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HORT640 - Metabolic Plant Physiology
References, one and carbon
Angelaccio S, Chiaraluce R, Consalvi V, Buchenau B, Giangiacomo L, Bossa F, Contestabile R. Catalytic and thermodynamic properties of tetrahydromethanopterin-dependent serine hydroxymethyltransferase from Methanococcus jannaschii. J. Biol. Chem. 278: 41789-41797 (2003).
Appling DR. Compartmentation of folate-mediated one-carbon metabolism in eukaryotes. FASEB J. 5: 2645-2651 (1991).
Appling DR, Rabinowitz JC. Regulation of expression of the ADE3 gene for yeast C1-tetrahydrofolate synthase, a trifunctional enzyme involved in one-carbon metabolism. J. Biol. Chem. 260: 1248-1256 (1985).
Bagley PJ, Selhub J. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc. Natl. Acad. Sci. U.S.A. 95: 13217-13220 (1998).
Bago B, Pfeffer PE, Douds Jr DD, Brouillette J, Becard G, Shachar-Hill Y. Carbon metabolism in spores of the arbuscular mycorrhizal fungus Glomus intraradices as revealed by nuclear magnetic resonance spectroscopy. Plant Physiol. 121: 263-272 (1999).
Bailey LB, Gregory JF 3rd. Folate metabolism and requirements. J. Nutr. 129: 779-782 (1999).
Bailey LB, Gregory JF 3rd. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J. Nutr. 129: 919-922 (1999).
Barber RD, Donohue TJ. Function of a glutathione-dependent formaldehyde dehydrogenase in Rhodobacter sphaeroides formaldehyde oxidation and assimilation. Biochemistry 37: 530-537 (1998).
Barlowe CK, Appling DR. Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme. Mol. Cell Biol. 10: 5679-5687 (1990).
Barlowe CK, Appling DR. In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units. Biofactors 1: 171-176 (1988).
Bauwe H, Kolukisaoglu U. Genetic manipulation of glycine decarboxylation. J. Exp. Bot. 54: 1523-1535 (2003).
Bidulescu A, Chambless LE, Siega-Riz AM, Zeisel SH, Heiss G. Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutr. J. 8: 14 (2009).
Bottiglieri T, Hyland K, Reynolds EH. The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders. Drugs 48: 137-152 (1994).
Bright SW, Lea PJ, Miflin BJ. The regulation of methionine biosynthesis and metabolism in plants and bacteria. Ciba Found. Symp. 72: 101-117 (1979).
Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim. Pol. 51: 405-413 (2004).
Carl GF, Hudson FZ, McGuire BS Jr. Formyltetrahydrofolates associated with mitochondria have longer polyglutamate chains than the methyltetrahydrofolates associated with cytoplasm in rat brain. J. Nutr. 126: 3077-3082 (1996).
Celtikci B, Leclerc D, Lawrance AK, Deng L, Friedman HC, Krupenko NI, Krupenko SA, Melnyk S, James SJ, Peterson AC, Rozen R. Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice. Pharmacogenet. Genomics 18: 577-589 (2008).
Chen J, Kyte C, Valcin M, Chan W, Wetmur JG, Selhub J, Hunter DJ, Ma J. Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. Int. J. Cancer 110: 617-620 (2004).
Cherest H, Thomas D, Surdin-Kerjan Y. Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance of intact mitochondrial genome in Saccharomyces cerevisiae. J. Biol. Chem. 275: 14056-14063 (2000).
Chlumsky LJ, Zhang L, Jorns MS. Sequence analysis of sarcosine oxidase and nearby genes reveals homologies with key enzymes of folate one-carbon metabolism. J. Biol. Chem. 270: 18252-18259 (1995).
Choumenkovitch SF, Selhub J, Bagley PJ, Maeda N, Nadeau MR, Smith DE, Choi SW. In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific. J. Nutr. 132: 2157-2160 (2002).
Christensen B. Folate deficiency, cancer and congenital abnormalities. Is there a connection? Tidsskr Nor Laegeforen 116: 250-254 (1996).
Christensen KE, MacKenzie RE. Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals. Bioessays 28: 595-605 (2006).
