ. Characterization of a 5-aminolevulinic acid synthase mutant of Azorhizobium caulinodans ORS571. Mol. Plant Microbe Interact. 6: 35-44 (1993).

Persson J, Gardestrom P, Nasholm T. Uptake, metabolism and distribution of organic and inorganic nitrogen sources by Pinus sylvestris. J. Exp. Bot. 57: 2651-2659 (2006).

Perysinakis A, Kinghorn JR, Drainas C. Glutamine synthetase/glutamate synthase ammonium-assimilating pathway in Schizosaccharomyces pombe. Curr. Microbiol. 30: 367-372 (1995).

Petersen S, Mack C, De Graaf AA, Riedel C, Eikmanns BJ, Sahm H. Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo. Metab. Eng. 3: 344-361 (2001).

Pineda T, Churchich JE. Unfolding of 4-aminobutyrate aminotransferase equilibrium and kinetic studies. Biochim. Biophys. Acta 1207: 173-178 (1994).

Plant N, Kitchen I, Goldfarb PS, Gibson GG. Developmental modulation of cysteine conjugate beta-lyase/glutamine transaminase K/kynurenine aminotransferase mRNA in rat brain. Eur. J. Drug Metab. Pharmacokinet. 22: 335-339 (1997).

Polakof S, Ceinos RM, Fernandez-Duran B, Miguez JM, Soengas JL. Daily changes in parameters of energy metabolism in brain of rainbow trout: dependence on feeding. Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 146: 265-273 (2007).

Powell JT, Morrison JF. Enzyme-enzyme interaction and the biosynthesis of aromatic amino acids in Escherichia coli. Biochim. Biophys. Acta 568: 467-474 (1979).

Powell JT, Morrison JF. The purification and properties of the aspartate aminotransferase and aromatic-amino-acid aminotransferase from Escherichia coli. Eur. J. Biochem. 87: 391-400 (1978).

Prell J, Boesten B, Poole P, Priefer UB. The Rhizobium leguminosarum bv. viciae VF39 gamma-aminobutyrate (GABA) aminotransferase gene (gabT) is induced by GABA and highly expressed in bacteroids. Microbiology 148: 615-623 (2002).

Purdue PE, Lumb MJ, Danpure CJ. Molecular evolution of alanine/glyoxylate aminotransferase 1 intracellular targeting. Analysis of the marmoset and rabbit genes. Eur. J. Biochem. 207: 757-766 (1992).

Purdue PE, Lumb MJ, Fox M, Griffo G, Hamon-Benais C, Povey S, Danpure CJ. Characterization and chromosomal mapping of a genomic clone encoding human alanine:glyoxylate aminotransferase. Genomics 10: 34-42 (1991).

Purdue PE, Takada Y, Danpure CJ. Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1. J. Cell Biol. 111: 2341-2351 (1990).

Qu K, Martin DL, Lawrence CE. Motifs and structural fold of the cofactor binding site of human glutamate decarboxylase. Protein Sci. 7: 1092-1105 (1998).

Qu le Q, Takaiwa F. Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice. Plant Biotechnol. J. 2: 113-125 (2004).

Quintero MJ, Muro-Pastor AM, Herrero A, Flores E. Arginine catabolism in the cyanobacterium Synechocystis sp. strain PCC 6803 involves the urea cycle and arginase pathway. J. Bacteriol. 182: 1008-1015 (2000).

Ramos F, el Guezzar M, Grenson M, Wiame JM. Mutations affecting the enzymes involved in the utilization of 4-aminobutyric acid as nitrogen source by the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 149: 401-404 (1985).

Reed RE, Hess JL. Partial purification and characterization of aspartate aminotransferases from seedling oat leaves. J. Biol. Chem. 250: 4456-4461 (1975).

Rees TA. Mitochondrial oxidative phosphorylation is required for ammonium assimilation in light in a marine diatom. Physiol. Plant. 117: 558-563 (2003).

Rehfeld DW, Tolbert NE. Aminotransferases in peroxisomes from spinach leaves. J. Biol. Chem. 247: 4803-4811 (1972).

Rejdak R, Zielinska E, Shenk Y, Turski WA, Okuno E, Zarnowski T, Zagorski Z, Zrenner E, Kohler K. Ontogenic changes of kynurenine aminotransferase I activity and its expression in the chicken retina. Vision Res. 43: 1513-1517 (2003).

Reumann S, Weber AP. Plant peroxisomes respire in the light: some gaps of the photorespiratory C2 cycle have become filled - others remain. Biochim. Biophys. Acta 1763: 1496-1510 (2006).

Ricoult C, Cliquet JB, Limami AM. Stimulation of alanine amino transferase (AlaAT) gene expression and alanine accumulation in embryo axis of the model legume Medicago truncatula contribute to anoxia stress tolerance. Physiol. Plant. 123: 30-39 (2005).

Ricoult C, Echeverria LO, Cliquet JB, Limami AM. Characterization of alanine aminotransferase (AlaAT) multigene family and hypoxic response in young seedlings of the model legume Medicago truncatula. J. Exp. Bot. 57: 3079-3089 (2006).

