Abd El-Mawla AM, Beerhues L 2002 Benzoic acid biosynthesis in cell cultures of Hypericum androsaemum. Planta 214: 727-733.

Abdel-Hamid AM, Attwood MM, Guest JR 2001 Pyruvate oxidase contributes to the aerobic growth efficiency of Escherichia coli. Microbiology 147: 1483-1498.

Abe I, Utsumi Y, Oguro S, Noguchi H 2004 The first plant type III polyketide synthase that catalyzes formation of aromatic heptaketide. FEBS Lett. 562: 171-176.

Alban C, Job D, Douce R 2000 Biotin metabolism in plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 51: 17-47.

Anderson MD, Che P, Song J, Nikolau BJ, Wurtele ES 1998 3-Methylcrotonyl-coenzyme A carboxylase is a component of the mitochondrial leucine catabolic pathway in plants. Plant Physiol. 118: 1127-1138.

Arruda P, Kemper EL, Papes F, Leite A 2000 Regulation of lysine catabolism in higher plants. Trends Plant Sci. 5: 324-330.

Baetens M, Legrain C, Boyen A, Glansdorff N 1998 Genes and enzymes of the acetyl cycle of arginine biosynthesis in the extreme thermophilic bacterium Thermus thermophilus HB27. Microbiology 144: 479-492.

Bao W, Sheldon PJ, Hutchinson CR 1999 Purification and properties of the Streptomyces peucetius DpsC beta-ketoacyl:acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis. Biochemistry 38: 9752-9757.

Bao X, Pollard M, Ohlrogge J 1998 The biosynthesis of erucic acid in developing embryos of Brassica rapa. Plant Physiol. 118: 183-190.

Bao X, Shorrosh BS, Ohlrogge JB 1997 Isolation and characterization of an Arabidopsis biotin carboxylase gene and its promoter. Plant Mol. Biol. 35: 539-550.

Baud S, Graham IA 2006 A spatiotemporal analysis of enzymatic activities associated with carbon metabolism in wild-type and mutant embryos of Arabidopsis using in situ histochemistry. Plant J. 46: 155-169.

Baud S, Guyon V, Kronenberger J, Wuilleme S, Miquel M, Caboche M, Lepiniec L, Rochat C 2003 Multifunctional acetyl-CoA carboxylase 1 is essential for very long chain fatty acid elongation and embryo development in Arabidopsis. Plant J. 33: 75-86.

Bederman IR, Kasumov T, Reszko AE, David F, Brunengraber H, Kelleher JK 2004 In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver. J. Biol. Chem. 279: 43217-43226.

Bederman IR, Reszko AE, Kasumov T, David F, Wasserman DH, Kelleher JK, Brunengraber H 2004 Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis. J. Biol. Chem. 279: 43207-43216.

Belkebir A, Paepe RD, Tremolieres A, Aid F, Benhassaine-Kesri G 2006 Sethoxydim affects lipid synthesis and acetyl-CoA carboxylase activity in soybean. J. Exp. Bot. 57: 3553-3562.

Blanchard CZ, Lee YM, Frantom PA, Waldrop GL 1999 Mutations at four active site residues of biotin carboxylase abolish substrate-induced synergism by biotin. Biochemistry 38: 3393-3400.

Brasen C, Urbanke C, Schonheit P 2005 A novel octameric AMP-forming acetyl-CoA synthetase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum. FEBS Lett. 579: 477-482.

Brock M, Maerker C, Schutz A, Volker U, Buckel W 2002 Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase. Eur. J. Biochem. 269: 6184-6194.

Brown TD, Jones-Mortimer MC, Kornberg HL 1977 The enzymic interconversion of acetate and acetyl-coenzyme A in Escherichia coli. J. Gen. Microbiol. 102: 327-336.

Buchanan BB, Arnon DI 1990 A reverse KREBS cycle in photosynthesis: consensus at last. Photosynth. Res. 24: 47-53.

Calder RB, Williams RS, Ramaswamy G, Rock CO, Campbell E, Unkles SE, Kinghorn JR, Jackowski S 1999 Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans. J. Biol. Chem. 274: 2014-2020.

Canovas M, Bernal V, Sevilla A, Iborra JL 2007 Salt stress effects on the central and carnitine metabolisms of Escherichia coli. Biotechnol. Bioeng. 96: 722-737.

Canovas M, Bernal V, Torroglosa T, Ramirez JL, Iborra JL 2003 Link between primary and secondary metabolism in the biotransformation of trimethylammonium compounds by Escherichia coli. Biotechnol. Bioeng. 84: 686-699.

Carrie C, Murcha MW, Millar AH, Smith SM, Whelan J 2007 Nine 3-ketoacyl-CoA thiolases (KATs) and acetoacetyl-CoA thiolases (ACATs) encoded by five genes in Arabidopsis thaliana are targeted either to peroxisomes or cytosol but not to mitochondria. Plant Mol. Biol. 63: 97-108.