Cook JD, Cichowicz DJ, George S, Lawler A, Shane B. Mammalian folylpoly-gamma-glutamate synthetase. 4. In vitro and in vivo metabolism of folates and analogues and regulation of folate homeostasis. Biochemistry 26: 530-539 (1987).
Cook RJ. Defining the steps of the folate one-carbon shuffle and homocysteine metabolism. Am. J. Clin. Nutr. 72: 1419-1420 (2000).
Cooke JEK, Brown KA, Wu R, Davis JM. Gene expression associated with N-induced shifts in resource allocation in poplar. Plant Cell Environ. 26: 757-770 (2003).
Cossins EA. One-carbon metabolism. The Biochemistry of Plants 2: 365-418 (1980).
Cossins EA. Folate biochemistry and the metabolism of one-carbon units. In "The Biochemistry of Plants" Volume 11, Academic Press, New York, pp. 317-353 (1987).
Cossins EA, Chan PY, Combepine G. One-carbon metabolism in Neurospora crassa wild-type and in mutants partially deficient in serine hydroxymethyltransferase. Biochem. J. 160: 305-314 (1976).
Cossins EA, Chen L. Folates and one-carbon metabolism in plants and fungi. Phytochemistry 45: 437-452 (1997).
Crowther GJ, Kosaly G, Lidstrom ME. Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1. J. Bacteriol. 190: 5057-5062 (2008).
Cybulski RL, Fisher RR. Intramitochondrial localization and proposed metabolic significance of serine transhydroxymethylase. Biochemistry 15: 3183-3187 (1976).
Dartois V, Liu J, Hoch JA. Alterations in the flow of one-carbon units affect KinB-dependent sporulation in Bacillus subtilis. Mol. Microbiol. 25: 39-51 (1997).
Delle Fratte S, White RH, Maras B, Bossa F, Schirch V. Purification and properties of serine hydroxymethyltransferase from Sulfolobus solfataricus. J. Bacteriol. 179: 7456-7461 (1997).
Depeint F, Bruce WR, Shangari N, Mehta R, O'brien PJ. Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways. Chem. Biol. Interact. 163: 113-132 (2006).
DeSouza L, Shen Y, Bognar AL. Disruption of cytoplasmic and mitochondrial folylpolyglutamate synthetase activity in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 376: 299-312 (2000).
Diaz de la Garza RI, Gregory JF 3rd, Hanson AD. Folate biofortification of tomato fruit. Proc. Natl. Acad. Sci. U.S.A. 104: 4218-4222 (2007).
Engel N, van den Daele K, Kolukisaoglu U, Morgenthal K, Weckwerth W, Parnik T, Keerberg O, Bauwe H. Deletion of glycine decarboxylase in Arabidopsis is lethal under nonphotorespiratory conditions. Plant Physiol. 144: 1328-1335 (2007).
Ferry JG. Enzymology of one-carbon metabolism in methanogenic pathways. FEMS Microbiol. Rev. 23: 13-38 (1999).
Fowler B. The folate cycle and disease in humans. Kidney Int. 59 (Suppl. 78): 221-229 (2001).
Fu TF, Rife JP, Schirch V. The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in mcf-7 cells as determined by 13C NMR. Arch. Biochem. Biophys. 393: 42-50 (2001).
Gaughan DJ, Barbaux S, Kluijtmans LA, Whitehead AS. The human and mouse methylenetetrahydrofolate reductase (MTHFR) genes: genomic organization, mRNA structure and linkage to the CLCN6 gene. Gene 257: 279-289 (2000).
Gelling CL, Piper MD, Hong SP, Kornfeld GD, Dawes IW. Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J. Biol. Chem. 279: 7072-7081 (2004).
Goyer A, Johnson TL, Olsen LJ, Collakova E, Shachar-Hill Y, Rhodes D, Hanson AD. Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis. J. Biol. Chem. 279: 16947-16953 (2004).
Green JM, MacKenzie RE, Matthews RG. Substrate flux through methylenetetrahydrofolate dehydrogenase: predicted effects of the concentration of methylenetetrahydrofolate on its partitioning into pathways leading to nucleotide biosynthesis or methionine regeneration. Biochemistry 27: 8014-8022 (1988).