Rishavy MA, Cleland WW. 13C and 15N kinetic isotope effects on the reaction of aspartate aminotransferase and the tyrosine-225 to phenylalanine mutant. Biochemistry 39: 7546-7551 (2000).

Rivero RM, Ruiz JM, Romero LM. Importance of N source on heat stress tolerance due to the accumulation of proline and quaternary ammonium compounds in tomato plants. Plant Biol. (Stuttg.) 6: 702-707 (2004).

Ro HS. Effects of salts on the conformation and catalytic properties of D-amino acid aminotransferase. J. Biochem. Mol. Biol. 35: 306-312 (2002).

Roosens NH, Al Bitar F, Loenders K, Angenon G, Jacobs M. Overexpression of ornithine-delta-aminotransferase increases proline biosynthesis and confers osmotolerance in transgenic plants. Mol. Breed. 9: 73-80 (2002).

Roosens NH, Thu TT, Iskandar HM, Jacobs M. Isolation of the ornithine-delta-aminotransferase cDNA and effect of salt stress on its expression in Arabidopsis thaliana. Plant Physiol. 117: 263-271 (1998).

Rosenthal GA, Dahlman DL. Interaction of L-canaline with ornithine aminotransferase of the tobacco hornworm, Manduca sexta (Sphingidae). J. Biol. Chem. 265: 868-873 (1990).

Rowsell EV, Carnie JA, Wahbi SD, Al-Tai AH, Rowsell KV. L-Serine dehydratase and L-serine-pyruvate aminotransferase activities in different animal species. Comp. Biochem. Physiol. [B] 63: 543-555 (1979).

Saez LP, Castillo F, Caballero FJ. Metabolism of L-phenylalanine and L-tyrosine by the phototrophic bacterium Rhodobacter capsulatus. Curr. Microbiol. 38: 51-56 (1999).

Saito K, Takagi Y, Ling HC, Takahashi H, Noji M. Molecular cloning, characterization and expression of cDNA encoding phosphoserine aminotransferase involved in phosphorylated pathway of serine biosynthesis from spinach. Plant Mol. Biol. 33: 359-366 (1997).

Sakagishi Y. Alanine aminotransferase. Nippon Rinsho 53: 1146-1150 (1995).

Salido EC, Li XM, Lu Y, Wang X, Santana A, Roy-Chowdhury N, Torres A, Shapiro LJ, Roy-Chowdhury J. Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer. Proc. Natl. Acad. Sci. U.S.A. 103: 18249-18254 (2006).

Salzmann D, Christen P, Mehta PK, Sandmeier E. Rates of evolution of pyridoxal-5'-phosphate-dependent enzymes. Biochem. Biophys. Res. Commun. 270: 576-580 (2000).

Sanchez E, Lopez-Lefebre LR, Garcia PC, Rivero RM, Ruiz JM, Romero L. Proline metabolism in response to highest nitrogen dosages in green bean plants (Phaseolus vulgaris L. cv. Strike). J. Plant Physiol. 158: 593-598 (2001).

Sanchez E, Ruiz JM, Romero L. Proline metabolism in response to nitrogen toxicity in fruit of French Bean plants (Phaseolus vulgaris L. cv Strike). Sci. Hortic. 93: 225-233 (2002).

Sanchez E, Ruiz JM, Romero L. The response of proline metabolism to nitrogen deficiency in pods and seeds of French bean (Phaseolus vulgaris L cv Strike) plants. J. Sci. Food Agric. 81: 1471-1475 (2001).

Sanchez-Medina F, Mayor F. L-glutamate 1-carboxylase and 4-aminobutyrate: 2-oxoglutarate aminotransferase in succulent plants. Rev. Esp. Fisiol. 26: 217-224 (1970).

Sandmeier E, Hale TI, Christen P. Multiple evolutionary origin of pyridoxal-5'-phosphate-dependent amino acid decarboxylases. Eur. J. Biochem. 221: 997-1002 (1994).

Sandorf I, Hollander-Czytko H. Jasmonate is involved in the induction of tyrosine aminotransferase and tocopherol biosynthesis in Arabidopsis thaliana. Planta 216: 173-179 (2002).

Sangwan I, O'Brian MR. Expression of the soybean (Glycine max) glutamate 1-semialdehyde aminotransferase gene in symbiotic root nodules. Plant Physiol. 102: 829-834 (1993).

Santana A, Salido E, Torres A, Shapiro LJ. Primary hyperoxaluria type 1 in the Canary Islands: a conformational disease due to I244T mutation in the P11L-containing alanine:glyoxylate aminotransferase. Proc. Natl. Acad. Sci. U.S.A. 100: 7277-7282 (2003).

Santos CV, Falcao IP, Pinto GC, Oliveira H, Loureiro J. Nutrient responses and glutamate and proline metabolism in sunflower plants and calli under Na2SO4 stress. J. Plant Nutr. Soil Sci.-Z. Pflanzenernahr. Bodenkd. 165: 366-372 (2002).

Sato T, Harada T, Ishizawa K. Stimulation of glycolysis in anaerobic elongation of pondweed (Potamogeton distinctus) turions. J. Exp. Bot. 53: 1847-1856 (2002).

Scandalios JG, Sorenson JC, Ott LA. Genetic control and intracellular localization of glutamate oxaloacetic transaminase in maize. Biochem. Genet. 13: 759-769 (1975).