Carvalho RA, Jeffrey FMH, Sherry AD, Malloy CR 1998 C-13 isotopomer analysis of glutamate by heteronuclear multiple quantum coherence total correlation spectroscopy (HMQC-TOCSY). FEBS Lett. 440: 382-386.

Chang Z, Vining LC 2002 Biosynthesis of sulfur-containing amino acids in Streptomyces venezuelae ISP5230: roles for cystathionine beta-synthase and transsulfuration. Microbiology 148: 2135-2147.

Chohnan S, Furukawa H, Fujio T, Nishihara H, Takamura Y 1997 Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. Appl. Environ. Microbiol. 63: 553-560.

Chohnan S, Izawa H, Nishihara H, Takamura Y 1998 Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses. Biosci. Biotechnol. Biochem. 62: 1122-1128.

Christensen B, Nielsen J 2000 Metabolic network analysis of Penicillium chrysogenum using 13C-labeled glucose. Biotechnol. Bioeng. 68: 652-659.

Cohen-Addad C, Faure M, Neuburger M, Ober R, Sieker L, Bourguignon J, Macherel D, Douce R 1997 Structural studies of the glycine decarboxylase complex from pea leaf mitochondria. Biochimie 79: 637-643.

daSilva PMFR, Eastmond PJ, Hill LM, Smith AM, Rawsthorne S 1997 Starch metabolism in developing embryos of oilseed rape. Planta 203: 480-487.

de Graaf AA, Striegel K, Wittig RM, Laufer B, Schmitz G, Wiechert W, Sprenger GA, Sahm H 1999 Metabolic state of Zymomonas mobilis in glucose-, fructose-, and xylose-fed continuous cultures as analysed by 13C- and 31P-NMR spectroscopy. Arch. Microbiol. 171: 371-385.

Delye C, Wang T, Darmency H 2002 An isoleucine-leucine substitution in chloroplastic acetyl-CoA carboxylase from green foxtail (Setaria viridis L. Beauv.) is responsible for resistance to the cyclohexanedione herbicide sethoxydim. Planta 214: 421-427.

Desvaux M 2005 Clostridium cellulolyticum: model organism of mesophilic cellulolytic clostridia. FEMS Microbiol. Rev. 29: 741-764.

Disch A, Hemmerlin A, Bach TJ, Rohmer M 1998 Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells. Biochem. J. 331: 615-621.

Dudareva N, D'Auria JC, Nam KH, Raguso RA, Pichersky E 1998 Acetyl-CoA:benzylalcohol acetyltransferase--an enzyme involved in floral scent production in Clarkia breweri. Plant J. 14: 297-304.

Ebel J, Schmidt WE, Loyal R 1984 Phytoalexin synthesis in soybean cells: elicitor induction of phenylalanine ammonia-lyase and chalcone synthase mRNAs and correlation with phytoalexin accumulation. Arch. Biochem. Biophys. 232: 240-248.

Eccleston VS, Ohlrogge JB 1998 Expression of lauroyl-acyl carrier protein thioesterase in Brassica napus seeds induces pathways for both fatty acid oxidation and biosynthesis and implies a set point for triacylglycerol accumulation. Plant Cell 10: 613-622.

Eckardt NA 2005 Peroxisomal citrate synthase provides exit route from fatty acid metabolism in oilseeds. Plant Cell 17: 1863-1865.

Egli MA, Gengenbach BG, Gronwald JW, Somers DA, Wyse DL 1993 Characterization of maize acetyl-coenzyme A carboxylase. Plant Physiol. 101: 499-506.

Eisenreich W, Strauss G, Werz U, Fuchs G, Bacher A 1993 Retrobiosynthetic analysis of carbon fixation in the phototrophic eubacterium Chloroflexus aurantiacus. Eur. J. Biochem. 215: 619-632.

Falk KL, Guerra DJ 1993 Coenzyme A biosynthesis in plants: partial purification and characterization of pantothenate kinase from spinach. Arch. Biochem. Biophys. 301: 424-430.

Falk KL, Vogel C, Textor S, Bartram S, Hick A, Pickett JA, Gershenzon J 2004 Glucosinolate biosynthesis: demonstration and characterization of the condensing enzyme of the chain elongation cycle in Eruca sativa. Phytochemistry 65: 1073-1084.

Fatland BL, Ke J, Anderson MD, Mentzen WI, Cui LW, Allred CC, Johnston JL, Nikolau BJ, Wurtele ES 2002 Molecular characterization of a heteromeric ATP-citrate lyase that generates cytosolic acetyl-coenzyme A in Arabidopsis. Plant Physiol. 130: 740-756.

Fatland BL, Nikolau BJ, Wurtele ES 2005 Reverse genetic characterization of cytosolic acetyl-CoA generation by ATP-citrate lyase in Arabidopsis. Plant Cell 17: 182-203.

