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N Use By Plants
Nitrate Assimilation
Ammonia Assimilation
Glu, Gln, Asn, Gly, Ser
Aminotransferases
Asp, Ala, GABA
Val, Leu, Ileu, Thr, Lys
Pro, Arg, Orn
Polyamines
Non-protein AAs
Alkaloids
Sulfate Assimilation
Cys, Met, AdoMet, ACC
His, Phe, Tyr, Tryp
Secondary Products
Onium Compounds
Enzymes
Methods
Simulation
References
HORT640 - Metabolic Plant Physiology

References, APS kinase

Borges-Walmsley MI, Turner G, Bailey AM, Brown J, Lehmbeck J, Clausen IG. Isolation and characterisation of genes for sulphate activation and reduction in Aspergillus nidulans: implications for evolution of an allosteric control region by gene duplication. Mol. Gen. Genet. 247: 423-429 (1995).

Clarke DL, Newbert RW, Turner G. Cloning and characterisation of the adenosyl phosphosulphate kinase gene from Aspergillus nidulans. Curr. Genet. 32: 408-412 (1997).

Deyrup AT, Krishnan S, Cockburn BN, Schwartz NB. Deletion and site-directed mutagenesis of the ATP-binding motif (P-loop) in the bifunctional murine ATP-sulfurylase/adenosine 5'-phosphosulfate kinase enzyme. J. Biol. Chem. 273: 9450-9456 (1998).

Deyrup AT, Krishnan S, Singh B, Schwartz NB. Activity and stability of recombinant bifunctional rearranged and monofunctional domains of ATP-sulfurylase and adenosine 5'-phosphosulfate kinase. J. Biol. Chem. 274: 10751-10757 (1999).

Harada E, Kusano T, Sano H. Differential expression of genes encoding enzymes involved in sulfur assimilation pathways in response to wounding and jasmonate in Arabidopsis thaliana. J. Plant Physiol. 156: 272-276 (2000).

Lee S, Leustek T. APS kinase from Arabidopsis thaliana: genomic organization, expression, and kinetic analysis of the recombinant enzyme. Biochem. Biophys. Res. Commun. 247: 171-175 (1998).

Li H, Deyrup A, Mensch JR Jr, Domowicz M, Konstantinidis AK, Schwartz NB. The isolation and characterization of cDNA encoding the mouse bifunctional ATP sulfurylase-adenosine 5'-phosphosulfate kinase. J. Biol. Chem. 270: 29453-29459 (1995).

MacRae I, Segel IH. ATP sulfurylase from filamentous fungi: which sulfonucleotide is the true allosteric effector? Arch. Biochem. Biophys. 337: 17-26 (1997).

MacRae IJ, Rose AB, Segel IH. Adenosine 5'-phosphosulfate kinase from Penicillium chrysogenum. site-directed mutagenesis at putative phosphoryl-accepting and ATP P-loop residues. J. Biol. Chem. 273: 28583-28589 (1998).

MacRae IJ, Segel IH. Adenosine 5'-phosphosulfate (APS) kinase: diagnosing the mechanism of substrate inhibition. Arch. Biochem. Biophys. 361: 277-282 (1999).

Marzluf GA. Molecular genetics of sulfur assimilation in filamentous fungi and yeast. Annu. Rev. Microbiol. 51: 73-96 (1997).

Mugford SG, Yoshimoto N, Reichelt M, Wirtz M, Hill L, Mugford ST, Nakazato Y, Noji M, Takahashi H, Kramell R, Gigolashvili T, Flugge UI, Wasternack C, Gershenzon J, Hell R, Saito K, Kopriva S. Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites. Plant Cell 21: 910-927 (2009).

Ozeran JD, Westley J, Schwartz NB. Identification and partial purification of PAPS translocase. Biochemistry 35: 3695-3703 (1996).

Rosenthal E, Leustek T. A multifunctional Urechis caupo protein, PAPS synthetase, has both ATP sulfurylase and APS kinase activities. Gene 165: 243-248 (1995).

Schwartz NB, Lyle S, Ozeran JD, Li H, Deyrup A, Ng K, Westley J. Sulfate activation and transport in mammals: system components and mechanisms. Chem. Biol. Interact. 109: 143-151 (1998).

Setya A, Murillo M, Leustek T. Sulfate reduction in higher plants: molecular evidence for a novel 5'-adenylylsulfate reductase. Proc. Natl. Acad. Sci. U.S.A. 93: 13383-13388 (1996).

Shailubhai K, Singh RK, Schmuke JJ, Jacob GS. An enzymatic procedure for the preparation and purification of 3'-phosphoadenosine 5'-phospho-[35S]sulfate ([35S]PAPS): applications in syntheses of 8-azido and 8-bromo derivatives of [35S]PAPS. Anal. Biochem. 243: 165-170 (1996).

Uria-Nickelsen MR, Leadbetter ER, Godchaux W 3d. Sulfonate-sulfur assimilation by yeasts resembles that of bacteria. FEMS Microbiol. Lett. 114: 73-77 (1993).

Venkatachalam KV, Akita H, Strott CA. Molecular cloning, expression, and characterization of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase and its functional domains. J. Biol. Chem. 273: 19311-19320 (1998).

Venkatachalam KV, Fuda H, Koonin EV, Strott CA. Site-selected mutagenesis of a conserved nucleotide binding HXGH motif located in the ATP sulfurylase domain of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase. J. Biol. Chem. 274: 2601-2604 (1999).

Wray JL, Campbell EI, Roberts MA, Gutierrez-Marcos JF. Redefining reductive sulfate assimilation in higher plants: a role for APS reductase, a new member of the thioredoxin superfamily? Chem. Biol. Interact. 109: 153-167 (1998).

Yanagisawa K, Sakakibara Y, Suiko M, Takami Y, Nakayama T, Nakajima H, Takayanagi K, Natori Y, Liu MC. cDNA cloning, expression, and characterization of the human bifunctional ATP sulfurylase/adenosine 5'-phosphosulfate kinase enzyme. Biosci. Biotechnol. Biochem. 62: 1037-1040 (1998).

Number of references = 22

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