Scapin G, Blanchard JS. Enzymology of bacterial lysine biosynthesis. Adv. Enzymol. Relat. Areas Mol. Biol. 72: 279-324 (1998).

Scarsdale JN, Radaev S, Kazanina G, Schirch V, Wright HT. Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate. J. Mol. Biol. 296: 155-168 (2000).

Schiavon M, Ertani A, Nardi S. Effects of an alfalfa protein hydrolysate on the gene expression and activity of enzymes of the tricarboxylic acid (TCA) cycle and nitrogen metabolism in Zea mays L. J. Agric. Food Chem. 56: 11800-11808 (2008).

Schmid D, Jaussi R, Christen P. Precursor of mitochondrial aspartate aminotransferase synthesized in Escherichia coli is complexed with heat-shock protein DnaK. Eur. J. Biochem. 208: 699-704 (1992).

Schmidt S, Stewart GR. Glycine metabolism by plant roots and its occurrence in Australian plant communities. Aust. J. Plant Physiol. 26: 253-264 (1999).

Schneider BL, Kiupakis AK, Reitzer LJ. Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli. J. Bacteriol. 180: 4278-4286 (1998).

Schneider G, Kack H, Lindqvist Y. The manifold of vitamin B6 dependent enzymes. Structure Fold. Des. 8: R1-R6 (2000).

Schultz CJ, Coruzzi GM. The aspartate aminotransferase gene family of Arabidopsis encodes isoenzymes localized to three distinct subcellular compartments. Plant J. 7: 61-75 (1995).

Schultz CJ, Hsu M, Miesak B, Coruzzi GM. Arabidopsis mutants define an in vivo role for isoenzymes of aspartate aminotransferase in plant nitrogen assimilation. Genetics 149: 491-499 (1998).

Schuster J, Binder S. The mitochondrial branched-chain aminotransferase (AtBCAT-1) is capable to initiate degradation of leucine, isoleucine and valine in almost all tissues in Arabidopsis thaliana. Plant Mol. Biol. 57: 241-254 (2005).

Schuster J, Knill T, Reichelt M, Gershenzon J, Binder S. BRANCHED-CHAIN AMINOTRANSFERASE4 is part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates in Arabidopsis. Plant Cell 18: 2664-2679 (2006).

Seebauer JR, Moose SP, Fabbri BJ, Crossland LD, Below FE. Amino acid metabolism in maize earshoots. Implications for assimilate preconditioning and nitrogen signaling. Plant Physiol. 136: 4326-4334 (2004).

Sekhar PN, Amrutha RN, Sangam S, Verma DP, Kishor PB. Biochemical characterization, homology modeling and docking studies of ornithine delta-aminotransferase--an important enzyme in proline biosynthesis of plants. J. Mol. Graph Model. 26: 709-719 (2007).

Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A. Bacterial variations on the methionine salvage pathway. BMC Microbiol. 4: 9 (2004).

Self JT, Spencer TE, Johnson GA, Hu JB, Bazer FW, Wu GY. Glutamine synthesis in the developing porcine placental. Biol. Reprod. 70: 1444-1451 (2004).

Sentoku N, Taniguchi M, Sugiyama T, Ishimaru K, Ohsugi R, Takaiwa F, Toki S. Analysis of the transgenic tobacco plants expressing Panicum miliaceum aspartate aminotransferase genes. Plant Cell Rep. 19: 598-603 (2000).

Shah SA, Shen BW, Brunger AT. Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition. Structure 5: 1067-1075 (1997).

Shasi Vardhan K, Pratap Rudra MP, Rao SL. Inhibition of tyrosine aminotransferase by beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, the Lathyrus sativus neurotoxin. J. Neurochem. 68: 2477-2484 (1997).

Shen BW, Hennig M, Hohenester E, Jansonius JN, Schirmer T. Crystal structure of human recombinant ornithine aminotransferase. J. Mol. Biol. 277: 81-102 (1998).

Sherwin AL. Neuroactive amino acids in focally epileptic human brain: a review. Neurochem. Res. 24: 1387-1395 (1999).

Shioi Y, Nagamine M, Sasa T. Purification and properties of L-alanine:4,5-dioxovalerate aminotransferase from Chlorella regularis. Arch. Biochem. Biophys. 234: 117-124 (1984).

Shrawat AK, Carroll RT, DePauw M, Taylor GJ, Good AG. Genetic engineering of improved nitrogen use efficiency in rice by the tissue-specific expression of alanine aminotransferase. Plant Biotechnol. J. 6: 722-732 (2008).

Shyur LF, Huang CC, Lo CP, Chiu CY, Chen YP, Wang SY, Chang ST. Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators. Phytochemistry 69: 1348-1358 (2008).

Siehl DL, Connelly JA, Conn EE. Tyrosine biosynthesis in Sorghum bicolor: characteristics of prephenate aminotransferase. Z. Naturforsch. [C] 41: 79-86 (1986).

Silvente S, Camas A, Lara M. Molecular cloning of the cDNA encoding aspartate aminotransferase from bean root nodules and determination of its role in nodule nitrogen metabolism. J. Exp. Bot. 54: 1545-1551 (2003).