Hagishita T, Yoshida T, Izumi Y, Mitsunaga T. Cloning and expression of the gene for serine-glyoxylate aminotransferase from an obligate methylotroph Hyphomicrobium methylovorum GM2. Eur. J. Biochem. 241: 1-5 (1996).
Hanson AD, Gage DA, Shachar-Hill Y. Plant one-carbon metabolism and its engineering. Trends Plant Sci. 5: 206-213 (2000).
Hanson AD, Gregory JF 3rd. Synthesis and turnover of folates in plants. Curr. Opin. Plant Biol. 5: 244-249 (2002).
Hanson AD, Roje S. One-carbon metabolism in higher plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 52: 119-137 (2001).
Hong SP, Piper MD, Sinclair DA, Dawes IW. Control of expression of one-carbon metabolism genes of Saccharomyces cerevisiae is mediated by a tetrahydrofolate-responsive protein binding to a glycine regulatory region including a core 5'-CTTCTT-3' motif. J. Biol. Chem. 274: 10523-10532 (1999).
Hopkins S, Schirch V. 5,10-Methenyltetrahydrofolate synthetase. Purification and properties of the enzyme from rabbit liver. J. Biol. Chem. 259: 5618-5622 (1984).
Igamberdiev AU, Bykova NV, Kleczkowski LA. Origins and metabolism of formate in higher plants. Plant Physiol. Biochem. 37: 503-513 (1999).
Jabrin S, Ravanel S, Gambonnet B, Douce R, Rebeille F. One-carbon metabolism in plants. Regulation of tetrahydrofolate synthesis during germination and seedling development. Plant Physiol. 131: 1431-1439 (2003).
James SJ, Melnyk S, Pogribna M, Pogribny IP, Caudill MA. Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology. J. Nutr. 132: 2361S-2366S (2002).
James TY, Boulianne RP, Bottoli APF, Granado JD, Aebi M, Kues U. The pab1 gene of Coprinus cinereus encodes a bifunctional protein for para-aminobenzoic acid (PABA) synthesis: implications for the evolution of fused PABA synthases. J. Basic Microbiol. 42: 91-103 (2002).
Jeong SS, Schirch V. Role of cytosolic serine hydroxymethyltransferase in one-carbon metabolism in Neurospora crassa. Arch. Biochem. Biophys. 335: 333-341 (1996).
Kastanos EK, Woldman YY, Appling DR. Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae. Biochemistry 36: 14956-14964 (1997).
Kim DW, Delle Fratte S, Jeong SS, Schirch V. Determination of serine hydroxymethyltransferase and reduced folate pools in tissue extracts. Anal. Biochem. 253: 201-209 (1997).
Kim JS, Lowe KE, Shane B. Regulation of folate and one-carbon metabolism in mammalian cells. IV. Role of folylpoly-gamma-glutamate synthetase in methotrexate metabolism and cytotoxicity. J. Biol. Chem. 268: 21680-21685 (1993).
Kim YI. Folate and DNA methylation: a mechanistic link between folate deficiency and colorectal cancer? Cancer Epidemiol. Biomarkers Prev. 13: 511-519 (2004).
Kruschwitz HL, McDonald D, Cossins EA, Schirch V. 5-Formyltetrahydropteroylpolyglutamates are the major folate derivatives in Neurospora crassa conidiospores. J. Biol. Chem. 269: 28757-28763 (1994).
Lee CP, Eubel H, O'Toole N, Millar AH. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Mol. Cell. Proteomics 7: 1297-1316 (2008).
Li R, Moore M, King J. Investigating the regulation of one-carbon metabolism in Arabidopsis thaliana. Plant Cell Physiol. 44: 233-241 (2003).
Liao YJ, Liu SP, Lee CM, Yen CH, Chuang PC, Chen CY, Tsai TF, Huang SF, Lee YH, Chen YM. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: implications of the gender disparity in liver cancer susceptibility. Int. J. Cancer 124: 816-826 (2009).
Lin BF, Huang RF, Shane B. Regulation of folate and one-carbon metabolism in mammalian cells. III. Role of mitochondrial folylpoly-gamma-glutamate synthetase. J. Biol. Chem. 268: 21674-21679 (1993).