Ferry JG 1999 Enzymology of one-carbon metabolism in methanogenic pathways. FEMS Microbiol. Rev. 23: 13-38.

Filipe CD, Daigger GT, Grady CP Jr 2001 A metabolic model for acetate uptake under anaerobic conditions by glycogen accumulating organisms: Stoichiometry, kinetics, and the effect of pH. Biotechnol. Bioeng. 76: 17-31.

Fonseca CP, Jones JG, Carvalho RA, Jeffrey FM, Montezinho LP, Geraldes CF, Castro MM 2005 Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis. Neurochem. Int. 47: 385-393.

Frick O, Wittmann C 2005 Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative 13C flux analysis. Microb. Cell. Fact. 4: 30.

Geigenberger P, Kolbe A, Tiessen A 2005 Redox regulation of carbon storage and partitioning in response to light and sugars. J. Exp. Bot. 56: 1469-1479.

Gerhardt B, Fischer K, Balkenhohl TJ, Pohnert G, Kuhn H, Wasternack C, Feussner I 2005 Lipoxygenase-mediated metabolism of storage lipids in germinating sunflower cotyledons and beta-oxidation of (9Z,11E,13S)-13-hydroxy-octadeca-9,11-dienoic acid by the cotyledonary glyoxysomes. Planta 220: 919-930.

Grahame DA 2003 Acetate C-C bond formation and decomposition in the anaerobic world: the structure of a central enzyme and its key active-site metal cluster. Trends Biochem. Sci. 28: 221-224.

Graser G, Oldham NJ, Brown PD, Temp U, Temp U, Gershenzon J 2001 The biosynthesis of benzoic acid glucosinolate esters in Arabidopsis thaliana. Phytochemistry 57: 23-32.

Graser G, Schneider B, Oldham NJ, Gershenzon J 2000 The methionine chain elongation pathway in the biosynthesis of glucosinolates in Eruca sativa (Brassicaceae). Arch. Biochem. Biophys. 378: 411-419.

Gulick AM, Starai VJ, Horswill AR, Homick KM, Escalante-Semerena JC 2003 The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A. Biochemistry 42: 2866-2873.

Hagelstein P, Schultz G 1993 Leucine synthesis in spinach chloroplasts: partial characterization of 2-isopropylmalate synthase. Biol. Chem. Hoppe Seyler 374: 1105-1108.

Halford NG, Paul MJ 2003 Carbon metabolite sensing and signalling. Plant Biotechnol. J. 1: 381-398.

Halvorsen O, Skrede S 1982 Regulation of the biosynthesis of CoA at the level of pantothenate kinase. Eur. J. Biochem. 124: 211-215.

Hansen TA 1994 Metabolism of sulfate-reducing prokaryotes. Antonie Van Leeuwenhoek 66: 165-185.

Harwood JL, Ramli US, Page RA, Quant PA 1999 Modelling lipid metabolism in plants: a slippery problem? Biochem. Soc. Trans. 27: 285-289.

Hochuli M, Szyperski T, Wuthrich K 2000 Deuterium isotope effects on the central carbon metabolism of Escherichia coli cells grown on a D2O-containing minimal medium. J. Biomol. NMR 17: 33-42.

Hong SH, Park SJ, Moon SY, Park JP, Lee SY 2003 In silico prediction and validation of the importance of the Entner-Doudoroff pathway in poly(3-hydroxybutyrate) production by metabolically engineered Escherichia coli. Biotechnol. Bioeng. 83: 854-863.

Houmiel KL, Slater S, Broyles D, Casagrande L, Colburn S, Gonzalez K, Mitsky TA, Reiser SE, Shah D, Taylor NB, Tran M, Valentin HE, Gruys KJ 1999 Poly(beta-hydroxybutyrate) production in oilseed leukoplasts of Brassica napus. Planta 209: 547-550.

Huang S, Sirikhachornkit A, Faris JD, Su X, Gill BS, Haselkorn R, Gornicki P 2002 Phylogenetic analysis of the acetyl-CoA carboxylase and 3-phosphoglycerate kinase loci in wheat and other grasses. Plant Mol. Biol. 48: 805-820.

Hugler M, Krieger RS, Jahn M, Fuchs G 2003 Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation. Eur. J. Biochem. 270: 736-744.

Huth W, Rolle S, Wunderlich I 2002 Turnover of matrix proteins in mammalian mitochondria. Biochem. J. 364: 275-284.

Inoue K, Noji M, Saito K 1999 Determination of the sites required for the allosteric inhibition of serine acetyltransferase by L-cysteine in plants. Eur. J. Biochem. 266: 220-227.

Ismail W, El-Said Mohamed M, Wanner BL, Datsenko KA, Eisenreich W, Rohdich F, Bacher A, Fuchs G 2003 Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli. Eur. J. Biochem. 270: 3047-3054.

Jackowski S, Rock CO 1986 Consequences of reduced intracellular coenzyme A content in Escherichia coli. J. Bacteriol. 166: 866-871.