Silverman RB, George C. Inactivation of gamma-aminobutyric acid aminotransferase by (Z)-4-amino-2-fluorobut-2-enoic acid. Biochemistry 27: 3285-3289 (1988).

Silverman RB, George C. Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (S,E)-4-amino-5-fluoropent-2-enoic acid. Biochem. Biophys. Res. Commun. 150: 942-946 (1988).

Smith IK. Purification and characterization of serine:glyoxylate aminotransferase from kidney bean (Phaseolus vulgaris). Biochim. Biophys. Acta 321: 156-164 (1973).

Smith MA, Kannangara CG, Grimm B, von Wettstein D. Characterization of glutamate-1-semialdehyde aminotransferase of Synechococcus. Steady-state kinetic analysis. Eur. J. Biochem. 202: 749-757 (1991).

Smith MA, King PJ, Grimm B. Transient-state kinetic analysis of Synechococcus glutamate 1-semialdehyde aminotransferase. Biochemistry 37: 319-329 (1998).

Solomon PS, Oliver RP. Evidence that gamma-aminobutyric acid is a major nitrogen source during Cladosporium fulvum infection of tomato. Planta 214: 414-420 (2002).

Song JT, Lu H, Greenberg JT. Divergent roles in Arabidopsis thaliana development and defense of two homologous genes, aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1, encoding novel aminotransferases. Plant Cell 16: 353-366 (2004).

Song JT, Lu H, McDowell JM, Greenberg JT. A key role for ALD1 in activation of local and systemic defenses in Arabidopsis. Plant J. 40: 200-212 (2004).

Stolz M, Dornemann D. Purification, characterization and N-terminal sequence of phosphoserine aminotransferase from the green alga Scenedesmus obliquus, mutant C-2 A'. Z. Naturforsch. [C] 49: 63-69 (1994).

Storici P, Capitani G, De Biase D, Moser M, John RA, Jansonius JN, Schirmer T. Crystal structure of GABA-aminotransferase, a target for antiepileptic drug therapy. Biochemistry 38: 8628-8634 (1999).

Storici P, Capitani G, M ller R, Schirmer T, Jansonius JN. Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. J. Mol. Biol. 285: 297-309 (1999).

Straffon MJ, Hynes MJ, Davis MA. Characterization of the ugatA gene of Ustilago maydis, isolated by homology to the gatA gene of Aspergillus nidulans. Curr. Genet. 29: 360-369 (1996).

Sturm N, Jortzik E, Mailu BM, Koncarevic S, Deponte M, Forchhammer K, Rahlfs S, Becker K. Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum. PLoS Pathog. 5: e1000383 (2009).

Sugio S, Kashima A, Kishimoto K, Peisach D, Petsko GA, Ringe D, Yoshimura T, Esaki N. Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination. Protein Eng. 11: 613-619 (1998).

Summers PS, Nolte KD, Cooper AJL, Borgeas H, Leustek T, Rhodes D, Hanson AD. Identification and stereospecificity of the first three enzymes of 3-dimethylsulfoniopropionate biosynthesis in a chlorophyte alga. Plant Physiol. 116: 369-378 (1998).

Sung BK, Cho JJ, Kim YT. Functional expression and characterization of C-terminal mutant of 4-aminobutyrate aminotransferase. J. Biochem. Mol. Biol. 32: 181-188 (1999).

Sung BK, Kim YT. Structural arrangement for functional requirements of brain recombinant 4-aminobutyrate aminotransferase. J. Biochem. Mol. Biol. 33: 43-48 (2000).

Suryawan A, Hawes JW, Harris RA, Shimomura Y, Jenkins AE, Hutson SM. A molecular model of human branched-chain amino acid metabolism. Am. J. Clin. Nutr. 68: 72-81 (1998).

Takada Y, Kaneko N, Esumi H, Purdue PE, Danpure CJ. Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon. Biochem. J. 268: 517-520 (1990).

Takada Y, Noguchi T. Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates. Biochem. J. 231: 157-163 (1985).

Takahashi M, Nakanishi H, Kawasaki S, Nishizawa NK, Mori S. Enhanced tolerance of rice to low iron availability in alkaline soils using barley nicotianamine aminotransferase genes. Nat. Biotechnol. 19: 466-469 (2001).

Takahashi M, Terada Y, Nakai I, Nakanishi H, Yoshimura E, Mori S, Nishizawa NK. Role of nicotianamine in the intracellular delivery of metals and plant reproductive development. Plant Cell 15: 1263-1280 (2003).

Takahashi M, Yamaguchi H, Nakanishi H, Shioiri T, Nishizawa NK, Mori S. Cloning two genes for nicotianamine aminotransferase, a critical enzyme in iron acquisition (Strategy II) in graminaceous plants. Plant Physiol. 121: 947-956 (1999).

Takahashi N, Yamada T. Pathways for amino acid metabolism by Prevotella intermedia and Prevotella nigrescens. Oral Microbiol. Immunol. 15: 96-102 (2000).

Taler D, Galperin M, Benjamin I, Cohen Y, Kenigsbuch D. Plant eR genes that encode photorespiratory enzymes confer resistance against disease. Plant Cell 16: 172-184 (2004).