Liu X, Szebenyi DM, Anguera MC, Thiel DJ, Stover PJ. Lack of catalytic activity of a murine mRNA cytoplasmic serine hydroxymethyltransferase splice variant: evidence against alternative splicing as a regulatory mechanism. Biochemistry 40: 4932-4939 (2001).
Loizeau K, De Brouwer V, Gambonnet B, Yu A, Renou JP, Van Der Straeten D, Lambert WE, Rebeille F, Ravanel S. A genome-wide and metabolic analysis determined the adaptive response of Arabidopsis cells to folate depletion induced by methotrexate. Plant Physiol. 148: 2083-2095 (2008).
Loizeau K, Gambonnet B, Zhang GF, Curien G, Jabrin S, Van Der Straeten D, Lambert WE, Rebeille F, Ravanel S. Regulation of one-carbon metabolism in Arabidopsis: the N-terminal regulatory domain of cystathionine gamma-synthase is cleaved in response to folate starvation. Plant Physiol. 145: 491-503 (2007).
Lowe KE, Osborne CB, Lin BF, Kim JS, Hsu JC, Shane B. Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of f-g-g synthetase substrate specificity and level on folate metabolism and f-g-gl specificity of metabolic cycles of one-carbon metabolism. J. Biol. Chem. 268: 21665-21673 (1993).
Macfarlane AJ, Liu X, Perry CA, Flodby P, Allen RH, Stabler SP, Stover PJ. Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J. Biol. Chem. 283: 25846-25853 (2008).
Macfarlane AJ, Perry CA, Girnary HH, Gao D, Allen RH, Stabler SP, Shane B, Stover PJ. Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J. Biol. Chem. 284: 1533-1539 (2009).
Martinez M, Cuskelly GJ, Williamson J, Toth JP, Gregory JF. Vitamin B-6 deficiency in rats reduces hepatic serine hydroxymethyltransferase and cystathionine beta-synthase activities and rates of in vivo protein turnover, homocysteine remethylation and transsulfuration. J. Nutr. 130: 1115-1123 (2000).
McClung CR, Davis CR, Page KM, Denome SA. Characterization of the formate (for) locus, which encodes the cytosolic serine hydroxymethyltransferase of Neurospora crassa. Mol. Cell Biol. 12: 1412-1421 (1992).
McNeil JB, Bognar AL, Pearlman RE. In vivo analysis of folate coenzymes and their compartmentation in Saccharomyces cerevisiae. Genetics 142: 371-381 (1996).
Melnyk S, Pogribna M, Pogribny IP, Yi P, James SJ. Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations. Clin. Chem. 46: 265-272 (2000).
Mesnard F, Roscher A, Garlick AP, Girard S, Baguet E, Arroo RR, Lebreton J, Robins RJ, Ratcliffe G. Evidence for the involvement of tetrahydrofolate in the demethylation of nicotine by Nicotiana plumbaginifolia cell-suspension cultures. Planta 214: 911-919 (2002).
Miyata A, Yoshida T, Yamaguchi K, Yokoyama C, Tanabe T, Toh H, Mitsunaga T, Izumi Y. Molecular cloning and expression of the gene for serine hydroxymethyltransferase from an obligate methylotroph Hyphomicrobium methylovorum GM2. Eur. J. Biochem. 212: 745-750 (1993).
Muskiet FA. The importance of (early) folate status to primary and secondary coronary artery disease prevention. Reprod. Toxicol. 20: 403-410 (2005).
Niculescu MD, Zeisel SH. Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. J. Nutr. 132: 2333S-2335S (2002).
Nieman KM, Hartz CS, Szegedi SS, Garrow TA, Sparks JD, Schalinske KL. Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats. Am. J. Physiol. Endocrinol. Metab. 291: E1235-E1242 (2006).
Nijhout HF, Reed MC, Anderson DF, Mattingly JC, James SJ, Ulrich CM. Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 1: 81-87 (2006).
Nijhout HF, Reed MC, Lam SL, Shane B, Gregory JF 3rd, Ulrich CM. In silico experimentation with a model of hepatic mitochondrial folate metabolism. Theor. Biol. Med. Model. 3: 40 (2006).