Jones AL, Gane AM, Herbert D, Willey DL, Rutter AJ, Kille P, Dancer JE, Harwood JL 2003 beta-Ketoacyl-acyl carrier protein synthase III from pea (Pisum sativum L.): properties, inhibition by a novel thiolactomycin analogue and isolation of a cDNA clone encoding the enzyme. Planta 216: 752-761.

Jucker BM, Lee JY, Shulman RG 1998 In vivo 13C NMR measurements of hepatocellular tricarboxylic acid cycle flux. J. Biol. Chem. 273: 12187-12194.

Jung Y, Park J, Lee Y 2000 Metabolic engineering of Alcaligenes eutrophus through the transformation of cloned phbCAB genes for the investigation of the regulatory mechanism of polyhydroxyalkanoate biosynthesis. Enzyme Microb. Technol. 26: 201-208.

Katz J, Wals P, Lee WNP 1993 Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate. J. Biol. Chem. 268: 25509-25521.

Kawashima CG, Berkowitz O, Hell R, Noji M, Saito K 2005 Characterization and expression analysis of a serine acetyltransferase gene family involved in a key step of the sulfur assimilation pathway in Arabidopsis. Plant Physiol. 137: 220-230.

Ke J, Behal RH, Back SL, Nikolau BJ, Wurtele ES, Oliver DJ 2000 The role of pyruvate dehydrogenase and acetyl-coenzyme A synthetase in fatty acid synthesis in developing Arabidopsis seeds. Plant Physiol. 123: 497-508.

Kelley M, Vessey DA 1986 Interaction of 2,4-dichlorophenoxyacetate (2,4-D) and 2,4,5-trichlorophenoxyacetate (2,4,5-T) with the acyl-CoA: amino acid N-acyltransferase enzymes of bovine liver mitochondria. Biochem. Pharmacol. 35: 289-295.

Klaus D, Ohlrogge JB, Neuhaus HE, Dormann P 2004 Increased fatty acid production in potato by engineering of acetyl-CoA carboxylase. Planta 219: 389-396.

Knappe J, Sawers G 1990 A radical-chemical route to acetyl-CoA: the anaerobically induced pyruvate formate-lyase system of Escherichia coli. FEMS Microbiol. Rev. 6: 383-398.

Kode V, Mudd EA, Iamtham S, Day A 2005 The tobacco plastid accD gene is essential and is required for leaf development. Plant J. 44: 237-244.

Kouchi H, Hata S 1995 GmN56, a novel nodule-specific cDNA from soybean root nodules encodes a protein homologous to isopropylmalate synthase and homocitrate synthase. Mol. Plant Microbe Interact. 8: 172-176.

Kromer S, Gardestrom P, Samuelsson G 1996 Regulation of the supply of oxaloacetate for mitochondrial metabolism via phosphoenolpyruvate carboxylase in barley leaf protoplasts. II. Effects of metabolites on PEPC activity at different activation states of the protein. Biochim. Biophys. Acta 1289: 351-361.

Langlade NB, Messerli G, Weisskopf L, Plaza S, Tomasi N, Smutny J, Neumann G, Martinoia E, Massonneau A 2002 ATP citrate lyase: cloning, heterologous expression and possible implication in root organic acid metabolism and excretion. Plant Cell Environ. 25: 1561-1569.

Li M, Ho PY, Yao S, Shimizu K 2006 Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by (13)C-labeling experiments. J. Biotechnol. 122: 254-266.

Lin M, Behal R, Oliver DJ 2003 Disruption of plE2, the gene for the E2 subunit of the plastid pyruvate dehydrogenase complex, in Arabidopsis causes an early embryo lethal phenotype. Plant Mol. Biol. 52: 865-872.

Logemann E, Tavernaro A, Schulz W, Somssich IE, Hahlbrock K 2000 UV light selectively coinduces supply pathways from primary metabolism and flavonoid secondary product formation in parsley. Proc. Natl. Acad. Sci. U.S.A. 97: 1903-1907.

Loscher R, Heide L 1994 Biosynthesis of p-hydroxybenzoate from p-coumarate and p-coumaroyl-coenzyme A in cell-free extracts of Lithospermum erythrorhizon cell cultures. Plant Physiol. 106: 271-279.

Lu D, Mulder H, Zhao P, Burgess SC, Jensen MV, Kamzolova S, Newgard CB, Sherry AD 2002 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proc. Natl. Acad. Sci. U.S.A. 99: 2708-2713.

Maaheimo H, Fiaux J, Cakar ZP, Bailey JE, Sauer U, Szyperski T 2001 Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional C-13 labeling of common amino acids. Eur. J. Biochem. 268: 2464-2479.

Mancuso A, Sharfstein ST, Tucker SN, Clark DS, Blanch HW 1994 Examination of primary metabolic pathways in a murine hybridoma with C-13 nuclear magnetic resonance spectroscopy. Biotechnol. Bioeng. 44: 563-585.