Talwar R, Leelavathy V, Krishna Rao JV, Appaji Rao N, Savithri HS. Role of pro-297 in the catalytic mechanism of sheep liver serine hydroxymethyltransferase. Biochem. J. 350: 849-853 (2000).

Talwar R, Rao NA, Savithri HS. A change in reaction specificity of sheep liver serine hydroxymethyltransferase. Induction of NADH oxidation upon mutation of His230 to Tyr. Eur. J. Biochem. 267: 929-934 (2000).

Tam le T, Eymann C, Antelmann H, Albrecht D, Hecker M. Global gene expression profiling of Bacillus subtilis in response to ammonium and tryptophan starvation as revealed by transcriptome and proteome analysis. J. Mol. Microbiol. Biotechnol. 12: 121-130 (2007).

Tamaki N, Aoyama H, Kubo K, Ikeda T, Hama T. Purification and properties of beta-alanine aminotransferase from rabbit liver. J. Biochem. (Tokyo) 92: 1009-1017 (1982).

Tamaki N, Kaneko M, Mizota C, Kikugawa M, Fujimoto S. Purification, characterization and inhibition of D-3-aminoisobutyrate aminotransferase from the rat-liver. Eur. J. Biochem. 189: 39-45 (1990).

Tang YJ, Hwang JS, Wemmer DE, Keasling JD. The Shewanella oneidensis MR-1 fluxome under various oxygen conditions. Appl. Environ. Microbiol. 73: 718-729 (2007).

Taniguchi M, Kobe A, Kato M, Sugiyama T. Aspartate aminotransferase isozymes in Panicum miliaceum L., an NAD-malic enzyme-type C4 plant: comparison of enzymatic properties primary structures, and expression patterns. Arch. Biochem. Biophys. 318: 295-306 (1995).

Taniguchi M, Sawaki H, Sasakawa H, Hase T, Sugiyama T. Cloning and sequence analysis of cDNA encoding aspartate aminotransferase isozymes from Panicum miliaceum L., a C4 plant. Eur. J. Biochem. 204: 611-620 (1992).

Tarun AS, Theologis A. Complementation analysis of mutants of 1-aminocyclopropane- 1-carboxylate synthase reveals the enzyme is a dimer with shared active sites. J. Biol. Chem. 273: 12509-12514 (1998).

Temple SJ, Vance CP, Gantt JS. Glutamate synthase and nitrogen assimilation. Trends Plant Sci. 3: 51-56 (1998).

Ternan NG, Quinn JP. Phosphate starvation-independent 2-aminoethylphosphonic acid biodegradation in a newly isolated strain of Pseudomonas putida, NG2. Syst. Appl. Microbiol. 21: 346-352 (1998).

Tesch M, de Graaf AA, Sahm H. In vivo fluxes in the ammonium-assimilatory pathways in Corynebacterium glutamicum studied by 15N nuclear magnetic resonance. Appl. Environ. Microbiol. 65: 1099-1109 (1999).

Tharakan J, Hossenbocus A, Arthur MJ. Macromolecular aspartate aminotransferase. Eur. J. Gastroenterol. Hepatol. 10: 1055-1056 (1998).

Thiel J, Muller M, Weschke W, Weber H. Amino acid metabolism at the maternal-filial boundary of young barley seeds: a microdissection-based study. Planta 230: 205-213 (2009).

Thompson SG, Wong PT, Leong SF, McGeer EG. Regional distribution in rat brain of 1-pyrroline-5-carboxylate dehydrogenase and its localization to specific glial cells. J. Neurochem. 45: 1791-1796 (1985).

Titus DE, Becker WM. Investigation of the glyoxysome-peroxisome transition in germinating cucumber cotyledons using double-label immunoelectron microscopy. J. Cell Biol. 101: 1288-1299 (1985).

Tokunaga M, Nakano Y, Kitaoka S. Subcellular localization of the GABA-shunt enzymes in Euglena gracilis strain Z. J. Protozool. 26: 471-473 (1979).

Toney MD, Pascarella S, De Biase D. Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities. Protein Sci. 4: 2366-2374 (1995).

Torres N, Lopez G, De Santiago S, Hutson SM, Tovar AR. Dietary protein level regulates expression of the mitochondrial branched-chain aminotransferase in rats. J. Nutr. 128: 1368-1375 (1998).

Tsang EW, Yang J, Chang Q, Nowak G, Kolenovsky A, McGregor DI, Keller WA. Chlorophyll reduction in the seed of Brassica napus with a glutamate 1-semialdehyde aminotransferase antisense gene. Plant Mol. Biol. 51: 191-201 (2003).

Tsuji K, Yamasaki K, Yamanishi M, Kawakami M, Shirahama S. Risk of alanine aminotransferase flare-up among asymptomatic hepatitis C virus RNA carriers: A 10-year follow-up study. J. Gastroenterol. Hepatol. 16: 536-540 (2001).

Tunnicliff G. Chemical modification of bacterial 4-aminobutyrate aminotransferase by phenylglyoxal. J. Enzyme Inhib. 9: 309-316 (1995).

Tunnicliff G. Inhibition of 4-aminobutyrate aminotransferase from Pseudomonas fluorescens by ATP. Biochem. Mol. Biol. Int. 31: 41-47 (1993).