Nour JM, Rabinowitz JC. Isolation, characterization, and structural organization of 10-formyltetrahydrofolate synthetase from spinach leaves. J. Biol. Chem. 266: 18363-18369 (1991).
Ogawa H, Gomi T, Fujioka M. Serine hydroxymethyltransferase and threonine aldolase: are they identical? Int. J. Biochem. Cell Biol. 32: 289-301 (2000).
Ogur M, Liu TN, Cheung I, Paulavicius I, Wales W, Mehnert D, Blaise D. "Active" one-carbon generation in Saccharomyces cerevisiae. J. Bacteriol. 129: 926-933 (1977).
Oppenheim EW, Adelman C, Liu X, Stover PJ. Heavy chain ferritin enhances serine hydroxymethyltransferase expression and de novo thymidine biosynthesis. J. Biol. Chem. 276: 19855-19861 (2001).
Osborne CB, Lowe KE, Shane B. Regulation of folate and one-carbon metabolism in mammalian cells. I. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-gamma-glutamate synthetase activity. J. Biol. Chem. 268: 21657-21664 (1993).
Pasternack LB, Laude DA Jr, Appling DR. 13C NMR detection of folate-mediated serine and glycine synthesis in vivo in Saccharomyces cerevisiae. Biochemistry 31: 8713-8719 (1992).
Pasternack LB, Laude DA Jr, Appling DR. 13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae. Biochemistry 33: 74-82 (1994).
Pasternack LB, Laude DA Jr, Appling DR. Whole-cell detection by 13C NMR of metabolic flux through the C1-tetrahydrofolate synthase/serine hydroxymethyltransferase enzyme system and effect of antifolate exposure in Saccharomyces cerevisiae. Biochemistry 33: 7166-7173 (1994).
Pasternack LB, Littlepage LE, Laude DA Jr, Appling DR. 13C NMR analysis of the use of alternative donors to the tetrahydrofolate-dependent one-carbon pools in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 326: 158-165 (1996).
Perry C, Sastry R, Nasrallah IM, Stover PJ. Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication. J. Biol. Chem. 280: 396-400 (2005).
Piper MD, Hong SP, Ball GE, Dawes IW. Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J. Biol. Chem. 275: 30987-30995 (2000).
Plamann MD, Rapp WD, Stauffer GV. Escherichia coli K12 mutants defective in the glycine cleavage enzyme system. Mol. Gen. Genet. 192: 15-20 (1983).
Rajinikanth M, Harding SA, Tsai CJ. The glycine decarboxylase complex multienzyme family in Populus. J. Exp. Bot. 58: 1761-1770 (2007).
Ravanel S, Block MA, Rippert P, Jabrin S, Curien G, Rebeille F, Douce R. Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol. J. Biol. Chem. 279: 22548-22557 (2004).
Ravanel S, Cherest H, Jabrin S, Grunwald D, Surdin-Kerjan Y, Douce R, Rebeille F. Tetrahydrofolate biosynthesis in plants: molecular and functional characterization of dihydrofolate synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A. 98: 15360-15365 (2001).
Reed MC, Nijhout HF, Neuhouser ML, Gregory JF 3rd, Shane B, James SJ, Boynton A, Ulrich CM. A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J. Nutr. 136: 2653-2661 (2006).
Renwick SB, Snell K, Baumann U. The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy. Structure 6: 1105-1116 (1998).
Roje S, Chan SY, Kaplan F, Raymond RK, Horne DW, Appling DR, Hanson AD. Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo. J. Biol. Chem. 277: 4056-4061 (2002).
Roje S, Wang H, McNeil SD, Raymond RK, Appling DR, Shachar-Hill Y, Bohnert HJ, Hanson AD. Isolation, characterization, and functional expression of cDNAs encoding NADH-dependent methylenetetrahydrofolate reductase from higher plants. J. Biol. Chem. 274: 36089-36096 (1999).
Rosowsky A, Forsch RA, Null A, Moran RG. 5-Deazafolate analogues with a rotationally restricted glutamate or ornithine side chain: synthesis and binding interaction with folylpolyglutamate synthetase. J. Med. Chem. 42: 3510-3519 (1999).