Martin G, Chauvin MF, Baverel G 1997 Model applicable to NMR studies for calculating flux rates in five cycles involved in glutamate metabolism. J. Biol. Chem. 272: 4717-428.

Mellema S, Eichenberger W, Rawyler A, Suter M, Tadege M, Kuhlemeier C 2002 The ethanolic fermentation pathway supports respiration and lipid biosynthesis in tobacco pollen. Plant J. 30: 329-336.

Menendez C, Bauer Z, Huber H, Gad'on N, Stetter KO, Fuchs G 1999 Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation. J. Bacteriol. 181: 1088-1098.

Menzel K, Ahrens K, Zeng A, Deckwer W 1998 Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: IV. Enzymes and fluxes of pyruvate metabolism. Biotechnol. Bioeng. 60: 617-626.

Morita H, Noguchi H, Schroder J, Abe I 2001 Novel polyketides synthesized with a higher plant stilbene synthase. Eur. J. Biochem. 268: 3759-3766.

Musfeldt M, Selig M, Schonheit P 1999 Acetyl coenzyme A synthetase (ADP forming) from the hyperthermophilic archaeon Pyrococcus furiosus. J. Bacteriol. 181: 5885-5888.

Nagegowda DA, Ramalingam S, Hemmerlin A, Bach TJ, Chye ML 2005 Brassica juncea HMG-CoA synthase: localization of mRNA and protein. Planta 221: 844-856.

Nam KH, Dudareva N, Pichersky E 1999 Characterization of benzylalcohol acetyltransferases in scented and non-scented Clarkia species. Plant Cell Physiol. 40: 916-923.

Nandi DL, Lucas SV, Webster LT Jr 1979 Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization. J. Biol. Chem. 254: 7230-7237.

Nawrath C, Poirier Y, Somerville C 1994 Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids of Arabidopsis thaliana results in high levels of polymer accumulation. Proc. Natl. Acad. Sci. U.S.A. 91: 12760-12764.

Nishimaki T, Yamanaka H, Mizugaki M 1986 Acetyl-CoA-dependent chain elongation of fatty acids in Escherichia coli K-12. J. Biochem. (Tokyo) 99: 365-374.

Nissim I, Daikhin Y, Nissim I, Luhovyy B, Horyn O, Wehrli SL, Yudkoff M 2006 Agmatine stimulates hepatic fatty acid oxidation: a possible mechanism for up-regulation of ureagenesis. J. Biol. Chem. 281: 8486-8496.

Noji M, Inoue K, Kimura N, Gouda A, Saito K 1998 Isoform-dependent differences in feedback regulation and subcellular localization of serine acetyltransferase involved in cysteine biosynthesis from Arabidopsis thaliana. J. Biol. Chem. 273: 32739-32745.

Nomikos TN, Iatrou C, Demopoulos CA 2003 Acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (lyso-PAF AT) activity in cortical and medullary human renal tissue. Eur. J. Biochem. 270: 2992-3000.

Nordling E, Jornvall H, Persson B 2002 Medium-chain dehydrogenases/reductases (MDR). Family characterizations including genome comparisons and active site modeling. Eur. J. Biochem. 269: 4267-4276.

Noronha SB, Yeh HJ, Spande TF, Shiloach J 2000 Investigation of the TCA cycle and the glyoxylate shunt in Escherichia coli BL21 and JM109 using 13C-NMR/MS. Biotechnol. Bioeng. 68: 316-327.

Oeljeklaus S, Fischer K, Gerhardt B 2002 Glyoxysomal acetoacetyl-CoA thiolase and 3-oxoacyl-CoA thiolase from sunflower cotyledons. Planta 214: 597-607.

Ohlrogge JB, Jaworski JG 1997 Regulation of fatty acid synthesis. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48: 109-136.

op den Camp RG, Kuhlemeier C 1997 Aldehyde dehydrogenase in tobacco pollen. Plant Mol. Biol. 35: 355-365.

Park SM, Shaw-Reid C, Sinskey AJ, Stephanopoulos G 1997 Elucidation of anaplerotic pathways in Corynebacterium glutamicum via 13C-NMR spectroscopy and GC-MS. Appl. Microbiol. Biotechnol. 47: 430-440.

Pereto JG, Velasco AM, Becerra A, Lazcano A 1999 Comparative biochemistry of CO2 fixation and the evolution of autotrophy. Int. Microbiol. 2: 3-10.

Phue JN, Noronha SB, Hattacharyya R, Wolfe AJ, Shiloach J. 2005 Glucose metabolism at high density growth of E. coli B and E. coli K: differences in metabolic pathways are responsible for efficient glucose utilization in E. coli B as determined by microarrays and Northern blot analyses. Biotechnol. Bioeng. 90: 805-820.

Poole P, Allaway D 2000 Carbon and nitrogen metabolism in Rhizobium. Adv. Microb. Physiol. 43: 117-163.