Tunnicliff G, Crites GJ. Chemical inactivation of bacterial GABA aminotransferase. Biochem. Mol. Biol. Int. 46: 43-54 (1998).

Turano FJ, Weisemann JM, Matthews BF. Identification and expression of a cDNA clone encoding aspartate aminotransferase in carrot. Plant Physiol. 100: 374-381 (1992).

Tyacke RJ, Contestabile R, Grimm B, Harwood JL, John RA. Reactions of glutamate semialdehyde aminotransferase (glutamate-1-semialdehyde 2,1 aminomutase) with vinyl and acetylenic substrate analogues analysed by rapid scanning spectrophotometry. Biochem. J. 309: 307-313 (1995).

Uno S, Kaito M, Kobayashi Y, Ishida S, Kato H, Gabazza E, Tamaki S, Ikoma J, Imoto I, Watanabe S, Adachi Y. Case report: Alanine aminotransferase deficiency detected in a patient with chronic hepatitis C. J. Gastroenterol. Hepatol. 13: 480-482 (1998).

Urrestarazu A, Vissers S, Iraqui I, Grenson M. Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination. Mol. Gen. Genet. 257: 230-237 (1998).

Vacca RA, Christen P, Malashkevich VN, Jansonius JN, Sandmeier E. Substitution of apolar residues in the active site of aspartate aminotransferase by histidine. Effects on reaction and substrate specificity. Eur. J. Biochem. 227: 481-487 (1995).

Vacca RA, Giannattasio S, Graber R, Sandmeier E, Marra E, Christen P. Active-site Arg --> Lys substitutions alter reaction and substrate specificity of aspartate aminotransferase. J. Biol. Chem. 272: 21932-21937 (1997).

Valdizan EM, Garcia AP, Armijo JA. Time course of the GABAergic effects of viGABAtrin: is the time course of brain GABA related to platelet GABA-transaminase inhibition? Epilepsia 40: 1062-1069 (1999).

van Brummelen AC, Olszewski KL, Wilinski D, Llinas M, Louw AI, Birkholtz LM. Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome and metabolome analyses. J. Biol. Chem. 284: 4635-4646 (2009).

Van Cauwenberghe OR, Shelp BJ. Biochemical characterization of partially purified GABA:pyruvate transaminase from Nicotiana tabacum. Phytochemistry 52: 575-581 (1999).

Van der Straeten D, Rodrigues-Pousada RA, Villarroel R, Hanley S, Goodman HM, Van Montagu M. Cloning, genetic mapping, and expression analysis of an Arabidopsis thaliana gene that encodes 1-aminocyclopropane-1-carboxylate synthase. Proc. Natl. Acad. Sci. U.S.A. 89: 9969-9973 (1992).

van der Zel A, Lam HM, Winkler ME. Extensive homology between the Escherichia coli K-12 SerC(PdxF) aminotransferase and a protein encoded by a progesterone-induced mRNA in rabbit and human endometria. Nucleic Acids Res. 17: 8379 (1989).

Vavilin DV, Vermaas WFJ. Regulation of the tetrapyrrole biosynthetic pathway leading to heme and chlorophyll in plants and cyanobacteria. Physiol. Plant. 115: 9-24 (2002).

Verdoy D, Coba DE LA Pena T, Redondo FJ, Lucas MM, Pueyo JJ. Transgenic Medicago truncatula plants that accumulate proline display nitrogen-fixing activity with enhanced tolerance to osmotic stress. Plant Cell Environ. 29: 1913-1923 (2006).

Verleur N, Elgersma Y, Van Roermund CW, Tabak HF, Wanders RJ. Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae. Eur. J. Biochem. 247: 972-980 (1997).

Verslues PE, Kim YS, Zhu JK. Altered ABA, proline and hydrogen peroxide in an Arabidopsis glutamate:glyoxylate aminotransferase mutant. Plant Mol. Biol. 64: 205-217 (2007).

Vidmar JJ, Schjoerring JK, Touraine B, Glass AD. Regulation of the hvst1 gene encoding a high-affinity sulfate transporter from Hordeum vulgare. Plant Mol. Biol. 40: 883-892 (1999).

Villanueva JA, Halsted CH. Hepatic transmethylation reactions in micropigs with alcoholic liver disease. Hepatology 39: 1303-1310 (2004).

Voellym R, Leisinger T. Role of 4-aminobutyrate aminotransferase in the arginine metabolism of Pseudomonas aeruginosa. J. Bacteriol. 128: 722-729 (1976).

Vozarova B, Stefan N, Lindsay RS, Saremi A, Pratley RE, Bogardus C, Tataranni PA. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 51: 1889-1895 (2002).

Wadsworth GJ, Gebhardt JS, Matthews BF. Characterization of a soybean cDNA clone encoding the mitochondrial isozyme of aspartate aminotransferase, AAT4. Plant Mol. Biol. 27: 1085-1095 (1995).

Wagemaker MJ, Eastwood DC, Welagen J, van der Drift C, Jetten MS, Burton K, Van Griensven LJ, Op den Camp HJ. The role of ornithine aminotransferase in fruiting body formation of the mushroom Agaricus bisporus. Mycol. Res. 111: 909-918 (2007).