Rossbach S, Hennecke H. Identification of glyA as a symbiotically essential gene in Bradyrhizobium japonicum. Mol. Microbiol. 5: 39-47 (1991).
Schalinske KL, Steele RD. Quantification of the carbon flow through the folate-dependent one-carbon pool using radiolabeled histidine: effect of altered thyroid and folate status. Arch. Biochem. Biophys. 328: 93-100 (1996).
Scheer JB, Mackey AD, Gregory JF 3rd. Activities of hepatic cytosolic and mitochondrial forms of serine hydroxymethyltransferase and hepatic glycine concentration are affected by vitamin B-6 intake in rats. J. Nutr. 135: 233-238 (2005).
Schirch LV, Tatum CM Jr, Benkovic SJ. Serine transhydroxymethylase: evidence for a sequential random mechanism. Biochemistry 16: 410-419 (1977).
Schirch V, Strong WB. Interaction of folylpolyglutamates with enzymes in one-carbon metabolism. Arch. Biochem. Biophys. 269: 371-380 (1989).
Schlawicke Engstrom K, Nermell B, Concha G, Stromberg U, Vahter M, Broberg K. Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions. Mutat. Res. 667: 4-14 (2009).
Scott J, Rebeille F, Fletcher J. Folic acid and folates: the feasibility for nutritional enhancement in plant foods. J. Sci. Food Agric. 80: 795-824 (2000).
Scott JM, Weir DG. Folic acid, homocysteine and one-carbon metabolism: a review of the essential biochemistry. J. Cardiovasc. Risk 5: 223-227 (1998).
Sekowska A, Danchin A. Identification of yrrU as the methylthioadenosine nucleosidase gene in Bacillus subtilis. DNA Res. 6: 255-264 (1999).
Shane B. Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism. Vitam. Horm. 45: 263-335 (1989).
Shaw GM, Carmichael SL, Yang W, Selvin S, Schaffer DM. Periconceptional dietary intake of choline and betaine and neural tube defects in offspring. Am. J. Epidemiol. 160: 102-109 (2004).
Sinclair DA, Dawes IW. Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae. Genetics 140: 1213-1222 (1995).
Sirotnak FM, Tolner B. Carrier-mediated membrane transport of folates in mammalian cells. Annu. Rev. Nutr. 19: 91-122 (1999).
Skogman GS, Sjostrom JE. Factors affecting the biosynthesis of L-tryptophan by genetically modified strains of Escherichia coli. J. Gen. Microbiol. 130: 3091-3100 (1984).
Slocombe SP, Schauvinhold I, McQuinn RP, Besser K, Welsby NA, Harper A, Aziz N, Li Y, Larson TR, Giovannoni J, Dixon RA, Broun P. Transcriptomic and reverse genetic analyses of branched chain fatty acid and acyl sugar production in Solanum pennellii and Nicotiana benthamiana. Plant Physiol. 148: 1830-1846 (2008).
Song JM, Rabinowitz JC. Function of yeast cytoplasmic C1-tetrahydrofolate synthase. Proc. Natl. Acad. Sci. U.S.A. 90: 2636-2640 (1993).
Stam F, Smulders YM, van Guldener C, Jakobs C, Stehouwer CD, de Meer K. Folic acid treatment increases homocysteine remethylation and methionine transmethylation in healthy subjects. Clin. Sci. (Lond.) 108: 449-456 (2005).
Stam F, van Guldener C, ter Wee PM, Kulik W, Smith DE, Jakobs C, Stehouwer CD, de Meer K. Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine. Am. J. Physiol. Renal Physiol. 287: F215-F223 (2004).
Starkenburg SR, Larimer FW, Stein LY, Klotz MG, Chain PS, Sayavedra-Soto LA, Poret-Peterson AT, Gentry ME, Arp DJ, Ward B, Bottomley PJ. Complete genome sequence of Nitrobacter hamburgensis X14 and comparative genomic analysis of species within the genus Nitrobacter. Appl. Environ. Microbiol. 74: 2852-2863 (2008).