Price LJ, Moss SR, Cole DJ, Harwood JL 2004 Graminicide resistance in a blackgrass (Alopecurus myosuroides) population correlates with insensitivity of acetyl-CoA carboxylase. Plant Cell Environ. 27: 15-26.

Pronk JT, Yde Steensma H, Van Dijken JP 1996 Pyruvate metabolism in Saccharomyces cerevisiae. Yeast 12: 1607-1633.

Pua EC, Chandramouli S, Han P, Liu P 2003 Malate synthase gene expression during fruit ripening of Cavendish banana (Musa acuminata cv. Williams). J. Exp. Bot. 54: 309-316.

Rajgarhia VB, Priestley ND, Strohl WR 2001 The product of dpsC confers starter unit fidelity upon the daunorubicin polyketide synthase of Streptomyces sp. strain C5. Metab. Eng. 3: 49-63.

Rangasamy D, Ratledge C 2000 Genetic enhancement of fatty acid synthesis by targeting rat liver ATP:citrate lyase into plastids of tobacco. Plant Physiol. 122: 1231-1238.

Raushel FM, Thoden JB, Holden HM 2003 Enzymes with molecular tunnels. Acc. Chem. Res. 36: 539-548.

Rawsthorne S 2002 Carbon flux and fatty acid synthesis in plants. Prog. Lipid Res. 41: 182-196.

Reshetnikov AS, Mustakhimov II, Khmelenina VN, Trotsenko YA 2005 Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the halotolerant methanotroph Methylomicrobium alcaliphilum 20Z. Biochemistry (Mosc.) 70: 878-883.

Rock CO, Calder RB, Karim MA, Jackowski S 2000 Pantothenate kinase regulation of the intracellular concentration of coenzyme A. J. Biol. Chem. 275: 1377-1383.

Rock CO, Karim MA, Zhang YM, Jackowski S 2002 The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes. Gene 291: 35-43.

Rodriguez-Caso C, Montanez R, Cascante M, Sanchez-Jimenez F, Medina MA 2006 Mathematical modeling of polyamine metabolism in mammals. J. Biol. Chem. 281: 21799-21812.

Rubio S, Larson TR, Gonzalez-Guzman M, Alejandro S, Graham IA, Serrano R, Rodriguez PL 2006 An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar-dependent for seedling establishment. Plant Physiol. 140: 830-843.

Samappito S, Page J, Schmidt J, De-Eknamkul W, Kutchan TM 2002 Molecular characterization of root-specific chalcone synthases from Cassia alata. Planta 216: 64-71.

Samappito S, Page JE, Schmidt J, De-Eknamkul W, Kutchan TM 2003 Aromatic and pyrone polyketides synthesized by a stilbene synthase from Rheum tataricum. Phytochemistry 62: 313-323.

Sasaki Y, Nagano Y 2004 Plant acetyl-CoA carboxylase: structure, biosynthesis, regulation, and gene manipulation for plant breeding. Biosci. Biotechnol. Biochem. 68: 1175-1184.

Savage LJ, Ohlrogge JB 1999 Phosphorylation of pea chloroplast acetyl-CoA carboxylase. Plant J. 18: 521-527.

Sawers G, Watson G 1998 A glycyl radical solution: oxygen-dependent interconversion of pyruvate formate-lyase. Mol. Microbiol. 29: 945-54.

Schneider S, Mohamed ME, Fuchs G 1997 Anaerobic metabolism of L-phenylalanine via benzoyl-CoA in the denitrifying bacterium Thauera aromatica. Arch. Microbiol. 168: 310-320.

Schwender J, Goffman F, Ohlrogge JB, Shachar-Hill Y 2004 Rubisco without the Calvin cycle improves the carbon efficiency of developing green seeds. Nature 432: 779-782.

Schwender J, Ohlrogge JB 2002 Probing in vivo metabolism by stable isotope labeling of storage lipids and proteins in developing Brassica napus embryos. Plant Physiol. 130: 347-361.

Schwender J, Seemann M, Lichtenthaler HK, Rohmer M 1996 Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus. Biochem. J. 316: 73-80.

Shalit M, Katzir N, Tadmor Y, Larkov O, Burger Y, Shalekhet F, Lastochkin E, Ravid U, Amar O, Edelstein M, Karchi Z, Lewinsohn E 2001 Acetyl-Coa: alcohol acetyltransferase activity and aroma formation in ripening melon fruits. J. Agric. Food Chem. 49: 794-799.

Shaner DL 2004 Herbicide safety relative to common targets in plants and mammals. Pest Manag. Sci. 60: 17-24.

Sharkey TD, Loreto F, Delwiche CF, Treichel IW 1991 Fractionation of carbon isotopes during biogenesis of atmospheric isoprene. Plant Physiol. 97: 463-466.

Shi H, Nikawa J, Shimizu K 1999 Effect of modifying metabolic network on poly-3-hydroxybutyrate biosynthesis in recombinant Escherichia coli. J. Biosci. Bioeng. 87: 666-677.