Walker RP, Chen ZH, Tecsi LI, Famiani F, Lea PJ, Leegood RC. Phosphoenolpyruvate carboxykinase plays a role in interactions of carbon and nitrogen metabolism during grape seed development. Planta 210: 9-18 (1999).

Walton JD. HC-toxin. Phytochemistry 67: 1406-1413 (2006).

Ward DE, Kengen SW, van Der Oost J, de Vos WM. Purification and characterization of the alanine aminotransferase from the hyperthermophilic Archaeon pyrococcus furiosus and its role in alanine production. J. Bacteriol. 182: 2559-2566 (2000).

Watanabe N, Cherney MM, van Belkum MJ, Marcus SL, Flegel MD, Clay MD, Deyholos MK, Vederas JC, James MN. Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia. J. Mol. Biol. 371: 685-702 (2007).

Watford M, Chellaraj V, Ismat A, Brown P, Raman P. Hepatic glutamine metabolism. Nutrition 18: 301-303 (2002).

Watson NR, Peschke VM, Russell DA, Sachs MM. Analysis of L-alanine:2-oxoglutarate aminotransferase isozymes in maize. Biochem. Genet. 30: 371-383 (1992).

Watts RW. Alanine glyoxylate aminotransferase deficiency: biochemical and molecular genetic lessons from the study of a human disease. Adv. Enzyme Reg. 32: 309-327 (1992).

Wei H, Dhanaraj AL, Rowland LJ, Fu Y, Krebs SL, Arora R. Comparative analysis of expressed sequence tags from cold-acclimated and non-acclimated leaves of Rhododendron catawbiense Michx. Planta 221: 406-416 (2005).

Weigent DA, Nester EW. Regulation of histidinol phosphate aminotransferase synthesis by tryptophan in Bacillus subtilis. J. Bacteriol. 128: 202-211 (1976).

White MF, Vasquez J, Yang SF, Kirsch JF. Expression of apple 1-aminocyclopropane-1-carboxylate synthase in Escherichia coli: kinetic characterization of wild-type and active-site mutant forms. Proc. Natl. Acad. Sci. U.S.A. 91: 12428-12432 (1994).

Widmann M, Christen P. Comparison of folding rates of homologous prokaryotic and eukaryotic proteins. J. Biol. Chem. 275: 18619-18622 (2000).

Wightman F, Forest JC. Properties of plant aminotransferases. Phytochemistry 17: 1455-1471 (1978).

Wilkie MP, Claude JF, Cockshutt A, Holmes JA, Wang YS, Youson JH, Walsh PJ. Shifting patterns of nitrogen excretion and amino acid catabolism capacity during the life cycle of the sea lamprey (Petromyzon marinus). Physiol. Biochem. Zool. 79: 885-898 (2006).

Wilkie SE, Roper JM, Smith AG, Warren MJ. Isolation, characterisation and expression of a cDNA clone encoding plastid aspartate aminotransferase from Arabidopsis thaliana. Plant Mol. Biol. 27: 1227-1233 (1995).

Wilkie SE, Warren MJ. Recombinant expression, purification, and characterization of three isoenzymes of aspartate aminotransferase from Arabidopsis thaliana. Protein Expr. Purif. 12: 381-389 (1998).

Winefield CS, Farnden KJ, Reynolds PH, Marshall CJ. Evolutionary analysis of aspartate aminotransferases. J. Mol. Evol. 40: 455-463 (1995).

Winefield CS, Reddington BD, Jones WT, Reynolds PH, Farnden KJ. Cloning and characterization of a cDNA encoding aspartate aminotransferase-P1 from Lupinus angustifolius root tips. Plant Physiol. 104: 417-423 (1994).

Wingler A, Ann VJ, Lea PJ, Leegood RC. Serine:glyoxylate aminotransferase exerts no control on photosynthesis. J. Exp. Bot. 50: 719-722 (1999).

Wingler A, Quick WP, Bungard RA, Bailey KJ, Lea PJ, Leegood RC. The role of photorespiration during drought stress: an analysis utilizing barley mutants with reduced activities of photorespiratory enzymes. Plant Cell Environ. 22: 361-373 (1999).

Winiarska K, Bozko P, Lietz T, Bryla J. Importance of glutamate dehydrogenase stimulation for glucose and glutamine synthesis in rabbit renal tubules incubated with various amino acids. Acta Biochim. Pol. 45: 825-831 (1998).

Wu GY, Meininger CJ, Kelly K, Watford M, Morris M. A cortisol surge mediates the enhanced expression of pig intestinal pyrroline-5-carboxylate synthase during weaning. J. Nutr. 130: 1914-1919 (2000).

Wu SP, Liu C, Hwang TS, Chen JT, Tsai H. Improving the catalytic activity of phenylalanine aminotransferase of Escherichia coli by site-specific mutation. Ann. N.Y. Acad. Sci. 864: 561-564 (1998).

Xie G, Bonner CA, Jensen RA. A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling. J. Mol. Evol. 49: 108-121 (1999).

Xie G, Brettin TS, Bonner CA, Jensen RA. Mixed-function supraoperons that exhibit overall conservation, albeit shuffled gene organization, across wide intergenomic distances within eubacteria. Microb. Comp. Genomics 4: 5-28 (1999).

