Definitions

Definitions:

E1 = Specific activity of exogenously supplied precursor, E (nCi.nmol^-1)

E2 = Initial pool size of exogenously supplied precursor (nmol.gfw^-1)

TS = Total time of the simulation (min)

k = A variable that determines the rate of uptake of the exogenously supplied precursor, A5 = E2.k; as the pool of E2 declines, the rate of uptake of E2 declines proportionately

A1 = Initial specific activity of pool A (nCi.nmol^-1)

A2 = Initial pool size of pool A (nmol.gfw^-1)

A3 = Rate of synthesis of pool A (nmol.min^-1.gfw^-1)

A4 = Combined rate of utilization of pool A (nmol.min^-1.gfw^-1)

F1 = Specific activity of endogenous unlabeled precursor of pool A (nCi.nmol^-1)

B1 = Initial specific activity of pool B (nCi.nmol^-1)

B2 = Initial pool size of pool B (nmol.gfw^-1)

B3 = Rate of synthesis of pool B (nmol.min^-1.gfw^-1)

B4 = Combined rate of utilization of pool B (nmol.min^-1.gfw^-1)

C1 = Initial specific activity of pool C (nCi.nmol^-1)

C2 = Initial pool size of pool C (nmol.gfw^-1)

C3 = Rate of synthesis of pool C (nmol.min^-1.gfw^-1)

C4 = Combined rate of utilization of pool C (nmol.min^-1.gfw^-1)

D1 = Initial specific activity of pool D (nCi.nmol^-1)

D2 = Initial pool size of pool D (nmol.gfw^-1)

D3 = Rate of synthesis of pool D (nmol.min^-1.gfw^-1)

gfw = g fresh weight