Shin M, Sano K, Umezawa C 1991 Metabolism of tryptophan to niacin in Saccharomyces uvarum. J. Nutr. Sci. Vitaminol. (Tokyo) 37: 269-283.

Shorrosh BS, Roesler KR, Shintani D, van de Loo FJ, Ohlrogge JB 1995 Structural analysis, plastid localization, and expression of the biotin carboxylase subunit of acetyl-coenzyme A carboxylase from tobacco. Plant Physiol. 108: 805-812.

Shukla AK, Shasany AK, Gupta MM, Khanuja SP 2006 Transcriptome analysis in Catharanthus roseus leaves and roots for comparative terpenoid indole alkaloid profiles. J. Exp. Bot. 57: 3921-3932.

Simpson NE, Han Z, Berendzen KM, Sweeney CA, Oca-Cossio JA, Constantinidis I, Stacpoole PW 2006 Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate. Mol. Genet. Metab. 89: 97-105.

Strauss E, Begley TP 2002 The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme A, a coenzyme A antimetabolite. J. Biol. Chem. 277: 48205-48209.

Suzuki H, Sawada S, Watanabe K, Nagae S, Yamaguchi MA, Nakayama T, Nishino T 2004 Identification and characterization of a novel anthocyanin malonyltransferase from scarlet sage (Salvia splendens) flowers: an enzyme that is phylogenetically separated from other anthocyanin acyltransferases. Plant J. 38: 994-1003.

Tadege M, Kuhlemeier C 1997 Aerobic fermentation during tobacco pollen development. Plant Mol. Biol. 35: 343-354.

Takamura Y, Nomura G 1988 Changes in the intracellular concentration of acetyl-CoA and malonyl-CoA in relation to the carbon and energy metabolism of Escherichia coli K12. J. Gen. Microbiol. 134: 2249-2253.

Tang Y, Pingitore F, Mukhopadhyay A, Phan R, Hazen TC, Keasling JD 2007 Pathway confirmation and flux analysis of central metabolic pathways in Desulfovibrio vulgaris Hildenborough using GC-MS and FT-ICR mass spectrometry. J. Bacteriol. 189: 940-949.

Textor S, Bartram S, Kroymann J, Falk KL, Hick A, Pickett JA, Gershenzon J 2004 Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain-elongation cycle. Planta 218: 1026-1035.

Textor S, Wendisch VF, de Graaf AA, Muller U, Linder MI, Linder D, Buckel W 1997 Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria. Arch. Microbiol. 168: 428-436.

Thelen JJ, Ohlrogge JB 2002 The multisubunit acetyl-CoA carboxylase is strongly associated with the chloroplast envelope through non-ionic interactions to the carboxyltransferase subunits. Arch. Biochem. Biophys. 400: 245-257.

Thykaer J, Christensen B, Nielsen J 2002 Metabolic network analysis of an adipoyl-7-ADCA-producing strain of Penicillium chrysogenum: elucidation of adipate degradation. Metab. Eng. 4: 151-158.

Toroser D, Huber SC 1998 3-Hydroxy-3-methylglutaryl-coenzyme A reductase kinase and sucrose-phosphate synthase kinase activities in cauliflower florets: Ca2+ dependence and substrate specificities. Arch. Biochem. Biophys. 355: 291-300.

Tovar-Mendez A, Miernyk JA, Randall DD 2003 Regulation of pyruvate dehydrogenase complex activity in plant cells. Eur. J. Biochem. 270: 1043-1049.

Tran-Dinh S, Beganton F, Nguyen TT, Bouet F, Herve M 1996 Mathematical model for evaluating the Krebs cycle flux with non-constant glutamate-pool size by 13C-NMR spectroscopy. Evidence for the existence of two types of Krebs cycles in cells. Eur. J. Biochem. 242: 220-227.

Tran-Dinh S, Hoerter JA, Mateo P, Gyppaz F, Herve M 1998 13C-NMR spectroscopic evaluation of the citric acid cycle flux in conditions of high aspartate transaminase activity in glucose-perfused rat hearts. Biochimie 80: 1013-1024.

Vadali RV, Bennett GN, San KY 2004 Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli. Metab. Eng. 6: 133-139.

Vadali RV, Bennett GN, San KY 2004 Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli. Metab. Eng. 6: 294-299.

Valentin HE, Reiser S, Gruys KJ 2000 Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) formation from gamma-aminobutyrate and glutamate. Biotechnol. Bioeng. 67: 291-299.

Vallari DS, Jackowski S 1988 Biosynthesis and degradation both contribute to the regulation of coenzyme A content in Escherichia coli. J. Bacteriol. 170: 3961-3966.