Xue HH, Fujie M, Sakaguchi T, Oda T, Ogawa H, Kneer NM, Lardy HA, Ichiyama A. Flux of the L-serine metabolism in rat liver. The predominant contribution of serine dehydratase. J. Biol. Chem. 274: 16020-16027 (1999).

Xue HH, Sakaguchi T, Fujie M, Ogawa H, Ichiyama A. Flux of the L-serine metabolism in rabbit, human, and dog livers. Substantial contributions of both mitochondrial and peroxisomal serine:pyruvate/alanine:glyoxylate aminotransferase. J. Biol. Chem. 274: 16028-16033 (1999).

Yamaguchi K, Nishimura M. Reduction to below threshold levels of glycolate oxidase activities in transgenic tobacco enhances photoinhibition during irradiation. Plant Cell Physiol. 41: 1397-1406 (2000).

Yang SQ, Koteish A, Lin HZ, Huang JW, Roskams T, Dawson V, Diehl AM. Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. Hepatology 39: 403-411 (2004).

Yano T, Oue S, Kagamiyama H. Directed evolution of an aspartate aminotransferase with new substrate specificities. Proc. Natl. Acad. Sci. U.S.A. 95: 5511-5515 (1998).

Yaronskaya E, Vershilovskaya I, Poers Y, Alawady AE, Averina N, Grimm B. Cytokinin effects on tetrapyrrole biosynthesis and photosynthetic activity in barley seedlings. Planta 224: 700-709 (2006).

Yaronskaya E, Ziemann V, Walter G, Averina N, Borner T, Grimm B. Metabolic control of the tetrapyrrole biosynthetic pathway for porphyrin distribution in the barley mutant albostrians. Plant J. 35: 512-522 (2003).

Yee J, Dennis PP. Isolation and characterization of a NADP-dependent glutamate dehydrogenase gene from the primitive eucaryote Giardia lamblia. J. Biol. Chem. 267: 7539-7544 (1992).

Yennawar NH, Islam MM, Conway M, Wallin R, Hutson SM. Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. J. Biol. Chem. 281: 39660-39671 (2006).

Yokota A, Suehiro S, Kitaoka S. Purification and some properties of mitochondrial glutamate:glyoxylate aminotransferase and mechanism of its involvement in glycolate pathway in Euglena gracilis z. Arch. Biochem. Biophys. 242: 507-514 (1985).

Yonaha K, Suzuki K, Toyama S. 4-Aminobutyrate:2-oxoglutarate aminotransferase of Streptomyces griseus: purification and properties. Eur. J. Biochem. 146: 101-106 (1985).

Yonaha K, Suzuki K, Toyama S. Streptomyces beta-alanine alpha-ketoglutarate aminotransferase, a novel omega-amino acid transaminase: purification, crystallization, and enzymologic properties. J. Biol. Chem. 260: 3265-3268 (1985).

Yonaha K, Toyama S. Mono-amine transamination catalyzed by omega-amino acid:pyruvate aminotransferase of Pseudomonas sp. F-126 Agric. & Biol. Chem. 42: 2363-2367 (1978).

Yonaha K, Toyama S. gamma-Aminobutyrate:alpha-ketoglutarate aminotransferase from Pseudomonas sp. F-126: purification, crystallization, and enzymologic properties. Arch. Biochem. Biophys. 200: 156-164 (1980).

Yoshida KM, Juni N, Hori SH. Molecular cloning and characterization of Drosophila ornithine aminotransferase gene. Genes Genet. Syst. 72: 9-17 (1997).

Yu C, Huang AH. Conversion of serine to glycerate in intact spinach leaf peroxisomes: role of malate dehydrogenase. Arch. Biochem. Biophys. 245: 125-133 (1986).

Yudkoff M, Daikhin Y, Nissim I, Nissim I. Acidosis and astrocyte amino acid metabolism. Neurochem. Int. 36: 329-339 (2000).

Zhang F, Sun X, Yi X, Zhang Y. Metabolic characteristics of recombinant Chinese hamster ovary cells expressing glutamine synthetase in presence and absence of glutamine. Cytotechnology 51: 21-28 (2006).

Zhang F, Yi XP, Sun XM, Zhang YX. Metabolism of recombinant CHO-GS cell reducing of toxic effect of ammonia. Sheng Wu Gong Cheng Xue Bao 22: 94-100 (2006).

Zhao G, Xia T, Ingram LO, Jensen RA. An allosterically insensitive class of cyclohexadienyl dehydrogenase from Zymomonas mobilis. Eur. J. Biochem. 212: 157-165 (1993).

Zhebentiaeva TN. The polymorphism and inheritance of aspartate aminotransferase in apricot. Tsitol. Genet. 34: 57-62 (2000).

Zhu XY, Jing Y, Chen GC, Wang SM, Zhang CL. Solute levels and osmoregulatory enzyme activities in reed plants adapted to drought and saline habitats. Plant Growth Regul. 41: 165-172 (2003).

Zwingmann C, Richter-Landsberg C, Leibfritz D. 13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes. Glia 34: 200-212 (2001).

Number of references = 571