Steegers-Theunissen RP. Folate metabolism and neural tube defects: a review. Eur. J. Obstet. Gynecol .Reprod. Biol. 61: 39-48 (1995).
Stover P, Schirch V. 5-Formyltetrahydrofolate polyglutamates are slow tight binding inhibitors of serine hydroxymethyltransferase. J. Biol. Chem. 266: 1543-1550 (1991).
Stover P, Schirch V. Serine hydroxymethyltransferase catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 5-formyltetrahydrofolate. J. Biol. Chem. 265: 14227-14233 (1990).
Strong WB, Schirch V. In vitro conversion of formate to serine: effect of tetrahydropteroylpolyglutamates and serine hydroxymethyltransferase on the rate of 10-formyltetrahydrofolate synthetase. Biochemistry 28: 9430-9439 (1989).
Sun X, Cross JA, Bognar AL, Baker EN, Smith CA. Folate-binding triggers the activation of folylpolyglutamate synthetase. J. Mol. Biol. 310: 1067-1078 (2001).
Suzuki T, Matsuo K, Hirose K, Hiraki A, Kawase T, Watanabe M, Yamashita T, Iwata H, Tajima K. One-carbon metabolism-related gene polymorphisms and risk of breast cancer. Carcinogenesis 29: 356-362 (2008).
Szebenyi DM, Musayev FN, di Salvo ML, Safo MK, Schirch V. Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism. Biochemistry 43: 6865-6876 (2004).
Tanaka T, Scheet P, Giusti B, Bandinelli S, Piras MG, Usala G, Lai S, Mulas A, Corsi AM, Vestrini A, Sofi F, Gori AM, Abbate R, Guralnik J, Singleton A, Abecasis GR, Schlessinger D, Uda M, Ferrucci L. Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. Am. J. Hum Genet. 84: 477-482 (2009).
Tang C, Zhang Z, Xu B, Li M, Liu J, Cui J. Two newly synthesized 5-methyltetrahydrofolate-like compounds inhibit methionine synthase activity accompanied by cell cycle arrest in G1/S phase and apoptosis in vitro. Anticancer Drugs 19: 697-704 (2008).
Tanghe KA, Garrow TA, Schalinske KL. Triiodothyronine treatment attenuates the induction of hepatic glycine N-methyltransferase by retinoic acid and elevates plasma homocysteine concentrations in rats. J. Nutr. 134: 2913-2918 (2004).
Thomas D, Becker A, Surdin-Kerjan Y. Reverse methionine biosynthesis from S-adenosylmethionine in eukaryotic cells. J. Biol. Chem. 275: 40718-40724 (2000).
Tisdale MJ. Methionine synthesis from 5'-methylthioadenosine by tumour cells. Biochem. Pharmacol. 32: 2915-2920 (1983).
Townsend JH, Davis SR, Mackey AD, Gregory JF. Folate deprivation reduces homocysteine remethylation in a human intestinal epithelial cell culture model: role of serine in one-carbon donation. Am. J. Physiol. Gastroint. Liver Physiol. 286: G588-G595 (2004).
Ueland PM, Holm PI, Hustad S. Betaine: a key modulator of one-carbon metabolism and homocysteine status. Clin. Chem. Lab. Med. 43: 1069-1075 (2005).
van der Hoeven RS, Steffens JC. Biosynthesis and elongation of short- and medium-chain-length fatty acids. Plant Physiol. 122: 275-282 (2000).
Wahls WP, Song JM, Smith GR. Single-stranded DNA binding activity of C1-tetrahydrofolate synthase enzymes. J. Biol. Chem. 268: 23792-23798 (1993).
West MG, Horne DW, Appling DR. Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae. Biochemistry 35: 3122-3132 (1996).
Wu K, Cossins EA, King J. Folate metabolism in Datura innoxia. In vivo and in vitro folylpolyglutamate synthesis in wild-type and methotrexate-resistant cells. Plant Physiol. 104: 373-380 (1994).
Young PG, Smith CA, Metcalf P, Baker EN. Structures of Mycobacterium tuberculosisfolylpolyglutamate synthase complexed with ADP and AMPPCP. Acta Crystallogr. D. Biol. Crystallogr. 64: 745-753 (2008).
Number of references = 140
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