Vallari DS, Jackowski S, Rock CO 1987 Regulation of pantothenate kinase by coenzyme A and its thioesters. J. Biol. Chem. 262: 2468-2471.

van Wegen RJ, Lee SY, Middelberg AP 2001 Metabolic and kinetic analysis of poly(3-hydroxybutyrate) production by recombinant Escherichia coli. Biotechnol. Bioeng. 74: 70-81.

Vigeolas H, van Dongen JT, Waldeck P, Huhn D, Geigenberger P 2003 Lipid storage metabolism is limited by the prevailing low oxygen concentrations within developing seeds of oilseed rape. Plant Physiol. 133: 2048-2060.

Voegele RT, Mitsch MJ, Finan TM 1999 Characterization of two members of a novel malic enzyme class. Biochim. Biophys. Acta 1432: 275-285.

Wang XG, Roderick SL 1999 Expression, purification, crystallization and preliminary X-ray data of Escherichia coli galactoside acetyltransferase. Acta Crystallogr. D. Biol. Crystallogr. 55: 1955-1957.

Wong DA, Bassilian S, Lim S, Lee WN 2004 Coordination of peroxisomal beta-oxidation and fatty acid elongation in HepG2 cells. J. Biol. Chem. 279: 41302-41309.

Wood HG 1991 Life with CO or CO2 and H2 as a source of carbon and energy. FASEB J. 5: 156-163.

Woolridge DP, Martinez JD, Stringer DE, Gerner EW 1999 Characterization of a novel spermidine/spermine acetyltransferase, BltD, from Bacillus subtilis. Biochem. J. 340: 753-758.

Yanai Y, Kawasaki T, Shimada H, Wurtele ES, Nikolau BJ, Ichikawa N 1995 Genomic organization of 251 kDa acetyl-CoA carboxylase genes in Arabidopsis: tandem gene duplication has made two differentially expressed isozymes. Plant Cell Physiol. 36: 779-787.

Yang LM, Lamppa G 1996 Identification of a chloroplast coenzyme A-binding protein related to the peroxisomal thiolases. Plant Physiol. 112: 1641-1647.

Yang YT, Bennett GN, San KY 1999 Effect of inactivation of nuo and ackA-pta on redistribution of metabolic fluxes in Escherichia coli. Biotechnol. Bioeng. 65: 291-297.

Yang YT, Bennett GN, San KY 2001 The effects of feed and intracellular pyruvate levels on the redistribution of metabolic fluxes in Escherichia coli. Metab. Eng. 3: 115-123.

Yang YT, San KY, Bennett GN 1999 Redistribution of metabolic fluxes in Escherichia coli with fermentative lactate dehydrogenase overexpression and deletion. Metab. Eng. 1: 141-152.

Yao X, Soden C Jr, Summers MF, Beckett D 1999 Comparison of the backbone dynamics of the apo- and holo-carboxy-terminal domain of the biotin carboxyl carrier subunit of Escherichia coli acetyl-CoA carboxylase. Protein Sci. 8: 307-317.

Yu J, Wang J 2001 Metabolic flux modeling of detoxification of acetic acid by Ralstonia eutropha at slightly alkaline pH levels. Biotechnol. Bioeng. 73: 458-464.

Yudkoff M, Daikhin Y, Nissim I, Nissim I 2000 Acidosis and astrocyte amino acid metabolism. Neurochem. Int. 36: 329-339.

Zahiri HS, Yoon SH, Keasling JD, Lee SH, Won Kim S, Yoon SC, Shin YC 2006 Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. Metab. Eng. 8: 406-416.

Zeng AP, Modak J, Deckwer WD 2002 Nonlinear dynamics of eucaryotic pyruvate dehydrogenase multienzyme complex: decarboxylation rate, oscillations, and multiplicity. Biotechnol. Prog. 18: 1265-1276.

Zeng RJ, Van Loosdrecht MC, Yuan Z, Keller J 2003 Metabolic model for glycogen-accumulating organisms in anaerobic/aerobic activated sludge systems. Biotechnol. Bioeng. 81: 92-105.

Zhang XQ, Powles SB 2006 The molecular bases for resistance to acetyl co-enzyme A carboxylase (ACCase) inhibiting herbicides in two target-based resistant biotypes of annual ryegrass (Lolium rigidum). Planta 223: 550-557.

Zhang Y, Li Y, Du C, Liu M, Cao Z 2006 Inactivation of aldehyde dehydrogenase: a key factor for engineering 1,3-propanediol production by Klebsiella pneumoniae. Metab. Eng. 8: 578-586.

Zhang YM, Rock CO, Jackowski S 2005 Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters. J. Biol. Chem. 280: 32594-32601.

Zhou D, White RH 1991 Early steps of isoprenoid biosynthesis in Escherichia coli. Biochem. J. 273: 627-634.

Ziegler A, Zaugg CE, Buser PT, Seelig J, Kunnecke B 2002 Non-invasive measurements of myocardial carbon metabolism using in vivo C-13 NMR spectroscopy. NMR Biomed. 15: 222-234.

Number of references = 182